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Study: Gene editing may correct genetic mutation responsible for Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a rare but devastating genetic disorder that causes muscle loss and physical impairments.

18 Sep 2019

Researchers identify an unexpected genetic plasticity in bat-borne influenza viruses

Bat-borne influenza viruses enter host cells by utilizing surface exposed MHC-II molecules of various species, including humans.

18 Sep 2019

Mutant live attenuated Ebola virus elicits protective immunity in monkeys

Inoculation with an Ebola virus that has mutations in a protein called VP35 does not cause disease and elicits protection in monkeys, researchers show September 17 in the journal Cell Reports.

17 Sep 2019

Exercise during pregnancy shown to restore metabolic health

A new study has shown that exercise can restore key tissues and reduce the risk of metabolic disorders such as type 2 diabetes.

2 Sep 2019

DNA vaccine for tick-borne disease ‘SFTS’ confers protection against lethal infection in ferrets

A KAIST research team reported the development of a DNA vaccine for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) which completely protects against lethal infection in ferrets.

29 Aug 2019

Study reveals link between popular pain medication and greater risk of hypoglycemia

Since its approval in 1995, the opioid tramadol (marketed as ConZip and Ultram) has become a widely prescribed remedy for osteoarthritis and other painful indications, in part because it presents a lesser risk for some side effects and has a lower abuse potential when compared to other opioids.

28 Aug 2019

Scientists discover potential novel target for treating deadly brain cancer

Scientists at USC and UC San Diego have discovered a potential novel target for treating glioblastoma, the deadly brain cancer that took the life of Sen. John McCain and kills 15,000 Americans a year.

28 Aug 2019

Study shows microRNA can protect the heart from reperfusion injury

Heart muscle can continue to die even after restoring blood following a heart attack, and scientists have new evidence that one way to help it live is by boosting levels of a tiny RNA that helped the heart form.

27 Aug 2019

Early detection method for pinpointing molecular signatures of Lyme disease

When researchers examined the mitochondrial DNA of Ötzi, a man entombed in ice high in the Tyrolean Alps some 5,300 years ago, they made a startling discovery.

26 Aug 2019

Investigating organ crosstalk leads to a better understanding of sepsis

Sepsis, a complex systemic response to infection leading to organ failure, is generally studied at the level of individual organs; this research has hinted at altered metabolic changes.

20 Aug 2019

Study uncovers potential new treatment approach for lung cancer

Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway.

19 Aug 2019

Loss of cells in the brain found to be associated with stuttering

Researchers believe that stuttering - a potentially lifelong and debilitating speech disorder - stems from problems with the circuits in the brain that control speech, but precisely how and where these problems occur is unknown.

19 Aug 2019

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Physicians have long suspected that red blood cell transfusions given to premature infants with anemia may put them in danger of developing necrotizing enterocolitis, or NEC, a potentially lethal inflammatory disease of the intestines.

From Johns Hopkins Medicine 13 Aug 2019

Researchers find new target for disease of the heart's smallest blood vessels

When we race walk, for example, part of our healthy heart muscle may want a little more blood and oxygen, so our tiniest blood vessels send a message upstream to the larger vessels to send more.

12 Aug 2019

Scientists identify hereditary pancreatic cancer risk mutation

Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers.

12 Aug 2019

Novel dual approach can be a promising way to enhance cardiac repair

As a medical emergency caused by severe cardiovascular diseases, myocardial infarction (MI) can inflict permanent and life-threatening damage to the heart.

12 Aug 2019

New technology can help interpret inaudible calls from laboratory mice

Technology that can help interpret inaudible calls from laboratory mice has been developed in a bid to improve research.

9 Aug 2019

Whole body vibration adjusts the microbiome and immune cells to deter inflammation in diabetes

In the face of diabetes, a common condition in which glucose and levels of destructive inflammation soar, whole body vibration appears to improve how well our body uses glucose as an energy source and adjust our microbiome and immune cells to deter inflammation, investigators report.

5 Aug 2019

Discovery of unusual HBV in shrews offers new opportunity to better understand the disease

The discovery of an unusual hepatitis B virus from shrews offers new opportunities of better understanding the chronic progression of the disease. International research teams were able to demonstrate that an important protein which is essential for the development of a chronic course of infection is not present in this virus.

3 Aug 2019

Asthma drug can inhibit changes in early stages of diabetic retinopathy

In a study published July 26 online in the journal Diabetes, physician-researchers from University Hospitals Rainbow Babies and Children's Hospital and Case Western Reserve University School of Medicine found that the asthma medication montelukast (brand name Singulair) can inhibit early changes in diabetic retinopathy, the eye disease which develops due to diabetes, in a mouse model of type 1 diabetes.

29 Jul 2019