Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Androgen receptor plays critical role in wound healing

A molecular receptor pivotal to the action of male hormones such as testosterone also plays a crucial role in the body's ability to heal, report scientists in the December issue of the Journal of Clinical Investigation.

5 Jan 2010

Study identifies novel factor that causes Alzheimer's disease

Inheritance of an extra copy of the gene- β -amyloid precursor protein, APP, in individuals with Down syndrome leads to the inevitable development of early onset Alzheimer's disease, known to be linked to the deposition of Amyloid β peptide or Aβ in the brain.

5 Jan 2010

Experimental lung cancer drug promising against brain cancer glioblastoma and prostate cancer

An experimental drug currently being tested against breast and lung cancer shows promise in fighting the brain cancer glioblastoma and prostate cancer, researchers at UT Southwestern Medical Center have found in two preclinical studies.

4 Jan 2010

Scientists identify genetic marker to diagnose DFTD

An international team of scientists led by a Cold Spring Harbor Laboratory (CSHL) investigator has discovered that the deadly facial tumors decimating Australia's Tasmanian devil population probably originated in Schwann cells, a type of tissue that cushions and protects nerve fibers.

4 Jan 2010

Presence of Streptococcus pneumoniae could predict risk of severe disease in H1N1 pandemic influenza

The presence of the Streptococcus pneumoniae in samples that can be easily obtained in clinics and emergency rooms may predict risk of severe disease in H1N1 pandemic influenza.

31 Dec 2009

Researchers study the effectiveness of colonoscopy in preventing colorectal cancer

The prevalence of left-sided advanced colorectal neoplasms was lower in participants in a community setting, but not right-sided advanced neoplams, who had received a colonoscopy in the preceding 10 years, according to a new study published online December 30 in the Journal of the National Cancer Institute.

31 Dec 2009

Researchers develop automated system to differentiate strains of influenza

Researchers from the Medical College of Wisconsin, the Children's Research Institute, and the Children's Hospital of Wisconsin have developed a rapid, automated system to differentiate strains of influenza.

30 Dec 2009

TRAP-1 may prevent cancer cell death, current research suggests

Current research suggests that TNF-receptor associated protein-1 (TRAP-1) may prevent cancer cell death. The related report by Leav et al, "Cytoprotective Mitochondrial Chaperone TRAP-1 as a Novel Molecular Target in Localized and Metastatic Prostate Cancer," appears in the January 2010 issue of the American Journal of Pathology.

30 Dec 2009

Small molecules reverse protein trafficking and mitochondrial dysfunction in Parkinson's disease models

Parkinson's disease is a neurodegenerative disorder characterized by tremors, muscle rigidity, and slowed movements. There is currently no cure for the disease, and current Parkinson's therapies only address disease symptoms, not the disease's cellular cause.

29 Dec 2009

Grant of $2 million awarded to understand PIGD in Parkinson's disease

The Michael J. Fox Foundation for Parkinson's Research has awarded a total of $2 million to five research teams carrying out clinical studies to refine understanding of postural instability and gait disturbances (PIGD) in Parkinson's disease, and help speed the development of urgently needed treatments.

29 Dec 2009

Sudden worldwide increase in antibiotic-resistant bacterium, a cause for concern

A sudden worldwide increase in an antibiotic-resistant bacterium is cause for concern, according to a review in f1000 Medicine Reports.

28 Dec 2009

Researchers at Stanford University School of Medicine identify a critical component, Jarid2

Like a child awaiting the arrival of Christmas, embryonic stem cells exist in a state of permanent anticipation. They must balance the ability to quickly become more specialized cell types with the cellular chaos that could occur should they act too early (stop shaking those presents, kids!).

28 Dec 2009

Potential new therapeutic option for prevention of PD-associated neuropathology

Scientists have identified a synergistic interaction that disrupts normal intracellular transport mechanisms and leads to the accumulation of neuron-damaging clumps of protein associated with Parkinson's disease (PD), a neurodegenerative disorder that is characterized by a specific loss of neurons in the midbrain and brainstem. The research, published by Cell Press in the December 24 issue of the journal Neuron, identifies a new potential therapeutic option for preventing PD-associated neuropathology.

24 Dec 2009

Scientists use DNA sequence to characterize genome rearrangement in breast cancer samples

The first detailed search of breast cancer genomes to uncover genomic rearrangements is published today. The team characterised the ways in which the human genome is broken and put back together in 24 cases of breast cancer.

23 Dec 2009

National MS Society calls for grant applications to examine the impact of CCSVI hypothesis

2009 saw exciting research progress, unprecedented opportunities on the horizon, and more scientists than ever working on resolving important questions. Despite the year's economic and financial challenges, the National Multiple Sclerosis Society continues to propel research forward to end MS. In 2009 the Society provided over $33.5 million to support 345 new and ongoing projects in its research portfolio, plus $1.5 million for Fast Forward, the Society's drug development subsidiary which continues to attract new funding streams.

23 Dec 2009

Nationwide Children's Hospital chosen as a BCR for TCGA

Nationwide Children's Hospital recently was awarded an initial $5.5 million contract from the National Cancer Institute (NCI) to serve as a Biospecimen Core Resource (BCR) for The Cancer Genome Atlas (TCGA), a program co-managed by the NCI and the National Human Genome Research Institute (NHGRI), both part of the National Institutes of Health (NIH).

23 Dec 2009

Brazilian researchers perform autopsy study to examine the causes H1N1 death

Brazilian researchers have performed the first-ever autopsy study to examine the precise causes of death in victims of the H1N1 swine flu.

23 Dec 2009

U.S. Congress approves $1.6 million for AdMeTech Foundation's research program

AdMeTech Foundation, a nonprofit organization, announced today that the U.S. Congress has approved $1.6 million for funding of its groundbreaking research program aimed at developing novel imaging technologies for early prostate cancer detection, which in turn is critical for saving lives and designing customized patient care, including the most effective and the least invasive approach.

23 Dec 2009

Prolonged exposure to higher levels of pollutants can lead to hospitalization for pneumonia

A McMaster University researcher has found the first evidence that prolonged exposure to higher levels of the pollutants found in car exhaust fumes and industrial air pollution can lead to hospitalization for pneumonia in adults aged 65 and older.

23 Dec 2009

New drug to stop cancer cells from growing and to stimulate immune system to destroy cancer cells found

A study conducted at Scott & White Healthcare in Temple, Texas, found that a new drug stopped the growth of breast tumors in mice. This drug is unique in that it works both by stopping the cancer cells from growing and metastasizing to other organs, and by stimulating the immune system to destroy breast cancer cells and keeps them from coming back.

23 Dec 2009

Pathology News and Research

Further Reading

Androgen receptor plays critical role in wound healing

Study identifies novel factor that causes Alzheimer's disease

Experimental lung cancer drug promising against brain cancer glioblastoma and prostate cancer

Scientists identify genetic marker to diagnose DFTD

Presence of Streptococcus pneumoniae could predict risk of severe disease in H1N1 pandemic influenza

Researchers study the effectiveness of colonoscopy in preventing colorectal cancer

Researchers develop automated system to differentiate strains of influenza

TRAP-1 may prevent cancer cell death, current research suggests

Small molecules reverse protein trafficking and mitochondrial dysfunction in Parkinson's disease models

Grant of $2 million awarded to understand PIGD in Parkinson's disease

Sudden worldwide increase in antibiotic-resistant bacterium, a cause for concern

Researchers at Stanford University School of Medicine identify a critical component, Jarid2

Potential new therapeutic option for prevention of PD-associated neuropathology

Scientists use DNA sequence to characterize genome rearrangement in breast cancer samples

National MS Society calls for grant applications to examine the impact of CCSVI hypothesis

Nationwide Children's Hospital chosen as a BCR for TCGA

Brazilian researchers perform autopsy study to examine the causes H1N1 death

U.S. Congress approves $1.6 million for AdMeTech Foundation's research program

Prolonged exposure to higher levels of pollutants can lead to hospitalization for pneumonia

New drug to stop cancer cells from growing and to stimulate immune system to destroy cancer cells found

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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