Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

People with higher Leptin levels have significantly reduced incidence of AD and dementia

This week’s issue of the Journal of the American Medical Association (Dec 16) features a report on a long-term, prospective study of elderly, dementia-free individuals led by researchers from Boston University School of Medicine and the Framingham Heart Study focusing on the association between the protein hormone Leptin and the risk of developing Alzheimer’s disease (AD).

17 Dec 2009

People are more prone to Crohn's disease and ulcerative colitis, explains new research

New research by the University of Adelaide could help explain why some people are more prone to Crohn's disease, ulcerative colitis and other autoimmune diseases.

17 Dec 2009

Researchers discover new gene involved in lung cancer using DNA sequencing technology

Aided by next-generation DNA sequencing technology, an international team of researchers has gained insights into how more than 60 carcinogens associated with cigarette smoke bind to and chemically modify human DNA, ultimately leading to cancer-causing genetic mutations.

17 Dec 2009

ChromoCure's new Southeast Research Center to be based in Aventura, Florida

ChromoCure, Inc. announced today its new Southeast Research Center to be based in Aventura, Florida.

17 Dec 2009

BUSM Pulmonary Center awarded $1.4M grant to derive stem cells and lung progenitors from lung disease patients

Boston University School of Medicine's (BUSM) Pulmonary Center has received a two-year $1.4 million grant from the National Heart, Lung, and Blood Institute to derive stem cells and lung progenitors from patients with lung disease.

16 Dec 2009

ChemoCentryx commences enrollment in CCX354 Phase 2 clinical trial for RA

ChemoCentryx, Inc. today announced that it has begun enrolling patients in a Phase 2 clinical trial of CCX354, an orally-bioavailable, novel, small molecule drug designed to specifically target the CCR1 chemokine receptor for the treatment of rheumatoid arthritis (RA).

16 Dec 2009

EMD Serono, Brigham and Women's Hospital collaborate in MS research

EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, today announced a strategic collaboration with Brigham and Women's Hospital in Boston, to advance basic and clinical research in multiple sclerosis (MS), with the goal of generating new and innovative discoveries that advance treatment for people living with this condition. The multi-faceted agreement will run for up to 5 years, with the potential to renew the alliance thereafter. Both parties decided not to disclose financial details.

16 Dec 2009

DNA reveals earliest proven case of leprosy, Turin Shroud not from Jesus-era Jerusalem

The DNA of a 1st century shrouded man found in a tomb on the edge of the Old City of Jerusalem has revealed the earliest proven case of leprosy. Details of the research will be published December 16 in the PloS ONE Journal.

16 Dec 2009

Human Rhodesian sleeping sickness in Uganda points to infected livestock movements

The northwards spread of human Rhodesian sleeping sickness in Uganda is likely due to the movement of infected livestock, according to new findings from an interdisciplinary research group including members from the Centre for Infectious Diseases, University of Edinburgh; the Ministry of Health, Uganda; and the Universities of Oxford and Southampton.

16 Dec 2009

Chagas disease transmission in Peru linked to migration and urbanization patterns

New research shows how the migration and settlement patterns associated with the rapid urbanization of Peru may link to Chagas disease transmission. The

16 Dec 2009

Higher leptin levels associated with lower incidence of AD and dementia

Persons with higher levels of leptin, a protein hormone produced by fat cells and involved in the regulation of appetite, may have an associated reduced incidence of Alzheimer disease and dementia, according to a study in the December 16 issue of JAMA.

16 Dec 2009

UCLA researchers find link between brain cancer and fatty acid synthesis

Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according to a first-of-its-kind study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

16 Dec 2009

Results from five new studies on Genomic Health's Oncotype DX breast cancer test announced

Genomic Health, Inc. today announced results from five new studies on its Oncotype DX® breast cancer test, a multi-gene expression test that physicians currently use to predict the likelihood of chemotherapy benefit and recurrence risk for patients with early-stage breast cancer.

16 Dec 2009

Scientists identify protein switch that helps prevent liver cancer

A team of scientists from the UC San Diego School of Medicine and Osaka University in Japan have identified a protein switch that helps prevent liver damage, including inflammation, fibrosis and cancer. The findings suggest that a better understanding of how the protein, TAK1, works could lead to new insights into the development of liver disease and cancer.

15 Dec 2009

UT Southwestern Medical Center performs minimally invasive procedures for sinuses and chronic rhinosinusitis

Only about one in 2,000 people in the United States get a sinus tumor, but Johnnie Wilcox was one of the unfortunate few.

15 Dec 2009

Clarient and BioView team up to develop diagnostic tool for early detection of lung cancer

Clarient, Inc., a premier technology and services resource for pathologists, oncologists and the pharmaceutical industry, and BioView Ltd. (TASE: BIOV) today jointly announced that they will collaborate on studies to validate the clinical utility of a non-invasive test for the early detection of non-small cell lung cancer.

14 Dec 2009

ICON expands its European Central Laboratory in Dublin

ICON plc,a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries, today announced that it has expanded its European Central Laboratory, located in South County Business Park, Dublin.

14 Dec 2009

Researchers present new data for diagnosis and management of beast cancer

As therapies for breast cancer continue to emerge, the issues of how to best monitor success and gauge prognosis remain important questions.

14 Dec 2009

Additional therapy and screening may be needed for patients with mucinous breast cancer

In a large review of breast cancer patients with mucinous carcinoma, researchers at The University of Texas M. D. Anderson Cancer Center have identified an association between this rare type of breast cancer long-associated with a favorable prognosis and multiple tumors undetected by mammography or ultrasound.

14 Dec 2009

Texas researchers identify new detection method for circulating tumor cells

Circulating metastatic breast cancer cells can lose their epithelial receptors, a process that enables them to travel through the bloodstream undetected, according to research from The University of Texas M. D. Anderson Cancer Center.

14 Dec 2009

Pathology News and Research

Further Reading

People with higher Leptin levels have significantly reduced incidence of AD and dementia

People are more prone to Crohn's disease and ulcerative colitis, explains new research

Researchers discover new gene involved in lung cancer using DNA sequencing technology

ChromoCure's new Southeast Research Center to be based in Aventura, Florida

BUSM Pulmonary Center awarded $1.4M grant to derive stem cells and lung progenitors from lung disease patients

ChemoCentryx commences enrollment in CCX354 Phase 2 clinical trial for RA

EMD Serono, Brigham and Women's Hospital collaborate in MS research

DNA reveals earliest proven case of leprosy, Turin Shroud not from Jesus-era Jerusalem

Human Rhodesian sleeping sickness in Uganda points to infected livestock movements

Chagas disease transmission in Peru linked to migration and urbanization patterns

Higher leptin levels associated with lower incidence of AD and dementia

UCLA researchers find link between brain cancer and fatty acid synthesis

Results from five new studies on Genomic Health's Oncotype DX breast cancer test announced

Scientists identify protein switch that helps prevent liver cancer

UT Southwestern Medical Center performs minimally invasive procedures for sinuses and chronic rhinosinusitis

Clarient and BioView team up to develop diagnostic tool for early detection of lung cancer

ICON expands its European Central Laboratory in Dublin

Researchers present new data for diagnosis and management of beast cancer

Additional therapy and screening may be needed for patients with mucinous breast cancer

Texas researchers identify new detection method for circulating tumor cells

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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