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Study finds a host of new clues on gene-environment interactions in Crohn's disease

A new study finds a wide range of epigenetic changes-alterations in DNA across the genome that may be related to key environmental exposures-in children with Crohn's disease (CD), reports Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America.

23 Aug 2014

Research: Seals and sea lions may spread tuberculosis to humans

Tuberculosis is one of the most persistent and deadliest infectious diseases in the world, killing one to two million people each year.

21 Aug 2014

Deep sequencing technique opens up new possibilities for finding genetic causes for brain disorder

Not every cell in the body is the same genetically, and disease-causing mutations don't necessarily affect every cell—making these mutations easy to miss even with next-generation genomic sequencing.

21 Aug 2014

VCU receives federal grant totaling $6.9 million to study genetics of alcohol abuse

Virginia Commonwealth University has received a federal grant totaling $6.9 million to study the genetics of alcohol abuse and alcoholism - work that may lead to further advances in its treatment, control and prevention.

20 Aug 2014

Scientists identify biomarker strongly associated with aggressive breast cancer

Two Northwestern University scientists have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy. The biomarker, a protein called STAT3, provides a smart target for new therapeutics designed to treat this often deadly cancer.

20 Aug 2014

Viewpoints: Va. GOP's 'Medicaid charade'; Paul Ryan's health Rx for poverty; giving the sick unapproved drugs

Virginia lawmakers will convene in a special session next month to address the question of expanding Medicaid and, more broadly, the fact that hundreds of thousands of poor and disabled people in the state have no health insurance coverage. Democrats and some moderate Republicans have advanced a variety of ideas to tackle that problem. Conservative Republicans, who control the legislature in Richmond, have rejected those solutions while proposing no alternative. Does the GOP intend for the special session to be anything more than a charade at taxpayers' expense? (8/15).

19 Aug 2014

Researchers uncover role of epigenetic changes in Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease.

19 Aug 2014

Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

A new study led by researchers at Brigham and Women's Hospital (BWH) and Rush University Medical Center, reveals how early changes in brain DNA methylation are involved in Alzheimer's disease.

18 Aug 2014

Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD

With three billion letters in the human genome, it seems hard to believe that adding a DNA base here or removing a DNA base there could have much of an effect on our health.

18 Aug 2014

Researchers use new gene editing method to correct mutation that leads to DMD

UT Southwestern Medical Center researchers successfully used a new gene editing method to correct the mutation that leads to Duchenne muscular dystrophy (DMD) in a mouse model of the condition.

17 Aug 2014

Scientists create computer algorithm for cell and tissue engineering

In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a "roadmap" for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

16 Aug 2014

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Researchers from Boston University School of Medicine report that a tumor suppressor pathway, called the Hippo pathway, is responsible for sensing abnormal chromosome numbers in cells and triggering cell cycle arrest, thus preventing progression into cancer.

16 Aug 2014

Babies suffering from life-threatening bacterial infections could benefit from improved treatment

Babies suffering from life-threatening bacterial infections such as sepsis could benefit from improved treatment, thanks to a ground-breaking study.

14 Aug 2014

Researchers find that nanopores in material MoS2 could sequence DNA more accurately

Gene-based personalized medicine has many possibilities for diagnosis and targeted therapy, but one big bottleneck: the expensive and time-consuming DNA-sequencing process.

14 Aug 2014

Identifying epigenetic markers in cancer cells could improve patient treatment

Scientists have known for decades that cancer can be caused by genetic mutations, but more recently they have discovered that chemical modifications of a gene can also contribute to cancer.

13 Aug 2014

23andMe, Pfizer partner to explore genetic factors associated with IBD

23andMe, the leading personal genetics company today announced an agreement with Pfizer Inc. in which the companies will aim to enroll 10,000 people with Inflammatory Bowel Disease (IBD) in a research initiative designed to explore the genetic factors associated with the onset, progression, severity and response to treatments for IBD.

12 Aug 2014

Scientists aim to understand and treat painful bladder condition

Taking advantage of technology that can analyze tissue samples and measure the activity of thousands of genes at once, scientists at Wake Forest Baptist Medical Center are on a mission to better understand and treat interstitial cystitis (IC), a painful and difficult-to-diagnose bladder condition.

12 Aug 2014

Bacteria may depend more on gastrointestinal age than on environmental factors in babies

Scientists believe babies are born with digestive systems containing few or no bacteria. Their guts then quickly become colonized by microbes — good and bad — as they nurse or take bottles, receive medication and even as they are passed from one adoring relative to another.

12 Aug 2014

Researchers discover highly virulent, multidrug resistant form of pathogen in Ohio

A team of clinician researchers has discovered a highly virulent, multidrug resistant form of the pathogen, Pseudomonas aeruginosa, in patient samples in Ohio.

12 Aug 2014

New approach to knocking out parasite's genes

Plasmodium falciparum, the parasite that causes malaria, has proven notoriously resistant to scientists' efforts to study its genetics.

12 Aug 2014

Genome News and Research

Study finds a host of new clues on gene-environment interactions in Crohn's disease

Research: Seals and sea lions may spread tuberculosis to humans

Deep sequencing technique opens up new possibilities for finding genetic causes for brain disorder

VCU receives federal grant totaling $6.9 million to study genetics of alcohol abuse

Scientists identify biomarker strongly associated with aggressive breast cancer

Viewpoints: Va. GOP's 'Medicaid charade'; Paul Ryan's health Rx for poverty; giving the sick unapproved drugs

Researchers uncover role of epigenetic changes in Alzheimer's disease

Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD

Researchers use new gene editing method to correct mutation that leads to DMD

Scientists create computer algorithm for cell and tissue engineering

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Babies suffering from life-threatening bacterial infections could benefit from improved treatment

Researchers find that nanopores in material MoS2 could sequence DNA more accurately

Identifying epigenetic markers in cancer cells could improve patient treatment

23andMe, Pfizer partner to explore genetic factors associated with IBD

Scientists aim to understand and treat painful bladder condition

Bacteria may depend more on gastrointestinal age than on environmental factors in babies

Researchers discover highly virulent, multidrug resistant form of pathogen in Ohio

New approach to knocking out parasite's genes

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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