Infectious Diseases News and Research

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New Jefferson Hepatitis C Center

Thomas Jefferson University Hospital recently opened its new Jefferson Hepatitis C Center, one of only a few comprehensive, multidisciplinary centers dedicated to the study of hepatitis C virus and hepatic disease in the Pennsylvania, New Jersey and Delaware tri-state area.

14 May 2012

JHSPH wins GCE grant for global health and development research project

The Johns Hopkins Bloomberg School of Public Health announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation. Alain Labrique, PhD, director of the Johns Hopkins University Global mHealth Initiative, will pursue an innovative global health and development research project, titled "mTIKKA - Harnessing a Mobile - Cloud System to Achieve Universal Vaccination."

14 May 2012

New insights into how body's innate immunity is triggered to create effective immune response

Singapore scientists from Bioprocessing Technology Institute (BTI) under the Agency of Science, Technology and Research (A*STAR) have for the first time, identified the molecular 'switch' that directly triggers the body's first line of defence against pathogens, more accurately known as the body's "innate immunity".

11 May 2012

Bacteria in digestive tracts compete against invading bacteria

From tiny villages in developing nations to suburban kitchens in the United States, dangerous strains of E. coli bacteria sicken millions of people each year - and kill untold numbers of children.

11 May 2012

Hospital midwife inadvertently spreads whooping cough to up to 170 people

A Middlemore Hospital midwife could have infected up to 170 people with whooping cough. If passed onto babies or women in the last three months of pregnancy, the disease can lead to severe illness or even death. Whooping cough is a highly infectious disease caused by bacteria which is easily spread through coughing and sneezing, much like the common cold. Also known as pertussis, it is distinguishable by a “whooping” sound at the end of coughing attacks.

10 May 2012

International community, U.S. should increase resources, mandate for fighting NCDs in developing world

In this Foreign Affairs essay, Thomas Bollyky, a senior fellow for global health, economics and development at the Council on Foreign Relations, examines the increase of non-communicable diseases (NCDs) in the developing world.

10 May 2012

Researchers use clever screening methods to speed vaccine production

Infectious diseases-both old and new-continue to exact a devastating toll, causing some 13 million fatalities per year around the world. Vaccines remain the best line of defense against deadly pathogens and now Kathryn Sykes and Stephen Johnston, researchers at Arizona State University's Biodesign Institute, along with co-author Michael McGuire from the University of Texas Southwestern Medical Center are using clever functional screening methods to attempt to speed new vaccines into production that are both safer and more potent.

10 May 2012

IDRI, Aeras partner to develop new TB vaccine candidate

Aeras and the Infectious Disease Research Institute (IDRI) announce today a new agreement to conduct joint development activities with respect to IDRI's novel tuberculosis vaccine candidate. This collaboration reflects the missions of the two non-profit product development partnerships to use cutting-edge science to develop products that address critical diseases of underserved populations around the world, including tuberculosis.

10 May 2012

Inovio first quarter total revenue decreases to $1.7 million

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended March 31, 2012.

10 May 2012

One in six cancer cases worldwide related to preventable or curable infections

New research shows that one in six cancers - amounting to two million a year globally - are caused by largely treatable or preventable infections.

9 May 2012

Reusable grocery bag can play a role in spreading norovirus infection

Oregon investigators recently mapped the trail of an outbreak of a nasty stomach bug among participants in a girls' soccer tournament to a reusable open top grocery bag stored in a hotel bathroom. Their findings, which illustrate the role that inanimate objects can play in spreading norovirus infection, appear in The Journal of Infectious Diseases.

9 May 2012

Advaxis commences enrollment in ADXS-HPV Phase 1/2 study for head and neck cancer

Advaxis, Inc.,, a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that two patients have been enrolled into REALISTIC, a Phase 1/2 study being sponsored by Cancer Research UK (CRUK) to investigate the use of ADXS-HPV for the treatment of HPV positive head and neck cancer. HPV is associated with 40-70% of head and neck cancers.

8 May 2012

Certain males at higher risk of infection after receiving experimental HIV vaccine

A long-term follow-up analysis of participants in the Step Study, an international HIV-vaccine trial, has confirmed that certain subgroups of male study participants were at higher risk of becoming infected after receiving the experimental vaccine compared to those who received a placebo.

8 May 2012

Metformin blocks uveitis in laboratory rats

University of Texas Medical Branch at Galveston researchers have discovered that a drug already prescribed to millions of people with diabetes could also have another important use: treating one of the world's leading causes of blindness.

8 May 2012

Cholera strain in Haiti evolving, CDC reports

"The cholera strain in Haiti is evolving, researchers reported Thursday, a sign that it may be taking deeper root in the nation less than two years after it appeared and killed thousands of people," the Associated Press/USA Today reports.

8 May 2012

VOA News examines South Africa's rural public health sector

VOA News features a five-part series on South Africa's rural public health sector, which the news service writes is "plagued by a high burden of infectious diseases, severe doctor and nurse shortages, lack of medicines and essential medical equipment and incompetent management," resulting in high patient death rates.

8 May 2012

Meningitis B vaccine on the horizon

Meningitis B is particularly dangerous for children, leading to 120 deaths in the UK every year. There are around 1,200 new cases of meningitis B every year. Around 1 in 10 victims die and another 15 per cent are left with permanent disabilities - often limbs have to be amputated due to blood poisoning. The infection causes inflammation of the membranes surrounding the spinal cord and brain. Symptoms include a severe headache, vomiting, a rash, sensitivity to light and a stiff neck.

8 May 2012

NovaDigm reports positive data from Phase 1 NDV-3 vaccine program

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced the presentation of positive data for its NDV-3 vaccine program in a second Phase 1 study.

7 May 2012

NFID to host 15th Annual Conference on Vaccine Research from May 7–9

The National Foundation for Infectious Diseases will host the 15th Annual Conference on Vaccine Research, May 7–9, 2012, at the Hyatt Regency Inner Harbor in Baltimore, MD.

5 May 2012

One of the controversial avian flu studies published in full finally

After endless debates and controversies on whether two studies that demonstrated how bird flu, also known as avian H5N1 influenza, or avian flu, should be published, one of them has appeared in the latest issue of the journal Nature in its entirety. The two studies aimed for publication in journals Nature and Science show how the bird flu virus could become transmissible from mammal-to-mammal; as humans are mammals, the same would apply to humans.

4 May 2012