DNA Sequencing News and Research

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DNAzymes, gold nanoparticles and disease detection: an interview with Dr Chan and Kyryl Zagorovsky, University of Toronto

Gold nanoparticles are tiny spherical particles made out of gold atoms with sizes on nanometre scale. This is around 1,000 times smaller than the thickness of human hair.

23 Apr 2013

Stratified Medicine Scotland Innovation Centre (SMS-IC) receives funding from the Scottish Funding Council

The University of Glasgow is set to boost its contribution to global medical research and the Scottish economy following the announcement of funding to build a major research centre.

23 Apr 2013

Abnormal protein translation leads to Fragile X ataxia, study finds

A bizarre twist on the usual way proteins are made may explain mysterious symptoms in the grandparents of some children with mental disabilities.

19 Apr 2013

North American scientists chart new territory in immunity research

Cracking the DNA code for a complex region of the human genome has helped 14 North American scientists, including five at Simon Fraser University, chart new territory in immunity research.

19 Apr 2013

Three missense variants of BRCA1 gene linked to breast or ovarian cancer risk, study shows

Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute and the Catalan Institute of Oncology conducted a functional and structural study of seven missense variants of the BRCA1 gene concluding that three of these variants are pathogenic, linked to the risk of suffering breast or ovarian cancer.

19 Apr 2013

CRISPR helps some bacteria evade mammalian immune system

CRISPR, a system of genes that bacteria use to defend themselves against viruses, has been found to be involved in helping some bacteria evade the mammalian immune system.

18 Apr 2013

Researchers find three new regions of genome that influence obesity in people of African descent

The largest genetic search for "obesity genes" in people of African ancestry has led to the discovery of three new regions of the human genome that influence obesity in these populations and others.

16 Apr 2013

New data on use of PBD dimers as warheads in ADCs presented at AACR annual meeting

Spirogen, a leading oncology-focused company developing DNA sequence targeted agents, and BioAtla LLC, a San Diego headquartered antibody therapeutics developer, today announced new data on the use of pyrrolobenzodiazepine (PBD) dimers as warheads in antibody drug conjugates (ADCs) at the annual meeting of the American Association for Cancer Research (AACR) in Washington, DC.

11 Apr 2013

Incidence of late-onset Alzheimer disease higher among African Americans

In a meta-analysis of data from nearly 6,000 African Americans, Alzheimer disease was significantly associated with a gene that have been weakly associated with Alzheimer disease in individuals of European ancestry, although additional studies are needed to determine risk estimates specific for African Americans, according to a study in the April 10 issue of JAMA, a Genomics theme issue.

11 Apr 2013

Gene variations can predispose people to chemotherapy-induced peripheral neuropathy

Seemingly benign differences in genetic code from one person to the next could influence who develops side effects to chemotherapy, a Mayo Clinic study has found.

10 Apr 2013

Researchers use single-cell genome sequencing approach to analyze microbe from biofilm in hospital

A team of researchers led by scientists from the J. Craig Venter Institute (JCVI) has published a study outlining the recovery and genomic analysis, using single-cell genomic techniques, of a periodontal pathogen, Porphyromonas gingivalis, from a hospital sink.

6 Apr 2013

Individualized genomic analysis allows for tailored cancer treatment, new drug research

Just like a massive iceberg jutting out of the ocean, many of cancer's genetic underpinnings remain hidden under the surface, impossible to predict or map from above.

6 Apr 2013

China reports 2 more cases of H7N9; Researchers continue to investigate transmission routes

"China has found two more cases of a new strain of bird flu and one of the victims has died, state media said on Wednesday, bringing to nine the number of confirmed human infections from the previously unknown flu type," Reuters reports (Blanchard/Kelland, 4/3).

5 Apr 2013

New screening procedure determines animal, plant, and microbial substances in foodstuffs

Scientists at the Institute of Molecular Genetics, Genetic Security Research and Consulting at Johannes Gutenberg University Mainz (JGU) have developed a novel screening procedure that provides for highly sensitive, quantifiable analysis of animal, plant, and microbial substances present in foodstuffs.

28 Mar 2013

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

Researchers shed new light on role of methylation in gene expression

Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed.

28 Mar 2013

First multi-gene DNA sequencing test launched for cancer patients

The first multi-gene DNA sequencing test that can help predict cancer patients' responses to treatment has been launched in the National Health Service, thanks to a partnership between scientists at the University of Oxford and Oxford University Hospitals NHS Trust.

26 Mar 2013

Study uncovers new relationship between nuclear architecture, gene activity

Every time a cell divides it makes a carbon copy of crucial ingredients, including the histone proteins that are responsible for spooling yards of DNA into tight little coils.

25 Mar 2013

Genetic testing services for rare neurological disorders launched by Athena Diagnostics

Athena Diagnostics, a leader in neurological diagnostics, today announced the clinical availability of new genetic tests to aid the detection of several rare neurological disorders, including hereditary neuropathy, neuromuscular disease, epilepsy and certain movement disorders. The lab-developed tests are available through Athena Diagnostics, a business of Quest Diagnostics (NYSE:DGX), the world’s leading provider of diagnostic information services.

From Quest Diagnostics 19 Mar 2013

TGen to present latest research about multiple myeloma at free public conference

The Translational Genomics Research Institute will present its latest research about a cancer known as multiple myeloma at a free public conference hosted by the Arizona Myeloma Network.

15 Mar 2013

DNA Sequencing News and Research

DNAzymes, gold nanoparticles and disease detection: an interview with Dr Chan and Kyryl Zagorovsky, University of Toronto

Stratified Medicine Scotland Innovation Centre (SMS-IC) receives funding from the Scottish Funding Council

Abnormal protein translation leads to Fragile X ataxia, study finds

North American scientists chart new territory in immunity research

Three missense variants of BRCA1 gene linked to breast or ovarian cancer risk, study shows

CRISPR helps some bacteria evade mammalian immune system

Researchers find three new regions of genome that influence obesity in people of African descent

New data on use of PBD dimers as warheads in ADCs presented at AACR annual meeting

Incidence of late-onset Alzheimer disease higher among African Americans

Gene variations can predispose people to chemotherapy-induced peripheral neuropathy

Researchers use single-cell genome sequencing approach to analyze microbe from biofilm in hospital

Individualized genomic analysis allows for tailored cancer treatment, new drug research

China reports 2 more cases of H7N9; Researchers continue to investigate transmission routes

New screening procedure determines animal, plant, and microbial substances in foodstuffs

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Researchers shed new light on role of methylation in gene expression

First multi-gene DNA sequencing test launched for cancer patients

Study uncovers new relationship between nuclear architecture, gene activity

Genetic testing services for rare neurological disorders launched by Athena Diagnostics

TGen to present latest research about multiple myeloma at free public conference

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