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Research shows how dietary essential fatty acids can help treat Alzheimer’s, other diseases

Understanding how dietary essential fatty acids work may lead to effective treatments for diseases and conditions such as stroke, Alzheimer's disease, age-related macular degeneration, Parkinson's disease and other retinal and neurodegenerative diseases.

18 Jul 2017

Researchers uncover new mechanism that promotes growth of blood vessels in tumors

Cancer cells have an enormous need for oxygen and nutrients. Therefore, growing tumors rely on the simultaneous growth of capillaries, the fine branching blood vessels that form a supply network for them.

18 Jul 2017

Adding estrogen in the brain may improve health in obese menopausal women

Researchers at the University of Cincinnati (UC) have found that adding estrogen in the brain may improve health in obese females after menopause.

18 Jul 2017

Dietary shift from high-fat foods to low-fat diet causes withdrawal-like symptoms in mice

Researchers have found that mice fed a palatable high-fat diet experience stress responses that resemble drug withdrawal when their food is switched to a low-fat diet.

18 Jul 2017

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

Moffitt Cancer Center researchers launched a first of its kind study comparing the long-term benefits of radiation therapy in women with breast cancer either before surgery (neoadjuvant) or after surgery (adjuvant).

17 Jul 2017

CNIC research holds potential to improve current cancer immunotherapy strategies

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have investigated how different subtypes of essential immune-response cells called CD8+ T lymphocytes cooperate to mount a stronger anti-tumor response.

17 Jul 2017

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a novel mechanism behind resistance to angiogenesis inhibitors - drugs that fight cancer by suppressing the formation of new blood vessels.

14 Jul 2017

Ground-breaking new breast cancer drugs have manageable toxicity profile for most patients

A ground-breaking new class of oral drugs for treating breast cancer, known as cyclin-dependent kinase (CDK) inhibitors, are generally well-tolerated, with a manageable toxicity profile for most patients.

13 Jul 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

Bone metastasis-targeting drug shows potential as new therapeutic strategy for osteosarcoma

The treatment of osteosarcoma, the most common tumor of bone, is challenging. A study led by The University of Texas MD Anderson Cancer Center found a drug known as bone metastasis-targeting peptidomimetic (BMTP-11) has potential as a new therapeutic strategy for this devastating illness.

13 Jul 2017

New study links hepatic inflammation to western diet

A new study in The American Journal of Pathology reports that mice fed a Western diet, which is high in fat and sugar, resulted in hepatic inflammation, especially in males. Moreover, liver inflammation was most pronounced in Western diet-fed male mice that also lacked farnesoid x receptor (FXR), a bile acid receptor.

12 Jul 2017

UIC researchers identify enzyme that triggers corneal inflammation

One of the symptoms of herpes simplex virus-1 infection of the eye is lingering inflammation of the cornea – the clear outer layer of the eyeball.

11 Jul 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

Benefit of ICDs may be uncertain with cumulative use of effective medications, study shows

Medication, including beta-blockers, may be so effective in reducing the risk of sudden death in heart failure that the overall benefit of implantable cardioverter-defibrillators (ICDs) may be uncertain.

7 Jul 2017

Novel small molecule tracer for PET imaging spots blood clots

Blood clots in veins and arteries can lead to heart attack, stroke, and pulmonary embolism, which are major causes of mortality.

6 Jul 2017

Loss of smell linked to weight loss in mice despite same food intake, study reveals

Experiments conducted at the University of California, Berkeley, suggest that the odor of food has a direct link with how the body processes the calories. The new study conducted on mice published in the first week of July in the journal Cell Metabolism implicates that the ability to detect the smell of food is related to whether the calories are burnt rather than stored.

6 Jul 2017

Sense of smell may play key role in how the body deals with calories

Our sense of smell is key to the enjoyment of food, so it may be no surprise that in experiments at the University of California, Berkeley, obese mice who lost their sense of smell also lost weight.

5 Jul 2017

Study opens new range of therapeutic options for patients with atypical Rett syndrome

A translational, multicenter study carried out by research groups of the Bellvitge Biomedical Research Institute, San Juan de Dios Hospital, the University of Barcelona, Clinic Hospital, the University of Vic, Santa Creu i Sant Pau Hospital and the thematic area of Rare Diseases, has unveiled the potential of D-serine -- a dietary supplement -- to improve the neuronal function of a patient with a mutation of the glutamate receptors associated to atypical Rett syndrome with severe encephalopathy.

4 Jul 2017

Researchers uncover novel mechanism of beta-blockers in preventing progression of heart failure

Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines - substances like epinephrine and norepinephrine - which overexcite and stress the heart.

4 Jul 2017

Researchers discover differences between mice and humans in function of insulin-producing beta cells

Research from King's College in London, UK, and Lund University in Sweden could explain why diabetes drugs which have worked in animal experiments are not equally successful in humans.

4 Jul 2017

Receptor News and Research

Research shows how dietary essential fatty acids can help treat Alzheimer’s, other diseases

Researchers uncover new mechanism that promotes growth of blood vessels in tumors

Adding estrogen in the brain may improve health in obese menopausal women

Dietary shift from high-fat foods to low-fat diet causes withdrawal-like symptoms in mice

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

CNIC research holds potential to improve current cancer immunotherapy strategies

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

Ground-breaking new breast cancer drugs have manageable toxicity profile for most patients

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Bone metastasis-targeting drug shows potential as new therapeutic strategy for osteosarcoma

New study links hepatic inflammation to western diet

UIC researchers identify enzyme that triggers corneal inflammation

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Benefit of ICDs may be uncertain with cumulative use of effective medications, study shows

Novel small molecule tracer for PET imaging spots blood clots

Loss of smell linked to weight loss in mice despite same food intake, study reveals

Sense of smell may play key role in how the body deals with calories

Study opens new range of therapeutic options for patients with atypical Rett syndrome

Researchers uncover novel mechanism of beta-blockers in preventing progression of heart failure

Researchers discover differences between mice and humans in function of insulin-producing beta cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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