Infectious Diseases News and Research

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NIH awards ADi Phase II SBIR grant to scan Plasmodium falciparum proteome for protective antigens

Antigen Discovery, Inc. today announced that it has received a Phase II Small Business Innovation and Research award from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health. The three-year award, totaling approximately $ 2.5 million, is a continuation of a Phase I SBIR grant to scan the Plasmodium falciparum proteome for protective antigens.

13 Aug 2012

New 3-D view of the body's response to infection

A new 3-D view of the body's response to infection - and the ability to identify proteins involved in the response - could point to novel biomarkers and therapeutic agents for infectious diseases.

13 Aug 2012

Insight into ubiquitin system

A faulty gene linked to a rare blood vessel disorder has led investigators to discover a mechanism involved in determining the fate of possibly thousands of proteins working inside cells.

13 Aug 2012

Breakthrough vaccine against deadly Nipah virus

A major breakthrough in the development of a highly effective vaccine against the deadly Nipah virus has been reported by a team of federal and university scientists. The results of their study, "A Hendra virus G glycoprotein subunit vaccine protects African green monkeys from Nipah virus challenge," will appear in Science Translational Medicine online.

10 Aug 2012

Accurate vaccination needed to protect children

This year the U.S. has seen the worst outbreak of whooping cough in more than 50 years. In fact, it has reached epidemic levels in many states and the Centers for Disease Control and Prevention said the numbers of cases reported is already twice as many as last year. With kids getting ready to head back-to-school, the numbers of children impacted or killed by this disease could continue to rise if children aren't accurately vaccinated.

10 Aug 2012

Hydrocephalus dictates age-related SAH outcomes

Age is only predictive of poor outcome after aneurysmal subarachnoid hemorrhage because of its association with hydrocephalus, say researchers.

10 Aug 2012

$Thoracolumbar vertebrae fracture may be ‘silent’$

Thoracolumbar vertebrae fracture may be ‘silent’

Imaging is essential to avoid missing fractures to the thoracolumbar vertebrae in patients who have sustained blunt injury, UK researchers say.

10 Aug 2012

Anemia prevention in pregnancy: an interview with Juan Pablo Peña-Rosas, WHO

Anaemia is a condition in which the number of red blood cells in the body is lower than normal or these have lower amounts of haemoglobin, a protein that is involved in the oxygen exchange of the body.

10 Aug 2012

Researchers urge shakeup to laparoscopic cholecystectomy timing

The tradition of delaying laparoscopic cholecystectomy after hospital admission for mild gallstone pancreatitis may be unnecessary, say the authors of a US study.

9 Aug 2012

University of Nevada researcher to optimize new rapid test for melioidosis

A new rapid test to diagnose melioidosis, a difficult infection to treat - and classified as a biothreat by the Centers for Disease Control and Prevention - is being optimized and tested by University of Nevada School of Medicine researcher David AuCoin.

9 Aug 2012

Study highlights uncertain value of tachypnea at triage

The usual method of assessing respiratory rate at triage in the emergency department is highly insensitive for the presence of tachypnea, say researchers.

8 Aug 2012

BioDiem granted European patent for antimicrobial drug

Australian vaccine development company BioDiem Ltd (ASX: BDM) announced today the successful granting of a key European patent for its synthetic antimicrobial compound BDM-I. BDM-I is a novel compound active against a range of pathogenic micro-organisms including bacteria, fungi and protozoa. The patent provides protection around BDM-I as a treatment for vulvovaginitis, a general term for inflammation of the vulva or vagina.

7 Aug 2012

Children with negative TB skin test at high risk for mortality

Children with clinical signs of tuberculosis but with a negative tuberculin skin test result should not have treatment delayed, suggest study findings showing that false-negatives are common and associated with high mortality.

7 Aug 2012

Creating new non-influenza vaccines: an interview with Julie Phillips, CEO of BioDiem

BioDiem recently signed a collaborative agreement with The Royal Melbourne Institute of Technology (RMIT) for the development of non-influenza vaccines using BioDiem’s proprietary live attenuated influenza virus (LAIV) technology.

7 Aug 2012

Applied BioCode receives U.S. patent for ‘Light Transmitted Assay Beads’

Applied BioCode, Inc. today announced that the United Stated Patent and Trademark Office has granted US Patent #8,232,092 "Light Transmitted Assay Beads," describing the method of decoding barcodes and analyzing bioassays using Barcoded Magnetic Beads (BMB) multiplex products.

7 Aug 2012

Advances in HIV/AIDS therapy and the International AIDS Conference: an interview with Professor Sharon Lewin

The anti-HIV drugs, also known as anti-retroviral therapy, came about in the mid ‘90’s. These involved using at least 3 different drugs together.

7 Aug 2012

Manning ICU with 24-hour specialist staff does not improve long-term survival

Having round-the-clock rather than on-demand presence of an intensivist does not increase intensive care unit patients’ long-term survival rates, report US researchers.

6 Aug 2012

Early CT ‘definitive’ for subarachnoid hemorrhage diagnosis

Cerebrospinal fluid analysis is only necessary for patients with thunderclap headache and a negative computed tomography scan if they undergo imaging more than 6 hours after headache onset, research suggests.

6 Aug 2012

Giving antibiotics just before cesarean section prevents infections

Giving antibiotics before cesarean section surgery rather than just after the newborn's umbilical cord is clamped cuts the infection rate at the surgical site in half, according to researchers at Washington University School of Medicine in St. Louis and Barnes-Jewish Hospital.

3 Aug 2012

Alcoholics are often going undiagnosed

Medical staff often do not spot alcohol problems in their patients unless they are already intoxicated, say UK researchers from the University of Leicester.

3 Aug 2012