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How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Researchers investigate a predictive tool for the progression of rheumatoid arthritis

Predicting the future may be beyond our grasp, but what about predicting disease progression? Researchers in Japan have delved into the human genome to investigate a predictive tool for the progression of rheumatoid arthritis (RA), an inflammatory autoimmune disease showing progressive joint damage.

7 Mar 2022

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Researchers from Columbia Engineering, Fiocruz's Center for Technological Development in Health and the Oswaldo Cruz Institute in Brazil, Memorial Sloan Kettering Cancer Center, and Rockefeller University recently reported that, by combining inhibitors of polymerases and exonucleases--enzymes that allow SARS-CoV-2 to reproduce--they were able to reduce SARS-CoV-2 replication 10 times more than when using just the polymerase inhibitors.

7 Mar 2022

Delta and Omicron coinfections identified in France

A new study shows both the Omicron and Delta variants were able to infect patients with healthy immune function.

7 Mar 2022

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Many people aspire to live longer, healthier lives. A researcher at Baylor College of Medicine, Dr. Rajagopal Sekhar, associate professor of medicine in the section of endocrinology, diabetes and metabolism, has been studying aging for the past 20 years to better understand its biological underpinnings and develop nutritional strategies to promote healthy aging.

7 Mar 2022

New, highly promising strategy to overcome a key cause of cancer deaths

A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them.

7 Mar 2022

Protein C News and Research

How have human organoids been used in research to study SARS-CoV-2?

Researchers investigate a predictive tool for the progression of rheumatoid arthritis

Study reveals the potential of novel antiviral drug combinations to stop COVID-19 spread

Delta and Omicron coinfections identified in France

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

New, highly promising strategy to overcome a key cause of cancer deaths

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Study provides new insights into the communication of bacteria with their host

Specific variant of the HLA-DPB1 gene linked with poor response to allergen immunotherapy

Clinical outcomes of regdanvimab usage in patients with mild to moderate COVID-19

Impact of humoral responses in COVID-19

Study explores differentially expressed immune genes for COVID-19 patient stratification

Current progress in SARS-CoV-2 vaccine candidates

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

Exploring biomedical literature and clinical trial records to identify new drug combinations for COVID-19 treatment

Reduced cognitive efficacy and cardiovascular changes in patients post-COVID-19 recovery

Severity-dependent immune mechanisms in the cerebrospinal fluid and plasma of COVID-19 patients

Binding efficacy of SARS-CoV-2 S1 specific salivary antibodies to the Omicron and Delta variants

Diabetes and the mTOR pathway in COVID-19 patients

MondoA protein delays cellular senescence and promotes longevity

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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