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Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

The Ivy Brain Tumor Center at Barrow Neurological Institute, the largest early-phase drug development program for brain cancer in the world, announced results from their Phase 0/1 clinical trial of ribociclib plus everolimus in patients with high-grade glioma (HGG).

13 Sep 2021

Neutrophil extracellular traps boost the bacterial killing power of macrophages

Like a spider trapping its prey, our immune system cells cooperate to capture and "eat" bacteria.

12 Sep 2021

Combination of chemotherapy and immune checkpoint inhibitors shows promise in NSCLC patients with untreated brain metastases

Treatment with atezolizumab plus carboplatin and pemetrexed was safe and yielded promising brain progression-free survival in patients with nonsquamous non-small cell lung cancer with untreated and asymptomatic brain metastases.

12 Sep 2021

USC Stevens INI launches a $3 million study to solve some puzzles about Parkinson's disease

The USC Mark and Mary Stevens Neuroimaging and Informatics Institute (USC Stevens INI), part of the Keck School of Medicine of USC, has launched a $3 million study that will unite researchers and data from 20 countries to answer some of the most pressing questions about Parkinson's disease (PD).

11 Sep 2021

New precision-guided sterile insect technique designed to control disease-spreading mosquitoes

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

11 Sep 2021

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

For men with "low-risk" prostate cancer initially managed with active surveillance, cancer-related factors such as tumor grade and size are key risk factors for conversion to active treatment, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association.

10 Sep 2021

FB-EVAR is safe and effective for treatment of aortic aneurysms, study shows

A recent study revealed that endovascular repair of complex aortic aneurysms using fenestrated and branched endografts provides a safe and effective alternative to open surgical repair, with the lowest ever reported mortality rate in this patient population, according to researchers at The University of Texas Health Science Center at Houston and Memorial Hermann Heart and Vascular Institute Aortic Center.

10 Sep 2021

New research project aims to better understand the brain basis of cognitive control

Are you able to start a task and stick with it, all the way through, ignoring the temptations of the internet or the sudden realization that you should probably do the laundry?

10 Sep 2021

Washington University School of Medicine receives $7 million to investigate how human genome works

Washington University School of Medicine in St. Louis has received a $7 million grant from the National Institutes of Health to help lead national efforts to investigate how variations in the human genome sequence affect how the genome functions.

9 Sep 2021

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

Sequencing the human genome - a feat accomplished in 2003 - provided the list of ingredients that make up a human being, but not the instructions that explain how those ingredients are used by each cell type to create complex "meals."

9 Sep 2021

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure.

9 Sep 2021

Food science principles help scientists to understand inner workings of cellular compartments

Johns Hopkins Medicine researchers report that food science principles have helped them determine how unusual droplets within cells stay organized and avoid dissolving into the rest of the cell's gelatinous interior.

9 Sep 2021

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

9 Sep 2021

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Duke University and the University of North Carolina at Chapel Hill have been awarded funds from the National Institutes of Health to establish a prestigious Alzheimer's Disease Research Center (ADRC), part of a federally-funded national network of similar centers.

9 Sep 2021

Discovery about cellular 'batteries' could open the door to better treatments for many diseases

A top exercise researcher at the University of Virginia School of Medicine has revealed how our bodies ensure the proper functioning of the powerhouses of our cells.

9 Sep 2021

Self-correcting genetic mutations may protect patients with shortened telomeres from blood cancers

People with rare disorders that cause shortened telomeres — protective caps that sit at the end of chromosomes — may be more likely to have blood cancers such as leukemia or myelodyplastic syndrome.

8 Sep 2021

“Batman Sam” fights cancer with care from Johns Hopkins Children’s Center

"What the heck is happening?" recalls Melissa Southward, the mother of now-three-year-old Sam, when he started having nose bleeds and developed a yellowish skin color in August 2020.

8 Sep 2021

Advancements in the diagnosis and treatment of prostate cancer are saving more lives

Prostate cancer is the most common type of cancer among men in the United States aside from skin cancer, according to the Centers for Disease Control and Prevention.

8 Sep 2021

Genetically predicted COVID-19 linked to blood clots, thrombophlebitis and circulatory diseases

Research led by Queen Mary University of London associates genetically determined COVID-19 susceptibility with increased blood clot events in leg and lungs, thrombophlebitis and circulatory diseases.

8 Sep 2021

Infections during adolescence linked to increased risk of developing MS later in life

According to a new study, severe infections during adolescence may lead to an increased risk of contracting MS later in life. "We're talking mainly about brain and spinal cord infections, but also respiratory tract infections," says Scott Montgomery, professor at örebro University.

8 Sep 2021

Genetic News and Research

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

Neutrophil extracellular traps boost the bacterial killing power of macrophages

Combination of chemotherapy and immune checkpoint inhibitors shows promise in NSCLC patients with untreated brain metastases

USC Stevens INI launches a $3 million study to solve some puzzles about Parkinson's disease

New precision-guided sterile insect technique designed to control disease-spreading mosquitoes

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

FB-EVAR is safe and effective for treatment of aortic aneurysms, study shows

New research project aims to better understand the brain basis of cognitive control

Washington University School of Medicine receives $7 million to investigate how human genome works

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Food science principles help scientists to understand inner workings of cellular compartments

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Discovery about cellular 'batteries' could open the door to better treatments for many diseases

Self-correcting genetic mutations may protect patients with shortened telomeres from blood cancers

“Batman Sam” fights cancer with care from Johns Hopkins Children’s Center

Advancements in the diagnosis and treatment of prostate cancer are saving more lives

Genetically predicted COVID-19 linked to blood clots, thrombophlebitis and circulatory diseases

Infections during adolescence linked to increased risk of developing MS later in life

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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