Central Nervous System News and Research

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NIH awards first part of $30 million grant to USC team for stroke project

When administered soon after the onset of acute ischemic stroke, current approved treatments for the condition can dramatically improve patient outcomes.

24 May 2022

Gabapentin treatment may enhance recovery of movement after a stroke

The drug gabapentin, currently prescribed to control seizures and reduce nerve pain, may enhance recovery of movement after a stroke by helping neurons on the undamaged side of the brain take up the signaling work of lost cells, new research in mice suggests.

23 May 2022

Researchers analyze the development and genetic profile of brain's immune cells

Thanks to over a century of modern neuroscience, we have made significant strides in our understanding of the brain. Nonetheless, we have only just begun to scratch the surface of how this amazingly complex organ works.

20 May 2022

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

James Bibb, Ph.D., and colleagues have described a novel preclinical drug that could have the potential to combat depression, brain injury and diseases that impair cognition. The drug, which notably is brain-permeable, acts to inhibit the kinase enzyme Cdk5.

20 May 2022

Study explores neurologic complications in pediatric COVID-19 cases

Researchers evaluated neurologic complications in pediatric cases of COVID-19.

18 May 2022

Acoustic holograms enable efficient, selective opening of the blood brain barrier

The holograms designed by the team of researchers from UPV and CSIC allow the opening of the blood brain barrier selectively, efficiently and in a highly focused manner, facilitating the administration of therapeutic drugs to treat pathologies that affect the central nervous system.

17 May 2022

New drug inhibits growth of the most aggressive meningiomas

When a specific non-metastatic brain tumor — a meningioma — recurs after surgery and radiation treatment, a patient is normally out of options. No drugs are approved for these aggressive tumors, which occur in up to 20 percent of cases and can lead to patient disability or even death.

16 May 2022

Study assesses the effect of extreme heat on workforce health

Working outdoors during periods of extreme heat can cause discomfort, heat stress, or heat illnesses – all growing concerns for people who live and work in Southwestern cities like Las Vegas, where summer temperatures creep higher each year.

11 May 2022

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

An article published in the journal Molecular Psychiatry reveals the molecular mechanisms to explain how the YWHAZ gene –related to psychiatric and neurological disorders such as autism and schizophrenia– can alter the neurodevelopmental process.

10 May 2022

Telltale signs of concussions may be found in the gut, study suggests

A recently published study by Houston Methodist scientists suggests telltale signs of concussions might be found in the gut.

10 May 2022

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

A new study has focused on the microcirculatory factors associated with neurological complications of COVID-19.

10 May 2022

Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

A research led by Hong Kong University of Science and Technology has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.

9 May 2022

Insight into Neurological Diagnosis in Children

In this interview, we speak to Amy Brin, MSN, MA, PCNS-BC, CEO of the Child Neurology Foundation, about the current landscape of neurological diagnosis in children and the importance of helping patients and their families through the diagnosis and treatment process.

6 May 2022

Marine bioactive compounds against SARS-CoV-2

A new review paper published in the journal Environmental Science and Pollution Research aimed to determine the possibilities of using biologically active compounds derived from various chemical classes of marine organisms against SARS-CoV-2 infection at various stages of the life cycle of the virus.

6 May 2022

Prenatal exposure to SARS-CoV-2 raises risk of neurological disorders in infants

In a recent study published in the journal PLOS One, researchers investigated the early indicators of neurological dysfunctions, including the absence of fidgety movements, in three to five-month-old infants prenatally exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 May 2022

Hearing and vision impairment found to be independently associated with cognitive decline

A new nationally representative study published online in the Journal of Alzheimer's Disease Reports found hearing impairment and vision impairment to be independently associated with cognitive impairment.

5 May 2022

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

The glymphatic system enables the flow of cerebrospinal fluid to the brain tissue, particularly during sleep, enabling the fluid to cleanse the tissue and carry accumulated metabolites with it towards the bloodstream during waking hours.

4 May 2022

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

A new study published in the journal Gastroenterology used upper and lower gastrointestinal endoscopy to assess whether gut antigen persistence leads to post-acute COVID-19 in patients with or without post-acute COVID-19 symptoms.

3 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Researchers identify four new target molecules for future personalized MS treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects.

27 Apr 2022

Central Nervous System News and Research

NIH awards first part of $30 million grant to USC team for stroke project

Gabapentin treatment may enhance recovery of movement after a stroke

Researchers analyze the development and genetic profile of brain's immune cells

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

Study explores neurologic complications in pediatric COVID-19 cases

Acoustic holograms enable efficient, selective opening of the blood brain barrier

New drug inhibits growth of the most aggressive meningiomas

Study assesses the effect of extreme heat on workforce health

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Telltale signs of concussions may be found in the gut, study suggests

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

Insight into Neurological Diagnosis in Children

Marine bioactive compounds against SARS-CoV-2

Prenatal exposure to SARS-CoV-2 raises risk of neurological disorders in infants

Hearing and vision impairment found to be independently associated with cognitive decline

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Researchers identify four new target molecules for future personalized MS treatment

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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