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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Ardea Biosciences reports results of RDEA594 Phase 2a study for hyperuricemia and gout

Ardea Biosciences, Inc. announced additional positive results from the completed first cohort of an ongoing Phase 2a, proof-of-concept study of RDEA594, its lead product candidate for the treatment of hyperuricemia and gout.

19 Oct 2009

Breakthrough discovery by scientists may lead to a new treatment for Alzheimer's Disease

A breakthrough discovery by scientists from the Mayo Clinic in Jacksonville, FL, may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques-considered a hallmark of the disease-from patients' brains.

19 Oct 2009

New chromosomal abnormality in acute lymphoblastic leukemia

Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia (ALL) that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children with Down syndrome.

19 Oct 2009

Novel HIV drug to be studied in cell cultures and patients

A $6 million, five-year federal grant to The Children's Hospital of Philadelphia Research Institute will enable researchers to investigate a novel approach in treating HIV infection---a unique class of drugs focused on developing therapies for psychological and neurological effects in AIDS.

19 Oct 2009

Physical therapists stress on definitive vestibular screenings and assessment measures for BITBI

Physical therapists are calling for definitive vestibular screenings and assessment measures for US military service members with blast-induced traumatic brain injuries (BITBI). According to a Scholarly Opinion Piece in the September issue of Physical Therapy, the scientific journal of the American Physical Therapy Association (APTA), vestibular rehabilitation must be included as part of successful treatment for those who have been injured by blasts and experience vestibular symptoms such as vertigo, gaze instability, and motion intolerance.

19 Oct 2009

International human migration needs to be factored into infectious disease policy

When people travel, bacteria and other infectious agents travel with them. As about a billion people cross international borders each year, many more billions of the bugs come along for the ride.

19 Oct 2009

Enzo Biochem to release a new catalog dealing with epigenetics and chromatin modification

Enzo Biochem, Inc. today said that its Life Sciences subsidiary will release a new catalog dealing with “Epigenetics & Chromatin Modification” at the Society for Neuroscience’s, Neuroscience 2009 conference, beginning October 17, 2009, in Chicago, Illinois.

15 Oct 2009

College of American Pathologists honours Dr. Kevin B. Dole as the 2009 Pathologist of the Year

Kevin B. Dole, MD, FCAP, was named the 2009 Pathologist of the Year at a ceremony held on October 11, 2009, in Washington DC at CAP '09 -- The Pathologists' Meeting(TM).

15 Oct 2009

Sangretech Biomedical signs amended license agreement with Bostwick Laboratories

Sangretech Biomedical LLC, a developer of dendritic cell therapies for cancer and infectious diseases, today announced it has executed an amended and restated license agreement with Bostwick Laboratories, Inc. providing Bostwick Scientific, the research division of Bostwick Laboratories, with exclusive rights to Sangretech’s dendritic cell technology in certain territories.

15 Oct 2009

UT Southwestern Medical Center awarded $15.7M NIH contract to develop a new virus database

The National Institutes of Health has awarded a $15.7 million contract to UT Southwestern Medical Center and Northrop Grumman Corp. to develop an open-access national online database and analysis resource center that will help scientists study and combat viruses such as those that cause hepatitis, encephalitis, smallpox, acute respiratory distress and dengue fever, as well as newly emerging pathogenic viruses.

15 Oct 2009

Marker genes help determine the effectiveness of targeted molecular drug regimen for treating GIST

Analysis of a small number of marker genes may determine in a matter of hours if a patient with gastrointestinal stromal tumors (GIST) would respond to a targeted molecular drug regimen. This analysis could allow clinicians to determine if they have chosen the best course of action or need to consider another alternative.

15 Oct 2009

AMP congratulates SACGHS on the publication of their DNA patenting report

The Association for Molecular Pathology (AMP) provided comments at the Secretary's Advisory Committee on Genetics, Health and Society (SACGHS) meeting on October 8. AMP opposes the patenting of all naturally occurring genetic material and has signed on as a lead plaintiff in the ACLU case challenging Myriad Genetics' patents on the BRCA 1 and BRCA 2 genes. AMP thanked SACGHS for studying how both patents and restrictive licensing limit patient access and potentially reduce the quality of tests.

15 Oct 2009

University of North Carolina awarded grant to continue research on rare disease-causing gene mutations

The University of North Carolina at Chapel Hill has been awarded a five-year, $6.2 million renewal grant to continue its work as part of the National Institutes of Health's Rare Diseases Clinical Research Network (RDCRN).

14 Oct 2009

Institute of Medicine elects researcher from The Children's Hospital of Philadelphia as its member

A prominent scientist at The Children's Hospital of Philadelphia, Thomas Curran, Ph.D., FRS, has been elected to the Institute of Medicine. Dr. Curran has long been a leading researcher in pediatric oncology.

14 Oct 2009

Brain researcher finds how the epilepsy and pain drug works

A Duke University Medical Center researcher who spent years looking for the signals that prompt the brain to form new connections between neurons has found one that may explain precisely how a well-known drug for epilepsy and pain actually works.

14 Oct 2009

Decreased expression of tumor suppressor gene PTEN transforms neurofibromas into cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center showed for the first time that the loss or decreased expression of the tumor suppressor gene PTEN plays a central role in the malignant transformation of benign nerve tumors called neurofibromas into a malignant and extremely deadly form of sarcoma.

14 Oct 2009

Kinetic Concepts to showcase its ABThera OA NPT System at the American College of Surgeons Congress

Kinetic Concepts, Inc. will feature ABThera™ Open Abdomen Negative Pressure Therapy System, the latest addition to the KCI Negative Pressure Technology Platform (NPTP), at the American College of Surgeons’ 95th Annual Clinical Congress, Oct. 11-15 in Chicago.

13 Oct 2009

New study launched to detect DNA alterations linked to sudden cardiac death in sports

The BBVA Foundation and the Cardiology Service of Madrid's Hospital Clínico San Carlos have launched a new study aimed at detecting DNA alterations linked to sudden cardiac death in sports. Genetic testing is vital if the condition is to be caught in time, since most cases are asymptomatic and hard to diagnose by other means.

13 Oct 2009

New Case Editorial Boards to promote online participation of pathologists

PathXchange.org, a global online pathology community, announced the establishment of Case Editorial Boards (CEB) for over 20 pathology subspecialties to promote online participation and to ensure quality content in the portal.

13 Oct 2009

New mouse models resembles human ALS; may provide important tool for screening new drugs

A new mouse model of amyotrophic lateral sclerosis (ALS) closely resembles humans with the paralyzing disorder, researchers at Washington University School of Medicine in St. Louis report.

13 Oct 2009

Pathology News and Research

Further Reading

Ardea Biosciences reports results of RDEA594 Phase 2a study for hyperuricemia and gout

Breakthrough discovery by scientists may lead to a new treatment for Alzheimer's Disease

New chromosomal abnormality in acute lymphoblastic leukemia

Novel HIV drug to be studied in cell cultures and patients

Physical therapists stress on definitive vestibular screenings and assessment measures for BITBI

International human migration needs to be factored into infectious disease policy

Enzo Biochem to release a new catalog dealing with epigenetics and chromatin modification

College of American Pathologists honours Dr. Kevin B. Dole as the 2009 Pathologist of the Year

Sangretech Biomedical signs amended license agreement with Bostwick Laboratories

UT Southwestern Medical Center awarded $15.7M NIH contract to develop a new virus database

Marker genes help determine the effectiveness of targeted molecular drug regimen for treating GIST

AMP congratulates SACGHS on the publication of their DNA patenting report

University of North Carolina awarded grant to continue research on rare disease-causing gene mutations

Institute of Medicine elects researcher from The Children's Hospital of Philadelphia as its member

Brain researcher finds how the epilepsy and pain drug works

Decreased expression of tumor suppressor gene PTEN transforms neurofibromas into cancer

Kinetic Concepts to showcase its ABThera OA NPT System at the American College of Surgeons Congress

New study launched to detect DNA alterations linked to sudden cardiac death in sports

New Case Editorial Boards to promote online participation of pathologists

New mouse models resembles human ALS; may provide important tool for screening new drugs

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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