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Acid reflux can kill certain cancer cells

A University of Central Florida chemist has come up with a unique way to kill certain cancer cells - give them acid reflux.

7 Mar 2013

Study investigates how cancer cells 'hijack' platelets

A new research study has investigated how cancer cells 'hijack' blood cells known as platelets, enabling cancer to spread around the body and promoting the growth of new tumours, it was reported today at the annual Royal College of Surgeons in Ireland (RCSI) Research Day.

7 Mar 2013

mTORC2 plays key role in regulating memory formation

Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your brain has taken a short-term memory - the introduction - and converted it into a long-term one.

7 Mar 2013

Global Blood Therapeutics, Array BioPharma partner for drug discovery research

Array BioPharma Inc. and Global Blood Therapeutics today announced a multi-target drug discovery collaboration agreement to identify small molecule lead compounds targeting chronic blood-based diseases.

6 Mar 2013

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.

6 Mar 2013

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer.

6 Mar 2013

Scientists discover key biochemical step underlying heart failure

Some 5.8 million Americans suffer from heart failure, a currently incurable disease. But scientists at Temple University School of Medicine's (TUSM) Center for Translational Medicine have discovered a key biochemical step underlying the condition that could aid the development of new drugs to treat and possibly prevent it.

6 Mar 2013

EGCG in green tea controls generation of metal-associated amyloids associated with Alzheimer's

Researchers at the University of Michigan have found a new potential benefit of a molecule in green tea: preventing the misfolding of specific proteins in the brain.

6 Mar 2013

Study shows how high shear stress could cause VWF to change shape and form blood clots

New research from Rice University, Baylor College of Medicine (BCM) and the Puget Sound Blood Center (PSBC) has revealed how stresses of flow in the small blood vessels of the heart and brain could cause a common protein to change shape and form dangerous blood clots.

6 Mar 2013

Insight into how protein synthesis and degradation help regulate delicate ballet of cell division

Biochemists at the University of Massachusetts Amherst including assistant professor Peter Chien recently gained new insight into how protein synthesis and degradation help to regulate the delicate ballet of cell division. In particular, they reveal how two proteins shelter each other in "mutually assured cleanup" to insure that division goes smoothly and safely.

5 Mar 2013

Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

Sanford-Burnham Medical Research Institute and 60- Pharmaceuticals, LLC, have entered into a partnership to test furin, a human proteinase, as a drug target for the treatment of dengue fever, one of the most common infectious diseases in the tropics and subtropics.

5 Mar 2013

PsiOxus completes enrollment in MT-102 Phase II trial on cancer cachexia

PsiOxus Therapeutics, Ltd. (PsiOxus), a development stage biotechnology company, has completed patient enrollment for its Phase II clinical trial to study MT-102, a small molecule therapeutic for the treatment of cancer cachexia.

4 Mar 2013

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex to target with a drug since it is also crucial to the healthy functioning of many immune cells in the body, not just B cells gone bad.

4 Mar 2013

Study identifies two gene mutations that lead to death of nerve cells in ALS

A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

4 Mar 2013

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.

2 Mar 2013

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus.

2 Mar 2013

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for under-served medical needs in neurology and cardiology, announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).

1 Mar 2013

Molecule News and Research

Acid reflux can kill certain cancer cells

Study investigates how cancer cells 'hijack' platelets

mTORC2 plays key role in regulating memory formation

Global Blood Therapeutics, Array BioPharma partner for drug discovery research

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Scientists discover key biochemical step underlying heart failure

EGCG in green tea controls generation of metal-associated amyloids associated with Alzheimer's

Study shows how high shear stress could cause VWF to change shape and form blood clots

Insight into how protein synthesis and degradation help regulate delicate ballet of cell division

Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

PsiOxus completes enrollment in MT-102 Phase II trial on cancer cachexia

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

Study identifies two gene mutations that lead to death of nerve cells in ALS

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

EpiCept fourth quarter revenue decreases to $0.1 million

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

MenB bacterium uses Adhesin Complex Protein to stick to human cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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