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Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Researchers assess the efficacy of 8G3, a B-cell neutralizing antibody against SARS-CoV-2 variants, including the most recent Omicron variant.

3 Mar 2022

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

A new study has focused on developing a novel anti-SARS-CoV-2 therapy using HTA directed against the human host DEAD-box RNA helicase.

3 Mar 2022

Infection with Omicron sub-lineage BA.1 protects from reinfection against BA.2 sub-lineage and vice-versa

Researchers found that infection with one Omicron sub-lineage of SARS-CoV-2 induces strong protection against reinfection with the other Omicron sub-lineage.

3 Mar 2022

Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

The discrepancy between preclinical advances in breast cancer immunotherapy and poor patient outcomes is rooted in the limitations of current breast cancer models. These models often fail to mimic complex interactions between cancer cells and key immune cells present in the tumor microenvironment.

3 Mar 2022

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

A recent study analyzes IFNa subtypes for their therapeutic potential against SARS-CoV-2 and identified the underlying immune signatures and mechanisms.

3 Mar 2022

Research uncovers a new molecular interaction mechanism for SARS-CoV2

The virus causing the current COVID-19 pandemic is the SARS-CoV-2. Soon after the pandemic outbreak in 2019, the ACE-2 protein, which is present on some of our cells´ surface, was identified as the receptor facilitating host cell viral entry.

3 Mar 2022

Study finds new benchmark for measuring the risk of death from heart surgery

A large international study has found an important new benchmark for measuring the risk of death for patients undergoing heart surgery, of which there are two million adults a year globally.

2 Mar 2022

Scientists identify new biomarkers that can be used as predictive tools of deep space flight risks

An international team of scientists has found new biomarkers that can be used for diagnostic purposes and potentially as predictive tools of the risks associated with deep space flight.

2 Mar 2022

Novel MRI approach can identify brain cell damage in people at early stages of Alzheimer's

Alzheimer's disease usually is diagnosed based on symptoms, such as when a person shows signs of memory loss and difficulty thinking.

2 Mar 2022

Sugar-decorated proteins in mucus could prevent SARS-CoV-2 viruses from spreading from surfaces

Early in the pandemic, many people fastidiously disinfected surfaces because laboratory studies predicted that SARS-CoV-2 could be easily transmitted in this way.

2 Mar 2022

How effective is mRNA vaccination in multiple myeloma patients?

In a new study, researchers have been investigating the protection offered by the SARS-CoV-2 vaccine in patients suffering from multiple myeloma.

2 Mar 2022

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Researchers evaluated the synergistic activity of drugs acting against non-structural protein 1 of SARS-CoV-2 to decrease the viral infectivity.

2 Mar 2022

Dual therapeutic potential of zapnometinib against COVID-19

Researchers assessed the impact of the drug zapnometinib on human immune response against coronavirus disease 2019.

2 Mar 2022

Similarities between SARS-CoV-2 and human retroelements explored

A new study investigated the similarities between SARS-CoV-2 and human retroelements.

2 Mar 2022

Antigenic differences between Omicron BA.1 and BA.2 SARS-CoV-2 variants

A new study identifies the antigenic differences that exist between the Omicron BA.2 and BA.1 variants.

2 Mar 2022

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

In a recent study an immunoPET technique that the authors were using to analyze SIV was adapted to evaluate the spatiotemporal dynamics of SARS-CoV-2 infection in a rhesus macaque model.

2 Mar 2022

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Researchers from different countries performed a meta-analysis of real-world cross-cohorts and provided an association of the gut microbiome with immune checkpoint inhibitors response in patients with advanced melanomas.

2 Mar 2022

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

The current study discusses a reliable ELISA that can detect three isotypes of antibody against three SARS-CoV-2 antigens.

2 Mar 2022

Understanding the evolutionary mutational patterns of chronic SARS-CoV-2 infection

In a new study, researchers elucidated the factors driving adaptive evolution in chronic SARS-CoV-2 infections.

2 Mar 2022

Protein C News and Research

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

8G3 broad-spectrum antibody effective against all SARS-CoV-2 variants, including Omicron

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

Infection with Omicron sub-lineage BA.1 protects from reinfection against BA.2 sub-lineage and vice-versa

Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

Research uncovers a new molecular interaction mechanism for SARS-CoV2

Study finds new benchmark for measuring the risk of death from heart surgery

Scientists identify new biomarkers that can be used as predictive tools of deep space flight risks

Novel MRI approach can identify brain cell damage in people at early stages of Alzheimer's

Sugar-decorated proteins in mucus could prevent SARS-CoV-2 viruses from spreading from surfaces

How effective is mRNA vaccination in multiple myeloma patients?

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Dual therapeutic potential of zapnometinib against COVID-19

Similarities between SARS-CoV-2 and human retroelements explored

Antigenic differences between Omicron BA.1 and BA.2 SARS-CoV-2 variants

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

Understanding the evolutionary mutational patterns of chronic SARS-CoV-2 infection

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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