Immune System News and Research

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Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous -- their own -- immune cells to create large amounts of fillable nanovesicles to deliver drugs to tumors in mice.

13 Mar 2018

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Biofilms are surface-attached communities of bacterial or fungal cells that are enmeshed in an extensive extracellular matrix which makes them more resistant to both antibiotics and the immune system.

13 Mar 2018

Researchers find specific cellular structures that orchestrate rapid immunologic memory

With every infection or vaccination, memory cells form that the body uses to remember the pathogen. This has been known for decades - but the structure of this cellular immunologic memory has previously proven impossible to pin down.

9 Mar 2018

Cycling keeps the body young and healthy

Not surprisingly, a new study has shown that keeping active can keep the body young and healthy. The study comes from the researchers at the University of Birmingham and King's College London who were looking at the health of older adults who had been exercising most of their adult lives. The research has been reported in two papers published this week in the journal Aging Cell.

8 Mar 2018

Study seeks to examine whether gut bacteria cause brain dysfunction in sepsis patients

Surviving a critical illness is no small feat, but it's only half the battle for many patients. Serious complications can still result after an illness appears to have cleared.

8 Mar 2018

New study examines origin of cryptococcosis within the central nervous system

A particular fungal infection is responsible for more than 220,000 cases of cryptococcosis worldwide each year in people with HIV and AIDS, with nearly 181,000 of those resulting in death.

8 Mar 2018

Researchers identify new mechanism to disrupt HIV latency

HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.

8 Mar 2018

Slow-release injectable gel boosts toxicity of cancer-fighting immunotherapy drugs

An immunotherapy drug embedded in a slow-release hydrogel invented at Rice University in collaboration with the University of Texas Health Science Center at Houston appears to be highly effective at killing cancer cells.

7 Mar 2018

Researchers reveal new molecular target to help ease asthma symptoms

Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A -- or VEGFA -- plays a major role in the inflammation and airway obstruction associated with asthma.

7 Mar 2018

FDA approves new tests to detect tickborne parasite in human plasma and whole blood samples

The U.S. Food and Drug Administration today approved the Imugen Babesia microti Arrayed Fluorescent Immunoassay, for the detection of antibodies to Babesia microti (B. microti) in human plasma samples, and the Imugen Babesia microti Nucleic Acid Test (NAT), for the detection of B. microti DNA in human whole blood samples.

7 Mar 2018

FDA approves new antiretroviral medication for patients with multidrug-resistant HIV

Today, the U.S. Food and Drug Administration approved Trogarzo (ibalizumab-uiyk), a new type of antiretroviral medication for adult patients living with HIV who have tried multiple HIV medications in the past (heavily treatment-experienced) and whose HIV infections cannot be successfully treated with other currently available therapies (multidrug resistant HIV, or MDR HIV).

6 Mar 2018

One-month antibiotic regimen to prevent TB as safe, effective as nine-month therapy for HIV patients

A one-month antibiotic regimen to prevent active tuberculosis (TB) disease was at least as safe and effective as the standard nine-month therapy for people living with HIV, according to the results of a large international clinical trial.

6 Mar 2018

Research shows how interaction between nervous and immune systems occurs in lung infections

When the body is fighting infection, the immune system kicks into high gear. But emerging evidence hints at the involvement of another, rather surprising, player in this process: the nervous system.

5 Mar 2018

Young men recovering from flu have increased risk of developing Guillain-Barré syndrome

This year's flu season has been one of the worst in recent memory causing thousands of people to be hospitalized. The virus can be particularly dangerous for young men who can experience nerve damage caused by the body's response to the flu.

2 Mar 2018

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune system to fight cancer.

2 Mar 2018

Antibiotic use may affect efficacy of cancer immunotherapies

Antibiotic use is known to have a near-immediate impact on our gut microbiota and long-term use may leave us drug-resistant and vulnerable to infection.

2 Mar 2018

Virus-like particle could translate into new vaccine for cancer treatment

Michigan State University scientists are engineering a virus-like particle, known as Qβ, that will generate anti-cancer immune responses in the body and potentially be used as a new vaccine for the treatment of cancer.

2 Mar 2018

Research shows how viruses inactivate immune system, causing cancer

It's no new news that viruses cause cancer. For example, human papillomavirus causes almost all of the more than 500,000 annual worldwide cases of cervical cancer.

2 Mar 2018

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Dr. Alicia G. Arroyo, have identified a function of a protease that could be targeted for the treatment of some infections and even tumor metastasis.

2 Mar 2018

Parasitic tapeworm could someday help prevent or treat pediatric IBD

New research suggests that parasitic worms could someday help prevent or treat pediatric inflammatory bowel disease (IBD). The study, published ahead of print in the American Journal of Physiology-Gastrointestinal and Liver Physiology, was chosen as an APSselect article for March.

2 Mar 2018

Immune System News and Research

Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Researchers find specific cellular structures that orchestrate rapid immunologic memory

Cycling keeps the body young and healthy

Study seeks to examine whether gut bacteria cause brain dysfunction in sepsis patients

New study examines origin of cryptococcosis within the central nervous system

Researchers identify new mechanism to disrupt HIV latency

Slow-release injectable gel boosts toxicity of cancer-fighting immunotherapy drugs

Researchers reveal new molecular target to help ease asthma symptoms

FDA approves new tests to detect tickborne parasite in human plasma and whole blood samples

FDA approves new antiretroviral medication for patients with multidrug-resistant HIV

One-month antibiotic regimen to prevent TB as safe, effective as nine-month therapy for HIV patients

Research shows how interaction between nervous and immune systems occurs in lung infections

Young men recovering from flu have increased risk of developing Guillain-Barré syndrome

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

Antibiotic use may affect efficacy of cancer immunotherapies

Virus-like particle could translate into new vaccine for cancer treatment

Research shows how viruses inactivate immune system, causing cancer

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Parasitic tapeworm could someday help prevent or treat pediatric IBD

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