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Impact of COVID-19 on children with complex underlying medical conditions

A new study concludes that children with medical complexities experienced adverse health outcomes during the COVID-19 pandemic.

8 Dec 2021

Rapid antigen detection test for SARS-CoV-2 proves more effective than expected, large study reports

In what is believed to be the largest prospective study of its kind to date - involving some 6,000 patients seen at the Baltimore Convention Center Field Hospital (BCCFH) during a 10-day period around the beginning of 2021 - researchers at Johns Hopkins Medicine, the University of Maryland Medical Center, the University of Maryland School of Medicine and four other collaborators report that a rapid antigen detection test for SARS-CoV-2, the virus that causes COVID-19, proved more effective than expected when compared with virus detection rates using the established standard test, the polymerase chain reaction (PCR) assay.

8 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

New approaches needed to address the U.S. opioid epidemic

To address the U.S. opioid epidemic, policies and guidelines have focused primarily on reducing opioid prescribing and restricting supply. Accordingly, opioid prescribing decreased 38% in the past decade.

7 Dec 2021

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

Octapharma USA today announced the U.S. Food & Drug Administration has approved cutaquig [Immune globulin, Subcutaneous (Human)-hipp, 16.5% Solution] for the treatment of pediatric patients age 2 and older with primary humoral immunodeficiency (PI). The FDA previously approved cutaquig for adults with PI.

7 Dec 2021

Smart transformable nanoparticles show promise for enhanced tumor theranostics

For more than three decades, biomedical nanomaterials have been successfully developed for the benefit of theranostics -- a compound term referring to the diagnoses and treatment of tumors.

7 Dec 2021

Cochlear implant recipients develop new bone formation that leads to long-term residual hearing loss

The majority of cochlear implant recipients develop new bone formation that adversely affects long-term hearing preservation, according to a study appearing in Radiology.

7 Dec 2021

‘Moving molecule’ therapy for severe spinal cord injury

In this interview, News-Medical speaks to Dr. Stupp about his recent research into a therapy involving dancing molecules for the treatment of severe spinal cord injury.

7 Dec 2021

Possible impact of spike protein mutations on SARS-CoV-2 Omicron variant

The current study not only analyses the mutations in the Omicron spike variant but classifies various combinations of spike mutations into groups.

7 Dec 2021

New self-administered test can find the early subtle signs of dementia sooner

Many people experience forgetfulness as they age, but it's often difficult to tell if these memory issues are a normal part of aging or a sign of something more serious

7 Dec 2021

Study finds mRNA-based COVID-19 vaccines are effective in cancer patients

The mRNA-based COVID-19 vaccines are effective at preventing infection in most cancer patients, according to a nationwide study of veterans diagnosed with cancer in the past decade.

6 Dec 2021

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

A new mouse model suggests that prior HCoV-OC43 S immunity primes neutralising antibody responses to otherwise subimmunogenic SARS-CoV-2 S exposure as well as promotes S2-targeting antibody responses.

6 Dec 2021

Novel monoclonal antibody could help revolutionize treatment of children with high-risk neuroblastoma

Survival rates increased about 20% for children with high-risk neuroblastoma enrolled in a St. Jude Children’s Research Hospital clinical trial that included a novel monoclonal antibody produced onsite. The findings appeared today in the Journal of Clinical Oncology.

6 Dec 2021

A faster, safer and more affordable technology to produce personalized cancer therapies

Cell therapy has become an indispensable part of medicine today. With this form of immunotherapy you use your own body cells as medicine to fight the disease.

6 Dec 2021

UC San Diego participates in the expansion of Parkinson’s Progression Markers Initiative

After a decade of pioneering research, the Parkinson's Progression Markers Initiative by The Michael J. Fox Foundation for Parkinson's Research will see a major expansion.

6 Dec 2021

Mutations in a crucial gene responsible for chemotherapy failure in some blood cancer patients

Mutations in a crucial gene are the key reason that chemotherapy fails in some patients with blood cancer, a study by Nanyang Technological University, Singapore (NTU Singapore) and Singapore General Hospital (SGH) has found.

6 Dec 2021

COVID-19 vaccines shown to reduce SARS-CoV-2 infection rate in cancer patients

A study recently published in the journal JAMA Oncology has stated that coronavirus disease 2019 (COVID-19) vaccines are more than 55% effective in reducing the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in cancer patients.

5 Dec 2021