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New study reveals mechanism of inflammation in lupus

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

15 Oct 2024

Genetics identified as key factor in gout development

A major international study has found gout is a chronic illness where genetics is a major cause, rather than lifestyle choices of the sufferer.

15 Oct 2024

Social isolation linked to micronutrient deficiencies in older adults

Older adults in the UK who are socially isolated are more likely to have an insufficient intake of key micronutrients such as vitamin C and vitamin B6, increasing their risk of health problems, according to a new study led by UCL (University College London) researchers.

15 Oct 2024

Study: Fear of cancer recurrence is common among adult survivors of childhood cancer

A new study by Concordia researchers suggests that one-third of adult survivors of childhood cancer experience a fear of cancer recurrence so severe that it can seriously impact their daily lives.

15 Oct 2024

Study reveals how Alzheimer's may cause brain damage in two distinct phases

Alzheimer's disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

15 Oct 2024

Understanding how the hippocampus discriminates social threat from safety

How do we distinguish threat from safety? It's a question important not just in our daily lives, but for human disorders linked with fear of others, such as social anxiety or post-traumatic stress disorder (PTSD).

15 Oct 2024

Scripps Research identifies binding site on challenging cancer protein

Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate.

15 Oct 2024

SU2C announces grants to support cutting-edge research in a variety of cancers

Stand Up To Cancer (SU2C) today announced grants to several teams of leading cancer investigators in support of cutting-edge research in a variety of cancers including head and neck, pediatric, pancreatic, breast, rectal and gastro-esophageal cancers, as well as research focused on how the microbiome communicates with the immune system.

15 Oct 2024

New method aims to improve lung transplant access for hard-to-match candidates

Researchers at Cleveland Clinic and Case Western Reserve University (CWRU) have developed a new method that could potentially help provide better access to lung transplant for transplant candidates who are hard to match because of their blood type or height.

15 Oct 2024

Extrachromosomal DNA in more aggressive cancers could be targets for future therapies

Research published in Nature Genetics on Oct.14, by Yale Cancer Center researchers at Yale School of Medicine, found a higher concentration of a specific kind of DNA — extrachromosomal or ecDNA — in more aggressive and advanced cancers that could mark them as targets for future therapies.

15 Oct 2024

Compassionate approaches needed for miscarriage management in Canada

Miscarriage, or early pregnancy loss, can have devastating emotional effects, but it is poorly managed in Canada.

15 Oct 2024

Genomic findings shed light on ancient Japanese population origins

A joint research group led by Jonghyun Kim and Jun Ohashi of the University of Tokyo has demonstrated that the majority of immigration to the Japanese Archipelago in the Yayoi and Kofun periods (between 3000 BCE and 538 CE) came from the Korean Peninsula.

14 Oct 2024

Report outlines path to halve premature deaths by 2050

Since 1970, 37 countries have cut the probability of their citizens dying before they reach age 70 in half, a milestone that signals the remarkable progress many countries have made in preventing and treating disease.

14 Oct 2024

New gene therapy offers hope in combatting childhood obesity

According to the Centers for Disease Control, nearly 20% of children and teens are considered obese.

14 Oct 2024

Uncovering human-specific genes linked to brain development and disorders

The human brain's remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities.

14 Oct 2024

New vial size could save Medicare millions on Alzheimer's drug

Medicare could save up to 74% of the money lost from discarded Alzheimer's drug lecanemab by the simple introduction of a new vial size that would reduce the amount of unused medication that is thrown away, new research suggests.

14 Oct 2024

Naloxone use by non-medical bystanders on the rise, but not fast enough

Use of a lifesaving drug to reverse opioid drug overdoses is growing, but not fast enough. That's according to new research in JAMA Network Open from The Ohio State University College of Medicine, College of Public Health and the National Registry of Emergency Medical Technicians.

14 Oct 2024

De novo antibody protein sequencing reveals novel functional and neutralizing antibodies post-SARS-CoV-2 vaccination

Rapid Novor has published a study that highlights the power of combining de novo antibody protein sequencing with conventional proteomics to uncover functional and neutralizing antibodies in human plasma following SARS-CoV-2 vaccination.

From Rapid Novor Inc 14 Oct 2024

Study highlights delays in care for pediatric trauma patients

Severely injured children who are brought to an emergency medical department by their parents or carers are often not seen as quickly as those who arrive at the hospital via ambulance, according to findings presented at the European Emergency Medicine Congress on 14th October 2024.

14 Oct 2024

Computational tools unlock the secrets of the genome

In collaboration with the International Conference on Research in Computational Molecular Biology (RECOMB), Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.

13 Oct 2024