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Machine learning may predict zoonotic potential of viral genomes

Most emerging infectious diseases of humans (like COVID-19) are zoonotic – caused by viruses originating from other animal species. Identifying high-risk viruses earlier can improve research and surveillance priorities.

28 Sep 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021

Hamilton and Rhinostics Reinvent Rapid Swab-Based Sample Workflows from Collection to Processing

Hamilton Company and Rhinostics are combining their respective strengths to improve the speed and quality of nasal and nasopharyngeal sample workflows.

From Hamilton Process Analytics 28 Sep 2021

Study shows link between smoking and COVID-19 severity, death

Smoking is highly likely to worsen the severity of COVID-19 and the risk of dying from the infection, finds a large UK Biobank study published online in the respiratory journal Thorax.

28 Sep 2021

Researchers create an integrated pipeline for performing genetic screening studies

Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools to use, and how to interpret their results. So, a team of scientists and engineers at Harvard's Wyss Institute for Biologically Inspired Engineering, Harvard Medical School (HMS), and the MIT Media Lab decided to make one.

28 Sep 2021

Research reveals nucleolar RNA interference based on C. elegans as a model organism

A research group led by Prof. GUANG Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. FENG Xuezhu from the First Affiliated Hospital of USTC, revealed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism. The study was published in Nuclear Acids Research.

28 Sep 2021

New 'reporter viruses' make it easier to observe SARS-CoV-2 in real time

A version of SARS-CoV-2, the virus that causes COVID-19 disease, has been successfully modified to glow brightly in cells and animal tissues, providing a real-time way to track the spread and intensity of viral infection as it happens in animal models, researchers at Texas Biomedical Research Institute report in the journal The Proceedings of the National Academy of Sciences.

27 Sep 2021

Mayo Clinic internist advocates a comprehensive approach to breast cancer prevention

A commentary by Mayo Clinic Cancer Center researchers published in the Journal of Clinical Oncology Practice suggests that advances in breast cancer prevention research have resulted in new and innovative opportunities to modify breast cancer risk and potentially reduce breast cancer incidence and mortality.

27 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

Research reveals new evolutive mechanism of bacteria that expands pathogenic potential

A group of nine researchers has just published new findings on the mechanisms that regulate how bacteria from the Staphylococcus aureus genus transfer genetic material, awarding them greater pathogenic virulence and resistance to antibiotics.

27 Sep 2021

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division.

25 Sep 2021

Research explores the evolution and function of human growth hormone receptor gene

A new study delves into the evolution and function of the human growth hormone receptor gene and asks what forces in humanity's past may have driven changes to this vital piece of DNA.

25 Sep 2021

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

As mRNA-based SARS-CoV-2 vaccines are deployed to protect hundreds of millions of people across the world and point the way to end the deadly global COVID-19 pandemic, the University of Pennsylvania scientists whose prescient discovery science effort laid the foundation for swift vaccine development have been awarded the 2021 Lasker~DeBakey Clinical Medical Research Award.

24 Sep 2021

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Data from early clinical trials presented at the ESMO Congress 2021 suggest that new anticancer treatments are on the horizon, with a clear emphasis on precision medicine.

24 Sep 2021

Cardiotoxic effects of common chemotherapy drug could be prevented

Harmful side effects from a common chemotherapy drug could be the result of a single mutation, according to a study published in Cell Stem Cell.

24 Sep 2021

Trained computer program can aid physicians in accurately diagnosing breast cancer

A computer program trained to see patterns among thousands of breast ultrasound images can aid physicians in accurately diagnosing breast cancer, a new study shows.

24 Sep 2021

A daily pill to treat covid could be just months away, scientists say

Within a day of testing positive for covid-19 in June, Miranda Kelly was sick enough to be scared. At 44, with diabetes and high blood pressure, Kelly, a certified nursing assistant, was having trouble breathing, symptoms serious enough to send her to the emergency room.

24 Sep 2021

Researchers identify potential approach to eliminate race from equations to estimate kidney function

Researchers have identified an approach to remove race from equations used to estimate a person's kidney function. These equations have been criticized for potentially perpetuating racial health disparities. The findings, reported September 23 in the New England Journal of Medicine, are expected to inform National Kidney Foundation–American Society of Nephrology Task Force guidelines on evaluating kidney function.

24 Sep 2021

Researchers identify two subtypes of metastatic prostate cancer

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment, information that could one day guide physicians in treating patients with the therapies best suited to their disease.

24 Sep 2021

COVID-19 vaccination and lactation

A new study evaluates the presence of antibodies in breastmilk and the immune responses of lactating women after vaccination of the COVID-19 vaccine.

23 Sep 2021

Genetic News and Research

Machine learning may predict zoonotic potential of viral genomes

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

Hamilton and Rhinostics Reinvent Rapid Swab-Based Sample Workflows from Collection to Processing

Study shows link between smoking and COVID-19 severity, death

Researchers create an integrated pipeline for performing genetic screening studies

Research reveals nucleolar RNA interference based on C. elegans as a model organism

New 'reporter viruses' make it easier to observe SARS-CoV-2 in real time

Mayo Clinic internist advocates a comprehensive approach to breast cancer prevention

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

Research reveals new evolutive mechanism of bacteria that expands pathogenic potential

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Research explores the evolution and function of human growth hormone receptor gene

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Cardiotoxic effects of common chemotherapy drug could be prevented

Trained computer program can aid physicians in accurately diagnosing breast cancer

A daily pill to treat covid could be just months away, scientists say

Researchers identify potential approach to eliminate race from equations to estimate kidney function

Researchers identify two subtypes of metastatic prostate cancer

COVID-19 vaccination and lactation

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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