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A digital CRISPR-based method for quick detection and absolute quantification of SARS-CoV-2

In a recent medRxiv* preprint manuscript, researchers from Singapore and the United States report the development of a digital CRISPR method for the sensitive, specific, and rapid detection of viral nucleic acids at a constant temperature, which could be exploited for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Nov 2020

New Zealand case study shows room for improvement in genomic sequencing of COVID-19 outbreaks

Researchers in New Zealand, the United States and Australia have demonstrated the effectiveness of real-time genomic sequencing at tracking the re-emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New Zealand, in August this year.

5 Nov 2020

Fear circuit extends far beyond the amygdala, research shows

When a frightful creature startles you, your brain may activate its fear-processing circuitry, sending your heart racing to help you escape the threat.

5 Nov 2020

Genomic surveillance of yellow fever outbreak in São Paulo

Yellow fever virus is normally confined to the Amazon region, but the virus circulated in the Southeast of Brazil between 2016 and 2018, causing the worst epidemic and epizootic outbreaks there for decades.

5 Nov 2020

Researchers solve longstanding mystery about peculiar hybrid structures found in bacteria

Peculiar hybrid structures called retrons that are half RNA, half single-strand DNA are found in many species of bacteria.

5 Nov 2020

HKUST researchers identify new therapeutic targets for Alzheimer's disease

Researchers at the Hong Kong University of Science and Technology have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology.

5 Nov 2020

Super-resolution images of functioning and pathologically altered nerve cells

Three experts for super-resolution microscopy jointly want to obtain better images of functioning and pathologically altered nerve cells. The European Research Council ERC is funding them with eleven million euros.

5 Nov 2020

NIH awards grant totaling $19.5M for Down syndrome research project

Scientists and data experts are joining forces to create the world's first centralized platform for Down syndrome researchers to share, access, and analyze data.

5 Nov 2020

Argonne supports the largest analysis of COVID-19 genome sequences in the U.S.

Argonne computational resources supported the largest comprehensive analysis of COVID-19 genome sequences in the U.S. and helped corroborate growing evidence of a protein mutation.

5 Nov 2020

Smart actuating materials can transform biomedical technologies

Bio-compatible electrostrictive materials will play a leading role in the future generation of medical micro-electro-mechanical systems (MEMS).

5 Nov 2020

Novel approach for modeling spread of infectious disease

The rapid spread of SARS-CoV-2 across the world despite the early shutdown of borders and the cessation of international travel has sparked interest and given rise to changes in knowledge regarding the spread of infections.

4 Nov 2020

Study shows brilacidin strongly inhibits SARS-CoV-2 in laboratory cell lines

A recent study by US researchers reveals that brilacidin, a small synthetic molecule with peptide-like properties, exerts potent in vitro antiviral activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – both as a standalone treatment and in combination with FDA-approved remdesivir. The study is currently available on the bioRxiv preprint server.

4 Nov 2020

Chikungunya can infect central nervous system and impair cognitive, motor functions

A study conducted by an international team of researchers with FAPESP's support shows that infection by chikungunya virus can produce even more severe manifestations than the typical symptoms of the disease, such as acute fever, headache, rash, and intense joint and muscle pain.

4 Nov 2020

Lions and tigers and anteaters? US scientists scan the menagerie for COVID

As COVID-19 cases surge in the U.S., one Texas veterinarian has been quietly tracking the spread of the disease — not in people, but in their pets.

4 Nov 2020

SARS-CoV-2 mutations becoming more contagious

A team of researchers working with Scott Wesley Long from Houston Methodist Hospital and colleagues from Texas, New York, and Illinois studied the patterns of genetic mutations of SARS CoV-2 and its impact on the second wave of infections worldwide.

3 Nov 2020

AI speech processing framework detects inaudible COVID-19 cough

Now, a team of researchers at the Massachusetts Institute of Technology (MIT) has found that asymptomatic people may differ from those who are healthy in the way they cough. The differences are inaudible to the human ear but can be detected by artificial intelligence (AI).

3 Nov 2020

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Some of the principal treatments for osteoporosis, denosumab, zoledronate and calcium, could have a protective effect against COVID-19 in patients who take them, specifically a 30 to 40% reduction in the rate of infection, according to the results of a joint study by Hospital del Mar, the Hospital del Mar Medical Research Institute (IMIM), Pompeu Fabra University and the Pere Virgili Health Park.

3 Nov 2020

Rapid generation of divergent synthetic antibodies against SARS-CoV-2 in a cell-free engineering platform

In a groundbreaking bioRxiv paper, a research group from the Massachusetts Institute of Technology (MIT), Harvard University and Howard Hughes Medical Institute in the US engineered antibodies against the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein by using a novel approach. In doing so, they also identified more than 800 predicted binder families.

3 Nov 2020

Researchers identify a novel vulnerability in advanced prostate cancer

Researchers at the University of Bern led an international team that has identified a novel vulnerability in advanced prostate cancer that is no longer responding to hormonal therapy.

3 Nov 2020