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Subtle genetic shifts in brain enzyme offer clues to human evolution

The evolutionary success of our species may have hinged on minute changes to our brain biochemistry after we diverged from the lineage leading to Neanderthals and Denisovans about half a million years ago.

5 Aug 2025

Spear Bio announces strategic partnership with Bio-Techne to accelerate the deployment of its next-generation immunoassay technology

Spear Bio, a biotechnology company pioneering homogeneous ultrasensitive immunoassay technology, is pleased to announce a strategic distribution partnership with Bio-Techne Corporation, a global leading provider of innovative reagents, instruments, and solutions for life-science research and clinical diagnostics.

From Spear Bio 5 Aug 2025

Spear Bio launches next generation ultrasensitive immunoassay solution SPEAR UltraDetect™ to transform neurodegenerative disease research

Spear Bio, a biotechnology company pioneering homogeneous ultrasensitive immunoassay technology, today announced the commercial launch of its SPEAR UltraDetect™ immunoassay solution. It delivers unparalleled sensitivity, specificity, precision, and scalability for robust biomarker measurement.

From Spear Bio 5 Aug 2025

LptM protein revealed as essential to outer membrane stability in bacteria

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria.

4 Aug 2025

New insights reveal how sugar metabolism protects neurons from degeneration

Unlike most cells in the human body, neurons-the functional cells of our nervous system-cannot typically replace themselves with healthy copies after being damaged.

4 Aug 2025

Scientists reveal how rare gene mutations drive schizophrenia risk

Researchers analyzed the largest exome-sequencing dataset to date and identified new rare coding variants and genes linked to schizophrenia risk. The study highlights converging genetic pathways, implicating chromatin organization and GABAergic signaling in schizophrenia neurobiology.

4 Aug 2025

HIV trial points to semaglutide as a new anti-aging contender

Once-weekly semaglutide significantly slowed epigenetic aging in adults with HIV-associated lipohypertrophy, as measured by multiple DNA methylation clocks in a randomized controlled trial. These exploratory findings suggest GLP-1 receptor agonists could impact biological aging but require further validation in broader populations.

4 Aug 2025

Weight loss doubles when eating minimally processed foods over ultra-processed alternatives

When given nutritionally matched diets, participants lost twice as much weight eating minimally processed foods compared to ultra-processed foods, suggesting that cutting down on processing could help to sustain a healthy weight long term, finds a new clinical trial led by researchers at UCL and UCLH.

4 Aug 2025

Programmable Chromosome Engineering systems enable precise DNA manipulations

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

4 Aug 2025

New drug combo outperforms Tamiflu in fighting deadliest flu strains

A surprising new drug combo—including a compound found in chocolate—has outperformed Tamiflu in fighting the flu, according to a study published in PNAS.

4 Aug 2025

Creatine in your diet may benefit your digestive system

Findings suggest dietary creatine from meat may alleviate chronic constipation, with stronger effects observed in men and those without certain health issues.

4 Aug 2025

New research unveils vast influence of B vitamins on health and disease

Eight essential nutrients make up the suite of B vitamins also known as the B complex. Researchers from Tufts University and elsewhere have revealed that these B vitamins influence a vast spectrum of human health and disease, including cognitive function, cardiovascular health, gastric bypass recovery, neural tube defects, and even cancer.

4 Aug 2025

Johns Hopkins uncovers protein's unexpected role in brain signaling

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with genetically engineered mice.

4 Aug 2025

Can your diet and health change your breast milk? Review uncovers the key maternal and birth factors

This review highlights how maternal, obstetrical, and neonatal factors influence the energy and macronutrient content of breast milk. The findings underscore significant variability in milk composition, with implications for tailored nutritional support in early life.

3 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Key protein found to guide melanoma cells during spread

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body.

1 Aug 2025

Synthetic torpor moves closer to real-world medical use

Nature is often the best model for science. For nearly a century, scientists have been trying to recreate the ability of some mammals and birds to survive extreme environmental conditions for brief or extended periods by going into torpor, when their body temperature and metabolic rate drop, allowing them to preserve energy and heat.

1 Aug 2025

Bioengineered dressing achieves rapid hemostasis and accelerated wound healing

In a study published in Advanced Materials on July 22, a team led by Dr. ZHONG Chao and Dr. AN Bolin from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, collaborating with Dr. LIU Yan from Ruijin Hospital Aﬃliated to Shanghai Jiao Tong University School of Medicine, developed an innovative bacterial cellulose (BC)-based hemostatic dressing that enables rapid and sustained bleeding control.

1 Aug 2025