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New research shows schizophrenia comprises 8 genetically distinct disorders

New research shows that schizophrenia isn't a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms. The finding could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness.

16 Sep 2014

Collaborative study takes important step toward finding targeted treatments for bladder cancer

The story of cancer care seems so simple: find the mutated gene that causes cancer and turn it off or fix it. But rarely does a single gene cause cancer. More often, many genes are altered together to drive the disease. So the challenge becomes sorting out which altered genes are the most to blame in which cancers.

16 Sep 2014

Patients with particular genetic variation more prone to drug-induced pancreatitis

Doctors have discovered that patients with a particular genetic variation are four times more likely to develop pancreatitis if they are prescribed a widely used group of drugs.

16 Sep 2014

Six research institutions awarded NIH grants to create database of human cellular responses

Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses, the Library of Integrated Network-based Cellular Signatures.

15 Sep 2014

BGI-VPC Joint Research Laboratory to apply genome research to develop new cancer therapies

BGI, the world’s largest genomics organization, based in China, and The Vancouver Prostate Centre, a global leader in translational research in cancer, today announced the establishment of the BGI-VPC Joint Research Laboratory, a sequencing and translational research facility, to jointly discover and advance basic and translational programs in oncology, including personalized oncology.

15 Sep 2014

Human stem cells can be reset to their native undifferentiated state

Scientists at the Babraham Institute, in collaboration with colleagues at the Cambridge Stem Cell Institute and the European Bioinformatics Institute, have made a breakthrough in stem cell research. Their paper, published today in Cell, describes how human stem cells can be reverted back to non-specialised cells.

11 Sep 2014

Research gives scientists new insight into evolution of gibbon genome

A team led by an Oregon Health & Science University researcher has sequenced and annotated the genome of the only ape whose DNA had yet to be sequenced - the gibbon, an endangered small ape that inhabits the tropical forests of Southeast Asia.

11 Sep 2014

Scientists crack genetic code of liver fluke parasite

Singapore-An international team of scientists from Singapore, Thailand, China and Australia has cracked the genetic code of the liver fluke parasite, Opisthorchis viverrini, using a unique DNA analysis technique developed at A*STAR's Genome Institute of Singapore (GIS).

11 Sep 2014

Dell, Terascala and TGen to install genomic data management solution at NCI

Dell, Terascala and the Translational Genomics Research Institute are installing state-of-the-art computing and programing specialized for human genome investigations at the National Cancer Institute.

10 Sep 2014

Researchers identify non-protein-coding RNA whose expression linked to ovarian cancer

Over the years researchers have made tremendous strides in the understanding and treatment of cancer by searching genomes for links between genetic alterations and disease.

10 Sep 2014

Novel virus could be source of severe respiratory disease in ball pythons

Researchers have identified a novel virus that could be the source of a severe, sometimes fatal respiratory disease that has been observed in captive ball pythons since the 1990s. The work is published this week in mBio-, the online open-access journal of the American Society for Microbiology.

9 Sep 2014

NanoTracker™ Optical Tweezers system used at Leiden University to study the organisation of genomic DNA

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the use of the NanoTracker™ Optical Tweezers system in the Laboratory of Molecular Genetics in the Leiden Institute of Chemistry at Leiden University.

9 Sep 2014

Protein RBM4 drastically decreases multiple forms of human cancer

Researchers from the UNC School of Medicine have discovered that the protein RBM4, a molecule crucial to the process of gene splicing, is drastically decreased in multiple forms of human cancer, including lung and breast cancers.

9 Sep 2014

Combination miRNA therapy offers promising therapeutic avenue for non-small-cell lung cancer

Micro RNAs (miRNA) have recently emerged as key therapeutic agents against cancers and are actively being evaluated in pre-clinical models of various cancers as well as in human clinical trials.

8 Sep 2014

DNA regions that contained telomeres generate RNAs

RNA is one of the most primitive molecules associated with life that has awakened most interest over the last decade; a sister molecule to cellular DNA from which it originates via a process called transcription.

4 Sep 2014

Distinct features of COPD–asthma overlap syndrome identified

US researchers have shown that patients with both chronic obstructive pulmonary disease and asthma have more exacerbations, less emphysema and more airway disease than patients with COPD alone.

3 Sep 2014

Two fully automated molecular testing systems for blood and plasma donor screening launched by Roche

Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the commercial availability of the cobas 6800/8800 Systems, two integrated and fully automated molecular testing systems for blood and plasma donor screening, in markets accepting the CE mark. The cobas 6800/8800 Systems offer the fastest time to results with the highest throughput available, along with the longest walk-away time, enabling laboratory staff to drive increased workflow efficiencies, while adapting to their ever-changing testing demands.

From Roche Sequencing and Life Science 2 Sep 2014

Changes in ADNP gene may provide further insight into causes of autism

A new study from Bradley Hospital has identified a genetic change in a recently identified autism-associated gene, which may provide further insight into the causes of autism. The study, now published online in the Journal of Medical Genetics, presents findings that likely represent a definitive clinical marker for some patients' developmental disabilities.

29 Aug 2014

TGen to lead first-in-patient clinical trial studies to test novel drugs for glioblastoma

SIn 2012, The Ben & Catherine Ivy Foundation awarded $10 million in grants for two groundbreaking brain cancer research projects at the Translational Genomics Research Institute. One of those projects has officially received the final regulatory approval from University of California, San Francisco, which means patient enrollment for the trial can begin.

29 Aug 2014

Researchers report that predominant CA-MRSA strain migrated from sub-Saharan Africa

The predominant strain of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infecting people in Europe, the Middle East and northern Africa derived from a single sub-Saharan ancestor, a team of international researchers reported this week in mBio-, the online open-access journal of the American Society for Microbiology.

26 Aug 2014

Genome News and Research

New research shows schizophrenia comprises 8 genetically distinct disorders

Collaborative study takes important step toward finding targeted treatments for bladder cancer

Patients with particular genetic variation more prone to drug-induced pancreatitis

Six research institutions awarded NIH grants to create database of human cellular responses

BGI-VPC Joint Research Laboratory to apply genome research to develop new cancer therapies

Human stem cells can be reset to their native undifferentiated state

Research gives scientists new insight into evolution of gibbon genome

Scientists crack genetic code of liver fluke parasite

Dell, Terascala and TGen to install genomic data management solution at NCI

Researchers identify non-protein-coding RNA whose expression linked to ovarian cancer

Novel virus could be source of severe respiratory disease in ball pythons

NanoTracker™ Optical Tweezers system used at Leiden University to study the organisation of genomic DNA

Protein RBM4 drastically decreases multiple forms of human cancer

Combination miRNA therapy offers promising therapeutic avenue for non-small-cell lung cancer

DNA regions that contained telomeres generate RNAs

Distinct features of COPD–asthma overlap syndrome identified

Two fully automated molecular testing systems for blood and plasma donor screening launched by Roche

Changes in ADNP gene may provide further insight into causes of autism

TGen to lead first-in-patient clinical trial studies to test novel drugs for glioblastoma

Researchers report that predominant CA-MRSA strain migrated from sub-Saharan Africa

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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