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Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy.

10 Nov 2021

Stenoparib effectively inhibits SARS-CoV-2 variants in vitro

A new study assesses the antiviral activity of stenoparib against four SARS-CoV-2 strains.

10 Nov 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

Retinoid therapy improves vision in mice with Usher syndrome

Using data generated from patients and mice with genetic mutation for the disorder Usher syndrome, researchers from the University of Maryland School of Medicine, the National Institutes of Health's National Eye Institute, and National Institute on Deafness and Other Communication Disorders, documented the natural history of vision impairment in patients and identified the cell mechanism behind progressive vision loss.

9 Nov 2021

Proton therapy used for the first time in Switzerland to treat lung cancer

Today a 60-year-old patient suffering from lung cancer received proton beam therapy, a medical procedure where positively charged particles are precisely targeted at the tumor. This is the first time this type of radiotherapy has been used for lung cancer treatment in Switzerland.

9 Nov 2021

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

9 Nov 2021

Radiation therapy puts childhood cancer survivors at higher risk of cardiometabolic disease

Decades after battling childhood cancer, survivors often face a new challenge: cardiometabolic disease. A spectrum of conditions that includes coronary heart disease and diabetes, cardiometabolic disease typically impacts people who are obese, elderly, or insulin resistant.

9 Nov 2021

Innovative imaging technology can measure temperature in 2D

A new imaging technique, developed by the teams of Professors Jinyang Liang and Fiorenzo Vetrone at the Institut national de la recherche scientifique, can measure temperature in 2D, without contact, and in just a snap.

9 Nov 2021

Researchers develop model for early prediction of cancer patients' response to immunotherapy

Researchers have developed a model that could predict early on in treatment whether cancer patients will respond to immunotherapy, according to a report published today in eLife.

9 Nov 2021

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Despite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation (ACR/NPF) in 2018, there is limited data regarding medication use in real-world clinical practice and patient medication preferences for the treatment of psoriatic arthritis (PsA).

9 Nov 2021

Researchers identify safety concerns with neuroblastoma candidate drug

St. Jude Children's Research Hospital scientists looking for drugs to improve survival of children with high-risk neuroblastoma found a promising candidate in CX-5461.

9 Nov 2021

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Cancer patients who are ineligible for clinical trials receive immune checkpoint inhibitors (ICI) at greater rates than patients who are trial eligible despite no survival benefit, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

9 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.

9 Nov 2021

Clinic-based review board helps reduce opioid prescribing

An internal medicine clinic at Oregon Health & Science University has sharply reduced the amount of opioids prescribed though innovative use of a review board comprising a team of health care professionals from various disciplines to ensure patients' needs are being met.

9 Nov 2021

Exercise can alleviate symptoms of anxiety, study shows

Both moderate and strenuous exercise alleviate symptoms of anxiety, even when the disorder is chronic, a study led by researchers at the University of Gothenburg shows.

9 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

COVID-19 drug candidate with wide-ranging antiviral activity

A new study investigated the antiviral activity and mechanism of action of Brilacidin against multiple human coronaviruses.

9 Nov 2021

As overdose deaths soar, DEA-wary pharmacies shy from dispensing addiction medication

When Martin Njoku saw opioid addiction devastate his West Virginia community, he felt compelled to help. This was the place he'd called home for three decades, where he'd raised his two girls and turned his dream of owning a pharmacy into reality.

9 Nov 2021

Therapy News and Research

Inhibiting epigenetic modification could be key to reducing cancer metastasis

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Stenoparib effectively inhibits SARS-CoV-2 variants in vitro

Current understanding of the link between COVID-19 and cardiovascular disease

Retinoid therapy improves vision in mice with Usher syndrome

Proton therapy used for the first time in Switzerland to treat lung cancer

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

Radiation therapy puts childhood cancer survivors at higher risk of cardiometabolic disease

Innovative imaging technology can measure temperature in 2D

Researchers develop model for early prediction of cancer patients' response to immunotherapy

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Researchers identify safety concerns with neuroblastoma candidate drug

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Targeting Shp2 in oncological treatments appears to worsen the disease

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Clinic-based review board helps reduce opioid prescribing

Exercise can alleviate symptoms of anxiety, study shows

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

COVID-19 drug candidate with wide-ranging antiviral activity

As overdose deaths soar, DEA-wary pharmacies shy from dispensing addiction medication

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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