Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Wnt signaling pathway plays a role in diabetic retinopathy

A group led by Dr. Jian-xing Ma at The University of Oklahoma Health Sciences Center, Oklahoma City, OK has demonstrated that the Wnt signaling pathway plays a role in diabetic retinopathy.

26 Nov 2009

Wnt and EGFR signaling pathways interact to promote tumor cell invasion and metastasis

Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers from The University of Texas M. D. Anderson Cancer Center report in the Nov. 25 issue of Molecular Cell.

26 Nov 2009

Scientists offer first genetic proof of new and rational treatment for osteoporosis

The so-called RANK protein and the molecule that binds to it, the RANK ligand or RANKL, form a focus of the work of Josef Penninger, director of the Institute of Molecular Biotechnology (IMBA) in Vienna. In 1999 his group deleted the RANKL gene from mice and showed that the RANK/RANKL system was the "master regulator" governing bone loss (Kong et al. 1999 Nature 402, 304-309).

26 Nov 2009

Low-temperature plasma prototype devices as bactericidal cocktails

MRSA (methicillin-resistant Staphylococcus Aureus) and other drug-resistant bacteria could face annihilation as low-temperature plasma prototype devices have been developed to offer safe, quick, easy and unfailing bactericidal cocktails.

26 Nov 2009

Aegis Breast 3.0 that offers powerful real-time 4D image processing to be launched

Sentinelle Medical Inc., a leading manufacturer of breast MRI coils and advanced visualization software launches a suite of new leading edge clinical applications on its Aegis(TM) medical imaging software platform at this year's Radiological Society of North America (RSNA) annual meeting in Chicago, Nov. 30 - Dec. 5, 2009 (Booth 5800, Hall A).

26 Nov 2009

UGR researchers provide early diagnosis of ARMD and keratitis

Researchers from the UGR have provided an early diagnosis of certain ocular diseases that are very common today, such as age-related macular degeneration and keratitis, by applying an existing optical technique that, nevertheless, had never before been used for this purpose.

25 Nov 2009

Study may pave way for potential drug targets in lung cancer treatment

Researchers from Boston University School of Medicine (BUSM) and the Boston University Biomedical Engineering Department have identified a number of proteins whose activation allows them to distinguish between cancer and normal cells with almost 97 percent accuracy.

25 Nov 2009

Community-based program proves to be successful in reducing skin infections in Australian aboriginal children

A community-based program aimed at reducing the burden of skin disease across remote communities in Australia's Northern Territory has been successful according to a study published November 24 in the open-access journal PLoS Neglected Tropical Diseases.

25 Nov 2009

Study shows 95 percent of radiation oncologists use FDG-PET, MRI and 4DCT to locate cancer

A recent study shows that 95 percent of radiation oncologists use advanced imaging techniques such as positron emission tomography (FDG-PET), magnetic resonance imaging (MRI), and 4-dimensional computed tomography (4DCT) for target delineation (to locate the tumor and other areas at risk for having cancer), according to an article in the December issue of the Journal of the American College of Radiology, (JACR, www.jacr.org).

25 Nov 2009

Studies demonstrate clinical utility of Given Imaging's PillCam SB capsule endoscopy

Given Imaging Ltd., the global leader in patient-friendly GI diagnostic and monitoring solutions, today announced three new studies that demonstrate the clinical utility of PillCam SB capsule endoscopy in providing physicians with critical information on how they manage and/or diagnose intestinal disorders. These novel studies were carried out in pediatric patients with gastrointestinal symptoms, including children with known or suspected Crohn's disease.

24 Nov 2009

Research suggests common oral bacterium may exacerbate autoimmune disease

Current research suggests that a common oral bacterium may exacerbate autoimmune disease. The related report by Nichols et al, "Unique Lipids from a Common Human Bacterium Represent a New Class of TLR2 Ligands Capable of Enhancing Autoimmunity," appears in the December 2009 issue of The American Journal of Pathology.

23 Nov 2009

Study examines how dietary restriction and high-caloric diet influence biochemical responses

Researchers at Mount Sinai School of Medicine set out to address a question that has been challenging scientists for years: How do dietary restriction-and the reverse, overconsumption-produce protective effects against aging and disease?

23 Nov 2009

BMI and co-morbidity do not explain racial survival disparity in colon cancer patients

A new study by University of Alabama at Birmingham (UAB) researchers shows that body-mass index (BMI) and co-existing medical conditions (co-morbidity) do not explain the decreased survival observed among African-Americans compared to Caucasians who also have colon cancer. The study is published online Nov. 23 in Cancer, a journal of the American Cancer Society.

23 Nov 2009

Given Imaging introduces new PillCam system at GASTRO 2009 Conference

Given Imaging Ltd., the global leader in capsule endoscopy, today announced the launch of its second-generation PillCam® COLON capsule at the Gastro 2009 Conference taking place in London. Like Given Imaging's other capsule endoscopes, PillCam® SB and PillCam® ESO, PillCam COLON could be a more patient-friendly tool for imaging the gastrointestinal tract.

23 Nov 2009

New research examines screen time in home-based and center-based child care settings

In a new study, the amount of television viewed by many young children in child care settings doubles the previous estimates of early childhood screen time, with those in home-based settings watching significantly more on average than those in center-based daycares.

23 Nov 2009

Discovery holds promise in fighting cancer, AIDS and autoimmune disorders

Researchers at the University of Alabama at Birmingham (UAB) have uncovered the genetic identity of a cellular receptor for the immune system's first-response antibody, a discovery that sheds new light on infection control and immune disorders.

21 Nov 2009

FISH technology accurate in measuring the HER-2 receptor in human breast tumors

The debate on how to select patients who will respond best to costly drug treatments for aggressive breast cancer now favors fluorescence in situ hybridization (FISH) to measure the HER-2 receptor found in human breast tumors, according to a leading pathologist presenting at the Association for Molecular Pathology annual meeting.

20 Nov 2009

CVS/pharmacy kicks off its fundraiser for St. Jude Children's Research Hospital's annual campaign

CVS/pharmacy kicks off its annual in store fundraiser for the sixth year to support the St. Jude Children's Research Hospital Thanks and Giving campaign, beginning this Sunday and running through December 12. CVS/pharmacy store colleagues will encourage customers to add $1 to their purchase at the register to support the lifesaving research of St. Jude, one of the world's premier centers for the research and treatment of pediatric cancer and other catastrophic childhood diseases.

20 Nov 2009

GERD is an immune-mediated injury and not the result of acid burn, says new study

Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study.

20 Nov 2009

AcroMetrix introduces the OptiQual HPV Genotype Panel

AcroMetrix, a leading manufacturer of quality control material for clinical diagnostic and blood testing laboratories, announced today the launch of its OptiQual HPV Genotype Panel. Designed to help clinical laboratories comply with CLIA guidelines for qualitative molecular assays that detect Human Papillomavirus (HPV), this addition to AcroMetrix’s line of women’s health products can assist laboratorians with the validation and verification of their molecular HPV tests.

19 Nov 2009

Pathology News and Research

Further Reading

Wnt signaling pathway plays a role in diabetic retinopathy

Wnt and EGFR signaling pathways interact to promote tumor cell invasion and metastasis

Scientists offer first genetic proof of new and rational treatment for osteoporosis

Low-temperature plasma prototype devices as bactericidal cocktails

Aegis Breast 3.0 that offers powerful real-time 4D image processing to be launched

UGR researchers provide early diagnosis of ARMD and keratitis

Study may pave way for potential drug targets in lung cancer treatment

Community-based program proves to be successful in reducing skin infections in Australian aboriginal children

Study shows 95 percent of radiation oncologists use FDG-PET, MRI and 4DCT to locate cancer

Studies demonstrate clinical utility of Given Imaging's PillCam SB capsule endoscopy

Research suggests common oral bacterium may exacerbate autoimmune disease

Study examines how dietary restriction and high-caloric diet influence biochemical responses

BMI and co-morbidity do not explain racial survival disparity in colon cancer patients

Given Imaging introduces new PillCam system at GASTRO 2009 Conference

New research examines screen time in home-based and center-based child care settings

Discovery holds promise in fighting cancer, AIDS and autoimmune disorders

FISH technology accurate in measuring the HER-2 receptor in human breast tumors

CVS/pharmacy kicks off its fundraiser for St. Jude Children's Research Hospital's annual campaign

GERD is an immune-mediated injury and not the result of acid burn, says new study

AcroMetrix introduces the OptiQual HPV Genotype Panel

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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