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HRT reduces risk of breast cancer in women with BRCA mutations after ovary removal

Women with the BRCA1 or BRCA2 gene mutations, which are linked to a very high risk of breast and ovarian cancer, can safely take hormone-replacement therapy (HRT) to mitigate menopausal symptoms after surgical removal of their ovaries, according to new research from the Perelman School of Medicine at the University of Pennsylvania which will be presented Monday, June 6 during the American Society for Clinical Oncology's annual meeting.

4 Jun 2011

YM reports updated interim results from CYT387 Phase I/II study on myelofibrosis

YM BioSciences Inc., today reported updated interim safety and efficacy results from the Phase I/II study of its JAK1/JAK2 inhibitor, CYT387, for the treatment of myelofibrosis.

4 Jun 2011

Battelle, Perma-Fix sign exclusive option agreement to make medical isotopes

Perma-Fix Environmental Services, Inc. today announced it has signed an exclusive option agreement with Battelle, which operates Pacific Northwest National Laboratory for the U.S. Department of Energy, to license technology from PNNL for use with Perma-Fix's proprietary process to safely and cost-effectively produce Molybdenum-99 (Mo-99), which is used to make Technetium 99m (Tc-99m).

4 Jun 2011

ARIAD's ponatinib initial Phase 1 study data on acute myeloid leukemia to be presented at ASCO 2011

ARIAD Pharmaceuticals, Inc. today announced initial clinical findings on ponatinib in patients with advanced acute myeloid leukemia (AML).

3 Jun 2011

Media outlets examine case of man cured of HIV, leukemia through bone marrow transplant

In a special report, Reuters examines the case of Timothy Ray Brown, who was cured of HIV and leukemia after undergoing "a bone marrow transplant using cells from a donor with a rare genetic mutation, known as CCR5 delta 32," which researchers knew conveyed resistance to HIV infection.

3 Jun 2011

Hip strengthening exercises reduce patellofemoral pain, improve female runners' gaits

Hip strengthening exercises performed by female runners not only significantly reduced patellofemoral pain -- a common knee pain experienced by runners -- but they also improved the runners' gaits, according to Indiana University motion analysis expert Tracy Dierks.

3 Jun 2011

Experts from 16 national osteoporosis societies to meet in Dubai for IOF event

Online registration and abstract submission is now open for the largest bone meeting of 2011 to be held in the Middle-East and Africa region.

2 Jun 2011

Free online WHO Fracture Risk Assessment Tool now available as version 3.3

The WHO Fracture Risk Assessment Tool (FRAX-) is an important new calculation tool, available free online at http://www.shef.ac.uk/FRAX, that is being used by a steadily increasing number of physicians around the world to calculate a patient's 10-year probability of fracture based on scientifically validated risk factors.

2 Jun 2011

PCF funds 14 new Creativity Awards for advanced prostate cancer research

The Prostate Cancer Foundation today announced that it has funded 14 new Creativity Awards for advanced prostate cancer research. These two-year awards are designed to support innovative research ideas that have the potential to achieve breakthroughs for improved prostate cancer diagnosis and treatment.

2 Jun 2011

Adipose-derived stem cell procedure restores skull defects after brain surgery

Stem cells derived from abdominal fat—used along with a synthetic bone grafting material—are a potentially valuable new approach to repairing skull defects after brain surgery, according to a study in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

2 Jun 2011

Adaptimmune announces opening of Phase I/II clinical trial in multiple myeloma

Adaptimmune announced that it has opened a Phase I/II, dual site, two-cohort, open-label clinical trial in multiple myeloma at the University of Maryland and the University of Pennsylvania testing its enhanced T cell receptor T cell therapy.

1 Jun 2011

Scans, hospital infections at heart of new quality issues

A new diagnostic imaging test that can detect plaque in the arteries of the heart is not an efficient tool for screening people not experiencing symptoms of heart disease, a recent study found.

1 Jun 2011

$Femoral neck BMD and FRAX scores are useful for assessing fracture risk in diabetes patients$

Femoral neck BMD and FRAX scores are useful for assessing fracture risk in diabetes patients

Use of established fracture prediction methods in older patients with type 2 diabetes mellitus (DM) found that scores from these methods were associated with hip and nonspine fracture risk, and a certain score associated with higher risk of fracture compared to persons without DM, according to a study in the June 1 issue of JAMA.

1 Jun 2011

Researchers receive CTSI Award for Translational Research in Maternal, Child, and Adolescent Health.

Patricia Dickson, MD, and Jennifer Yee, MD, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) researchers, will be honored on Thursday as recipients of the first UCLA Clinical and Translational Science Institute's (CTSI) Award for Translational Research in Maternal, Child, and Adolescent Health.

1 Jun 2011

Surgeons minimize amputation rate among patients injured in Haitian earthquake

A team of plastic and orthopedic surgeons achieved a high success rate in limb salvage—minimizing the need for amputations—among patients injured in last year's devastating earthquake in Haiti, reports a study in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

1 Jun 2011

Sleep loss reduces healthy young man's testosterone levels

Cutting back on sleep drastically reduces a healthy young man's testosterone levels, according to a study published in the June 1 issue of the Journal of the American Medical Association.

1 Jun 2011

Centocor Ortho Biotech, AVEO sign license deal to develop, commercialize RON-targeted antibodies

AVEO Pharmaceuticals, Inc. today announced it has entered into an exclusive license agreement with Centocor Ortho Biotech Inc. for the worldwide development and commercialization of AVEO's internally-discovered antibodies targeting the RON receptor.

1 Jun 2011

YM BioSciences' CYT387 receives European Commission positive opinion for Orphan Drug Designation

YM BioSciences Inc., today announced that it has received positive opinions from the Committee for Orphan Medicinal Products of the European Commission to grant Orphan Medicinal Product Designation to its JAK1/JAK2 inhibitor, CYT387, for the treatment of primary myelofibrosis, post-polycythaemia vera myelofibrosis and post-essential thrombocythaemia myelofibrosis.

31 May 2011

AACE applauds legislation for preservation of access to osteoporosis testing for Medicare beneficiaries

The American Association of Clinical Endocrinologists (AACE) applauds the introduction of legislation in both the U.S. House of Representatives and the U.S. Senate that will preserve patient access to osteoporosis testing and treatment services under the Medicare program.

27 May 2011

Study: Cardiovascular disease may be under treated in rheumatoid arthritis patients

Results of a study, involving 98,454 patients demonstrated that at 30 days following their first heart attack, RA patients were approximately 20% less likely to be prescribed standard MI treatments, such as statins and betablockers, compared to healthy patients.

27 May 2011

Bone News and Research

HRT reduces risk of breast cancer in women with BRCA mutations after ovary removal

YM reports updated interim results from CYT387 Phase I/II study on myelofibrosis

Battelle, Perma-Fix sign exclusive option agreement to make medical isotopes

ARIAD's ponatinib initial Phase 1 study data on acute myeloid leukemia to be presented at ASCO 2011

Media outlets examine case of man cured of HIV, leukemia through bone marrow transplant

Hip strengthening exercises reduce patellofemoral pain, improve female runners' gaits

Experts from 16 national osteoporosis societies to meet in Dubai for IOF event

Free online WHO Fracture Risk Assessment Tool now available as version 3.3

PCF funds 14 new Creativity Awards for advanced prostate cancer research

Adipose-derived stem cell procedure restores skull defects after brain surgery

Adaptimmune announces opening of Phase I/II clinical trial in multiple myeloma

Scans, hospital infections at heart of new quality issues

Femoral neck BMD and FRAX scores are useful for assessing fracture risk in diabetes patients

Researchers receive CTSI Award for Translational Research in Maternal, Child, and Adolescent Health.

Surgeons minimize amputation rate among patients injured in Haitian earthquake

Sleep loss reduces healthy young man's testosterone levels

Centocor Ortho Biotech, AVEO sign license deal to develop, commercialize RON-targeted antibodies

YM BioSciences' CYT387 receives European Commission positive opinion for Orphan Drug Designation

AACE applauds legislation for preservation of access to osteoporosis testing for Medicare beneficiaries

Study: Cardiovascular disease may be under treated in rheumatoid arthritis patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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