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Scientists at Salk Institute develop novel platform to study kidney diseases

Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology.

19 Nov 2013

GM-CSF therapy does not improve treadmill walking time in patients with peripheral artery disease

Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte-macrophage colony stimulating factor (GM-CSF), an agent that functions as a white blood cell growth factor, would improve walking performance in patients with symptomatic peripheral artery disease (a form of vascular disease in which there is partial or total blockage of an artery, usually one leading to a leg or arm).

19 Nov 2013

Study confirms therapeutic potential of inhibiting Aurora-A in cancer treatment

Aurora-A is a protein involved in the cell division process that is highly expressed or synthesised in a large number of human cancers, especially in those associated with a bad prognosis. Several pharmaceutical companies have recently developed these protein inhibitors, although the therapeutic and physiological effects that blocking Aurora-A might have on adult tissues are still unknown.

19 Nov 2013

Layers of skin that form first line of defence in body's fight against infection reveal secret

The layers of skin that form the first line of defence in the body's fight against infection have revealed a unanticipated secret.

19 Nov 2013

Vismodegib drug does not offer added benefits for patients with BCC

The drug vismodegib (trade name: Erivedge) is approved for the treatment of patients with two forms of basal cell carcinoma: symptomatic metastatic BCC and locally advanced BCC inappropriate for surgery or radiotherapy.

19 Nov 2013

Medical image exchange: an interview with Willie Tillery, CEO of Accelarad

Accelarad’s team first recognized the need for the virtualization of radiology more than 10 years ago. Over the past six years, the industry has readily adopted cloud-based medical image exchanges, as evidenced by the thousands of physicians who share nearly half a billion images via Accelarad each year.

18 Nov 2013

New hope for patients whose melanoma has metastasised to the brain

New data show that in patients whose melanoma (BRAF V600 mutation-positive) has spread (metastasised) to the brain, Zelboraf (vemurafenib) extends life expectancy by over six months compared to chemotherapy.1 These results are welcome news for patients suffering from metastatic melanoma, as up to half of these patients are diagnosed with brain metastases with many given less than six months to live.1

18 Nov 2013

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Findings by scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna reveal a surprising role for histone deacetylase 1 (HDAC1) - a member of a family of chromatin modifying proteins - in the development of skin tumors.

18 Nov 2013

Researchers generate three-dimensional kidney structures from human stem cells

18 Nov 2013

Researchers explain new function of 2 key molecules involved in tumor progression

Researchers from IMIM (Hospital del Mar Medical Research Institute) lead by Dr. Sandra Peir- have described a new function for two key molecules involved in tumor progression.

16 Nov 2013

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Skin provides a first line of defense against viruses, bacteria and parasites that might otherwise make people ill. When an injury breaks that barrier, a systematic chain of molecular signaling launches to close the wound and re-establish the skin's layer of protection.

16 Nov 2013

Bleach solution could provide new way to treat skin damage

Processes that age and damage skin are impeded by dilute bleach solution, according to a new study by researchers at the Stanford University School of Medicine.

16 Nov 2013

New technique helps fight deadly pancreatic cancer using 2 types of nanoparticles

Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a new technique for fighting deadly and hard-to-treat pancreatic cancer that uses two different types of nanoparticles, the first type clearing a path into tumor cells for the second, which delivers chemotherapy drugs.

16 Nov 2013

Novel combination anti-psoriasis therapy targets genetic abnormalities in deeper layers of the skin

A novel combination anti-psoriasis therapy has potential for superior and longer-lasting therapeutic effects than current topical treatments by targeting genetic abnormalities in deeper layers of the skin. This research is being presented at the 2013 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in San Antonio, Nov. 10-14.

15 Nov 2013

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research from postdoctoral fellow Lick Lai in the lab of USC scientist Andy McMahon published in Proceedings of the National Academy of Sciences (PNAS) sheds light on how this important protein keeps people organized on a basic level by promoting orderly skeletal growth and preventing skeletal tumors.

15 Nov 2013

Scientists discover new drug mechanism to reduce risk of infections

Scientists at A*STAR's Singapore Immunology Network (SIgN) have discovered the exact mode of action by plerixafor, a drug commonly prescribed to stimulate immune responses in patients suffering from neutropenia, which causes them to become prone to oral, skin, genital infections and in worst cases, a fatal whole-body infection.

15 Nov 2013

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Signum Dermalogix, Inc. announced that the National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the company a Small Business Innovation Research Phase II grant totaling $1.6 million for the development of a topical drug candidate for atopic dermatitis.

15 Nov 2013

Parkinson’s biomarker could be only skin deep

Deposits of α-synuclein in cutaneous nerves could represent a noninvasive biomarker for Parkinson’s disease, say researchers.

14 Nov 2013

Nutranomics to distribute Nutriband transdermal delivery system in North America

Nutranomics, Inc. is pleased to announce that the Company has acquired the exclusive North American sales and distribution rights to the Nutriband delivery system, an innovative and commercialized health supplement transdermal patch system currently available in Europe.

14 Nov 2013

Researchers generate most complete genome sequences from single cells and individual neurons

Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.

14 Nov 2013

Skin News and Research

Scientists at Salk Institute develop novel platform to study kidney diseases

GM-CSF therapy does not improve treadmill walking time in patients with peripheral artery disease

Study confirms therapeutic potential of inhibiting Aurora-A in cancer treatment

Layers of skin that form first line of defence in body's fight against infection reveal secret

Vismodegib drug does not offer added benefits for patients with BCC

Medical image exchange: an interview with Willie Tillery, CEO of Accelarad

New hope for patients whose melanoma has metastasised to the brain

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Researchers generate three-dimensional kidney structures from human stem cells

Researchers explain new function of 2 key molecules involved in tumor progression

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Bleach solution could provide new way to treat skin damage

New technique helps fight deadly pancreatic cancer using 2 types of nanoparticles

Novel combination anti-psoriasis therapy targets genetic abnormalities in deeper layers of the skin

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Scientists discover new drug mechanism to reduce risk of infections

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Parkinson’s biomarker could be only skin deep

Nutranomics to distribute Nutriband transdermal delivery system in North America

Researchers generate most complete genome sequences from single cells and individual neurons

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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