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How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

Researchers set gold standards for developing new painkillers based on medicinal effects of cannabis

Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set 'gold standards' for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.

4 Jan 2017

Chemical modification improves release and availability of insulin, research shows

Replacing a hydrogen atom by an iodine atom in insulin, the hormone retains its efficacy but is available more rapidly to the organism.

3 Jan 2017

Powerful version of anti-inflammatory molecule may help protect vision in diabetic retinopathy

A more powerful version of an anti-inflammatory molecule already circulating in our blood may help protect our vision in the face of diabetes.

3 Jan 2017

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease.

3 Jan 2017

TSRI researchers develop new approach to find how environmental estrogens impact public health

Breast cancer researchers from the Florida campus of The Scripps Research Institute have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer.

3 Jan 2017

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment--called environmental estrogens--can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer.

30 Dec 2016

Acute stress can lead to delayed, long-term psychological trauma

Mrs. M would never forget that day. She was walking along a busy road next to the vegetable market when two goons zipped past on a bike. One man's hand shot out and grabbed the chain around her neck.

30 Dec 2016

New molecular imaging technologies can make it easier to treat cancers, minimize side effects

New molecular imaging technologies can make it easier to diagnose, monitor, and treat cancers while potentially saving patients from undergoing therapies that are likely to be ineffective and playing a role in minimizing side effects, according to experts from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania.

30 Dec 2016

Two research studies on new molecules could potentially treat Alzheimer's disease

This year, results have been published of two significant research studies about molecules that could potentially treat Alzheimer's disease.

30 Dec 2016

Physical inactivity in obese mice linked to dopamine signaling defects

Starting a regular program at the gym is a common New Year's resolution, but it's one that most people are unable to stick with for very long.

30 Dec 2016

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the benefit of biomarker tests to support the decision for or against adjuvant systemic chemotherapy in certain breast cancer patients, that is, women with primary hormone receptor-positive, HER2-negative breast cancer and up to 3 affected lymph nodes.

30 Dec 2016

New evidence may explain how gut microorganisms affect human physiology

Researchers have found evidence that could shed new light on the complex community of trillions of microorganisms living in all our guts, and how they interact with our bodies.

30 Dec 2016

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity.

28 Dec 2016

FDA grants permission to assess safety of investigational drug for Alzheimer's disease in humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer's disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

28 Dec 2016

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress of emphysema, a common component of chronic obstructive pulmonary disease (COPD).

27 Dec 2016

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, has presented new prospective data demonstrating the strong impact of its 70-Gene Breast Cancer Recurrence assay, MammaPrint, and the corresponding 80-Gene Molecular Subtyping Assay BluePrint, in clinical decision-making for patients with early-stage breast cancer in Germany.

22 Dec 2016

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

New data presented at the 2016 San Antonio Breast Cancer Symposium (SABCS) demonstrate that analyzing tumor biology with the Oncotype DX test can identify patients unlikely to benefit from chemotherapy prior to breast cancer surgery (neoadjuvant setting) and guide treatment decisions without compromising outcomes.

22 Dec 2016

New research offers valuable insight for developing more effective drugs to treat IBD

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis.

22 Dec 2016

UNC scientists develop new tool to study G-protein signaling

Scientists from the UNC School of Medicine have developed a new tool for studying a key process in cells called G-protein signaling, which plays a central role in the normal functioning of cells and can go awry to cause severe disease, including cancers.

22 Dec 2016

Receptor News and Research

How does the brain control appetite?

Researchers set gold standards for developing new painkillers based on medicinal effects of cannabis

Chemical modification improves release and availability of insulin, research shows

Powerful version of anti-inflammatory molecule may help protect vision in diabetic retinopathy

Targeting Legumain could be promising strategy for treatment of cancer

TSRI researchers develop new approach to find how environmental estrogens impact public health

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Acute stress can lead to delayed, long-term psychological trauma

New molecular imaging technologies can make it easier to treat cancers, minimize side effects

Two research studies on new molecules could potentially treat Alzheimer's disease

Physical inactivity in obese mice linked to dopamine signaling defects

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

New evidence may explain how gut microorganisms affect human physiology

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

FDA grants permission to assess safety of investigational drug for Alzheimer's disease in humans

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

New research offers valuable insight for developing more effective drugs to treat IBD

UNC scientists develop new tool to study G-protein signaling

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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