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Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

How does the immune system remember and recognize viral invaders it has encountered in the past? A trio of newly published studies of people infected with SARS-CoV-2, vaccinated against the virus or both, are providing tantalizing new clues about the factors that influence the speed and magnitude of the immune system's response to subsequent infection with variants of SARS-CoV-2.

19 May 2022

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded approximately $577 million to establish nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern.

18 May 2022

Study identifies cancer biomarkers based on a type of genetic modification

Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that can be consistently reproduced and are easily analyzed with limited patient specimens.

18 May 2022

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Human beings, like most organisms, are constantly exposed to alternating colder or warmer temperatures.

17 May 2022

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

A new study has focussed on determining the clonality and levels of SARS-CoV-2-reactive CD4+ T cells in CCPs post-vaccination.

12 May 2022

World's first Focused Ultrasound Cancer Immunotherapy Center could revolutionize cancer care

UVA Health and the Charlottesville-based Focused Ultrasound Foundation today announced the launch of the Focused Ultrasound Cancer Immunotherapy Center, the world's first center dedicated specifically to advancing a focused ultrasound and cancer immunotherapy treatment approach that could revolutionize 21st-century cancer care.

11 May 2022

Simulating molecular dynamics of SARS-CoV-2 spike variants in the locked conformation

Researchers retrieved the first-ever sequenced spike (S) protein structures of the original Wuhan-Hu 1 SARS-CoV-2 strain, the Alpha, Delta, Delta-plus variants, and Omicron sub-variants BA.1 and BA.2 and compared their structural and molecular level variations.

10 May 2022

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a silver lining, leading to novel treatment opportunities.

9 May 2022

Evidence of croup associated with SARS-CoV-2

A new study published in the Journal of Pediatric Infectious Diseases Society aimed to characterize the clinical features of SARS-CoV-2-associated croup among children presenting to the ED during the phase when Omicron variant transmission was high.

9 May 2022

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

A new study published in the New England Journal of Medicine has discussed the efficacy and safety profile of the ZF2001 vaccine in adults, based on a randomized, placebo-controlled, multinational, double-blind phase 3 trial.

9 May 2022

Infection with SARS-CoV-2 results in antibodies against common colds

A study published in the journal Science Advances uses electron microscopy-based polyclonal epitope mapping (EMPEM) methodology to elucidate the spike epitopes of β-HCoV targeted by preexisting serum antibodies and compares them to the epitopes targeted by antibodies elicited by SARS-CoV-2 infection using electron microscopy-based polyclonal epitope mapping (EMPEM) methodology.

8 May 2022

ACNAP-EuroHeartCare Congress 2022: Latest evidence on how to optimize cardiovascular care

Discover how patients with heart disease can live well, be healthy, and live longer at ACNAP-EuroHeartCare Congress 2022, a scientific congress of the European Society of Cardiology (ESC).

6 May 2022

Mitosis in moss plants could be far more similar to animal cell division than previously thought

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in this process, known as mitosis, is being researched by Prof. Dr. Ralf Reski and Dr. Elena Kozgunova from the University of Freiburg in a joint effort with Prof. Dr. Gohta Goshima from Nagoya University.

6 May 2022

A guide to help you keep up with the omicron subvariants

Two years into the coronavirus pandemic, Americans can be forgiven if they've lost track of the latest variants circulating nationally and around the world. We've heard of the alpha, beta, gamma, delta, and omicron variants, but a new Greek-letter variant hasn't come onto the scene in almost half a year.

6 May 2022

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature".

5 May 2022

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Researchers analyzed the inhibition of stress granules formation in cells infected by the human common cold coronavirus HCOV-OC43 and SARS-CoV-2.

5 May 2022

Higher vaccination coverage associated with lower rates of population-level COVID-19 mortality and incidence in the US

By using data representing 80% of the US population, researchers have found that increased vaccination coverage against COVID-19 can be linked to a reduced incidence of cases and deaths.

2 May 2022

Novel therapy using nitric oxide may be an efficient and safe way to treat multiple metabolic diseases

A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet.

29 Apr 2022

The added value of adequate immune fitness to the existing approaches to pandemic preparedness

Researchers described two studies, the CLOFIT retrospective study and the COTEST real-time study, that investigated if maintaining adequate immune fitness could significantly add to the current strategies of preparedness for COVID-19 and other pandemics.

28 Apr 2022

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Researchers assessed the binding pocket of linoleic acid, an essential free-fatty acid in the receptor-binding domains of the spike protein of beta-coronaviruses.

26 Apr 2022

Cold News and Research

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

Study identifies cancer biomarkers based on a type of genetic modification

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

World's first Focused Ultrasound Cancer Immunotherapy Center could revolutionize cancer care

Simulating molecular dynamics of SARS-CoV-2 spike variants in the locked conformation

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

Evidence of croup associated with SARS-CoV-2

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

Infection with SARS-CoV-2 results in antibodies against common colds

ACNAP-EuroHeartCare Congress 2022: Latest evidence on how to optimize cardiovascular care

Mitosis in moss plants could be far more similar to animal cell division than previously thought

A guide to help you keep up with the omicron subvariants

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Higher vaccination coverage associated with lower rates of population-level COVID-19 mortality and incidence in the US

Novel therapy using nitric oxide may be an efficient and safe way to treat multiple metabolic diseases

The added value of adequate immune fitness to the existing approaches to pandemic preparedness

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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