Kidney News and Research

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TF2 bispecific antibody pretargeted therapy prolongs survival in animal model of human colonic cancer

Immunomedics, Inc., a biopharmaceutical company focused on developing monoclonal antibodies to treat cancer and other serious diseases, today announced that pretargeted therapy with TF2, a bispecific antibody against carcinoembryonic antigen (CEA) and a small peptide, delayed tumor growth and prolonged survival in an animal model of human colonic cancer.

10 Jun 2010

University of Missouri researchers to investigate cadmium's potential for causing endometrial cancer

McDonald's announced a recall recently of 12 million "Shrek"-themed collectible glasses because traces of the toxic metal cadmium were found in them. Cadmium, a silver-white metal, is found in many substances, including certain foods and batteries, and experts believe that it might be a carcinogen. In a new study, University of Missouri researchers will investigate cadmium's potential for causing endometrial cancer.

10 Jun 2010

Researchers receive funding to study care processes in patients beginning dialysis

Researchers at the University of Cincinnati and the Cincinnati Department of Veterans Affairs (VA) Medical Center have received funding to study the care processes that lead to placement of arteriovenous fistulas in patients beginning dialysis.

9 Jun 2010

Low-income African-Americans have higher risk of CKD: Research

African Americans with incomes below the poverty line have a significantly higher risk of chronic kidney disease than higher-income African-Americans or whites of any socioeconomic status, research led by scientists at Johns Hopkins and the National Institute on Aging shows. Conducted in a racially and socioeconomically diverse sample of participants from the city of Baltimore, Md., the study could help researchers eventually develop strategies to prevent CKD in vulnerable populations.

9 Jun 2010

Pharnext closes €4.8-million Series A funding round

Pharnext SAS, a biopharmaceutical company specializing in the development of innovative treatments based on Pleotherapy™ for severe neurological diseases, today announced that it had closed a €4.8-million Series A round of funding on June 3rd (corresponding to a company valuation of €45 million).

9 Jun 2010

Scientists combine two agents to treat patients with multiple myeloma

Scientists from the Barbara Ann Karmanos Cancer Institute in Detroit presented data showing that by combining two treatment agents in the care of multiple myeloma patients, doctors can use higher dosages of chemotherapy before autologous stem cell transplant while alleviating painful and debilitating side effects like severe oral mucositis (mouth ulcers).

8 Jun 2010

Chemotherapy drug sunitinib promising for HIV-positive cancer patients

Preliminary findings from a unique study with sunitinib suggest that it might be possible to tweak the dosage of chemotherapy drugs used to treat HIV-positive cancer patients to achieve therapeutic benefit. Given the type of drug cocktail patients use to treat their HIV, much more or considerably less chemotherapy may be warranted, say the researchers, part of the NCI-supported AIDS Malignancy Consortium (AMC). The trial design is being presented at the 2010 annual meeting of the American Society of Clinical Oncology (ASCO).

8 Jun 2010

U.S. Renal Care acquires Dialysis Corporation of America for $110.25M

U.S. Renal Care, Inc., a leading privately-held provider of outpatient dialysis services, today announced that it has completed its $110.25 million acquisition of Dialysis Corporation of America, Inc., a leading provider of outpatient kidney dialysis services. With this acquisition, USRC will provide dialysis services to approximately 5,500 patients and operate 84 dialysis centers, home and specialty hospital dialysis programs and facilities in nine states: Arkansas, Georgia, Maryland, New Jersey, Ohio, Pennsylvania, South Carolina, Texas, and Virginia.

8 Jun 2010

Novartis' Afinitor decreases size of SEGAs associated with tuberous sclerosis

Novartis Pharmaceuticals Corporation announced today that results from a Phase II study show Afinitor® (everolimus) tablets is the first medication in a clinical trial to decrease the size of subependymal giant cell astrocytomas (SEGAs), benign brain tumors associated with tuberous sclerosis (TS). In this study of 28 patients presented today at the 46th American Society of Clinical Oncology (ASCO) annual meeting in Chicago, 75% of patients experienced a reduction of 30% or greater in the size of their brain tumors from baseline to six months (p<0.001).

7 Jun 2010

Addition of sorafenib to chemotherapy regimen not effective against advanced melanoma: Study

The combination of two different chemotherapies and a previously approved treatment for kidney and liver cancers is not effective against advanced melanoma, according to results disclosed in an oral presentation today at the 46th annual meeting of the American Society of Clinical Oncology in Chicago.

7 Jun 2010

Researcher calls stroke specialists to further knowledge and understanding of stroke

To cope with the projected growth in the incidence of strokes in Canada, the public may need to take on roles traditionally performed by healthcare specialists, according to a leading Canadian stroke researcher.

7 Jun 2010

NewYork-Presbyterian Hospital recognized as leader in all 10 clinical specialties

NewYork-Presbyterian Hospital is the only tri-state-area hospital listed on the 2010 U.S.News & World Report "America's Best Children's Hospitals" "Honor Roll" and one of only eight children's hospitals in the nation to be ranked in all 10 clinical specialties. NewYork-Presbyterian provides children's health services at two major centers: NewYork-Presbyterian/Morgan Stanley Children's Hospital and the Phyllis and David Komansky Center for Children's Health.

5 Jun 2010

Millennium announces data on VELCADE in treatment of patients with amyloidosis

Millennium: The Takeda Oncology Company today announced data examining the use of VELCADE in the treatment of patients with relapsed or refractory light chain (AL) amyloidosis. Amyloidosis is a rare condition in which excessive proteins build up in organs or tissues, such as the heart, kidney or liver. These data were presented at the Annual Meeting of the American Society of Clinical Oncology (ASCO) held in Chicago, Illinois, June 4-8, 2010.

5 Jun 2010

Montefiore-Einstein announces Abdominal Organ Transplant Symposium on June 10, 2010

The Montefiore-Einstein Abdominal Organ Transplantation Service will hold an Abdominal Organ Transplant Symposium on Thursday, June 10, 2010 from 7:30 am - 4:30 pm at the Moses Division of Montefiore Medical Center on Gun Hill Road in the Bronx, NY.

4 Jun 2010

DaVita receives subpoena from Department of Health and Human Services OIG

DaVita Inc., a leading provider of kidney care services for those diagnosed with chronic kidney disease (CKD), announced today that on May 28, 2010, it received a subpoena from the Dallas office of the Department of Health and Human Services, Office of Inspector General (OIG). The subpoena relates to a civil investigation that was previously disclosed by the company during its earnings call on April 27, 2010, and in its quarterly report on form 10-Q for the period ended March 31, 2010.

4 Jun 2010

Kidney dialysis patients unprepared for disasters: Study

Immediately after Hurricane Katrina in August 2005, the survival of more than 5,800 Gulf Coast kidney dialysis patients was threatened as the storm forced closure of 94 dialysis units. Within a month 148 of these patients had died.

4 Jun 2010

Growth hormone treatment promotes growth in infants with CRF: Study

Infants with chronic renal failure grow slowly, a problem that usually improves with aggressive nutritional therapy. When it doesn't, growth hormone is a safe and effective treatment to promote growth, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

4 Jun 2010

Hiru, MindUp BioResearch comment on recent research findings in cancer treatments

Hiru Corporation and its European subsidiary MindUp BioResearch comment on the recent research findings in the field of cancer treatments for multi-drug resistant non-small cell lung cancer.

4 Jun 2010

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

A detailed analysis of the epigenetics - factors controlling when and in what tissues genes are expressed - of Wilms tumor reveals striking similarities to stem cells normally found in fetal kidneys. These findings by Massachusetts General Hospital Cancer Center researchers have revealed new cellular pathways that are critical for Wilms tumor development and may also apply to other pediatric cancers.

4 Jun 2010

Grassroots awareness and education programs increase minority organ and tissue donations: Study

Minority organ donations have more than doubled since the institution of grassroots awareness and education programs, according to a new retrospective study published in the May issue of the Journal of the American College of Surgeons. In 2010, the percentage of minority donors is expected to reach 35 percent, up from approximately 15 percent in 1990.

3 Jun 2010

Kidney News and Research

TF2 bispecific antibody pretargeted therapy prolongs survival in animal model of human colonic cancer

University of Missouri researchers to investigate cadmium's potential for causing endometrial cancer

Researchers receive funding to study care processes in patients beginning dialysis

Low-income African-Americans have higher risk of CKD: Research

Pharnext closes €4.8-million Series A funding round

Scientists combine two agents to treat patients with multiple myeloma

Chemotherapy drug sunitinib promising for HIV-positive cancer patients

U.S. Renal Care acquires Dialysis Corporation of America for $110.25M

Novartis' Afinitor decreases size of SEGAs associated with tuberous sclerosis

Addition of sorafenib to chemotherapy regimen not effective against advanced melanoma: Study

Researcher calls stroke specialists to further knowledge and understanding of stroke

NewYork-Presbyterian Hospital recognized as leader in all 10 clinical specialties

Millennium announces data on VELCADE in treatment of patients with amyloidosis

Montefiore-Einstein announces Abdominal Organ Transplant Symposium on June 10, 2010

DaVita receives subpoena from Department of Health and Human Services OIG

Kidney dialysis patients unprepared for disasters: Study

Growth hormone treatment promotes growth in infants with CRF: Study

Hiru, MindUp BioResearch comment on recent research findings in cancer treatments

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

Grassroots awareness and education programs increase minority organ and tissue donations: Study

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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