Ribonucleic Acid News and Research

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A review of vaccines against the respiratory syncytial virus

This study reviewed the epidemiology, molecular characteristics, populations affected by the virus, and vaccines against RSV.

3 Nov 2022

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

In a recent study posted to the medRxiv* preprint server, researchers in the United States investigated the source of an enigmatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)-like spike (S) protein strain detected in wastewater but not in clinical samples.

2 Nov 2022

Vimentin is an important co-receptor for SARS-CoV-2 infection

Vimentin functions as a co-receptor for the entry of SARS-CoV-2 into host cells to facilitate infection.

2 Nov 2022

Bivalent mRNA booster broadens humoral immunity against SARS-CoV-2 Omicron subvariants

Researchers at Emory University, Stanford University, and the National Institute of Allergy and Infectious Diseases evaluated whether bivalent coronavirus disease 2019 (COVID-19) boosters conferred protection against new Omicron subvariants.

2 Nov 2022

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Researchers in the United Kingdom evaluated a battery-operated portable air sampler that could recover severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosolized in a laboratory using a plaque assay.

2 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

Did active monitoring detect potentially elevated risk of health outcomes following BNT162b2 COVID-19 vaccination in the US pediatric population aged 5-17 years?

Researchers used a nearly real-time monitoring framework for early detection of potential safety signals following the administration of the BNT162b2 vaccine in over three million United States children aged five to 17 years.

2 Nov 2022

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

Researchers examined how imprinted SARS-CoV-2 humoral immunity drives convergent evolution in continuously emerging Omicron subvariants.

2 Nov 2022

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New research discussed the structure and life cycle of respiratory syncytial virus (RSV), the current research on the treatment and prevention of RSV infections, and the advancements in RSV mRNA vaccine technology after the surge in vaccine research during the COVID-19 pandemic.

1 Nov 2022

Exploring viral loads of SARS-CoV-2 Omicron BA.5 and BA.2 sublineages

In a new study, researchers compared the viral loads of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.5 and BA.2 sublineages.

1 Nov 2022

New research suggests booster dose of Novavax NVX-CoV2373 vaccine is effective against SARS-CoV-2 Omicron subvariants

A new study evaluated the neutralizing antibody titers against the SARS-CoV-2 Omicron variant and its sub-lineages after two and three doses of the Novavax protein nanoparticle vaccine NVX-CoV2373.

31 Oct 2022

An innovative nasal vaccine strategy to combat COVID

In a recent study published in the journal Science, researchers at Yale University developed a novel coronavirus disease 2019 (COVID-19) vaccination strategy termed 'prime and spike' (P&S) that leveraged existing systemic immunity triggered by parenteral vaccination (prime) to boost immunity at the respiratory mucosa.

31 Oct 2022

Favorable outcomes of infants born after maternal COVID-19 during pregnancy

Researchers assess the outcomes of children born to mothers infected during pregnancy with SARS-CoV-2.

30 Oct 2022

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Researchers investigated whether immunity against seasonal human coronavirus spike proteins of HKU1, OC43, NL63, or 229E could protect against SARS-CoV-2 in vitro.

28 Oct 2022

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Researchers evaluated to what extent prior infection and vaccination protected the residents and staff of the United States California state prison system from breakthrough infection by SARS-CoV-2 Omicron sub-variant B.1.1.529.

28 Oct 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

In a recent study posted to the bioRxiv* preprint server, researchers at Beth Israel Deaconess Medical Center assessed the immunogenicity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.5 bivalent messenger ribonucleic acid (mRNA) vaccine boosters.

27 Oct 2022

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Researchers explore the thermodynamic properties of the SARS-CoV-2 Omicron subvariant BA.2.75 to understand its increased transmissibility.

27 Oct 2022

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

Researchers assessed the impact of SARS-CoV-2 vaccination on the occurrence and severity of symptoms in SARS-CoV-2 Omicron-infected hospitalized patients.

27 Oct 2022

Ribonucleic Acid News and Research

A review of vaccines against the respiratory syncytial virus

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

Vimentin is an important co-receptor for SARS-CoV-2 infection

Bivalent mRNA booster broadens humoral immunity against SARS-CoV-2 Omicron subvariants

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

Did active monitoring detect potentially elevated risk of health outcomes following BNT162b2 COVID-19 vaccination in the US pediatric population aged 5-17 years?

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Exploring viral loads of SARS-CoV-2 Omicron BA.5 and BA.2 sublineages

New research suggests booster dose of Novavax NVX-CoV2373 vaccine is effective against SARS-CoV-2 Omicron subvariants

An innovative nasal vaccine strategy to combat COVID

Favorable outcomes of infants born after maternal COVID-19 during pregnancy

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

The epigenetic alterations of monocytes in severe COVID-19

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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