Exosomes News and Research

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Researchers discover unknown mechanism that promotes growth and spread of cancer

Tiny vesicles released by tumors cells are taken up by healthy immune cells, causing the immune cells to discharge chemicals that foster cancer-cell growth and spread, according to a study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) and at Children's Hospital in Los Angeles.

11 Jul 2012

Special surface coating for stents to keep them in place

If a person's windpipe is constricted, an operation in which the surgeon inserts a stent to enlarge the trachea is often the only way to relieve their respiratory distress. But this grid-like implant can slip out of position, closing off the windpipe altogether. Researchers are working on a special surface coating for the stents to keep them in place.

9 Jul 2012

Next generation predictive 3D cell toxicity assays to be developed by Medicyte GmbH and Reinnervate Ltd

Two market leading companies in the field of cell based assays and predictive toxicology today announced a new product collaboration. Medicyte (inventors of the upcyte® technology) and Reinnervate (market leaders in the growing field of 3D cell culture) said they will work together to combine their upcyte® and Alvetex®Scaffold technologies to bring next generation cell bases assays to the biopharma and academic research markets.

9 Jul 2012

New insights into role and importance of exosomes and their targeted gene transcripts

In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life.

6 Jul 2012

RXi Pharmaceuticals initiates RXI-109 Phase 1 trial to reduce surgical scars

RXi Pharmaceuticals Corporation today announced that it successfully initiated its first ever clinical study with an RNAi compound, RXI-109, using their proprietary self-delivering RNAi technology.

27 Jun 2012

Cell-free, biodegradable artery graft improves coronary artery bypass surgeries

With the University of Pittsburgh's development of a cell-free, biodegradable artery graft comes a potentially transformative change in coronary artery bypass surgeries: Within 90 days after surgery, the patient will have a regenerated artery with no trace of synthetic graft materials left in the body.

25 Jun 2012

Researchers uncover why ointment and photodynamic therapy cause pain in skin cancer patients

Apply the ointment, light on, light off - that's how easy it is to cure various forms of non-melanoma skin cancer. However, the majority of patients suffer severe pain during the so-termed photodynamic therapy.

23 Jun 2012

DSM XD high cell density process technology granted patents in several countries

DSM Pharmaceutical Products, the custom manufacturing and technology business of Royal DSM N.V., announced today that several countries have granted patents or have given statements of patent allowance to its proprietary XD® high cell density process technology.

19 Jun 2012

New chemical-screening method can discover compounds against HIV

Scientists at The Scripps Research Institute have used a powerful new chemical-screening method to find compounds that inhibit the activity of human immunodeficiency virus (HIV), the virus that causes AIDS.

14 Jun 2012

Human-derived stem cells can spontaneously form optic cups and retina

Human-derived stem cells can spontaneously form the tissue that develops into the part of the eye that allows us to see, according to a study published by Cell Press in the 5th anniversary issue of the journal Cell Stem Cell.

14 Jun 2012

Study documents altruistic behavior by human embryonic stem cells

When most groups of mammalian cells are faced with a shortage of nutrients or oxygen, the phrase "every man for himself" is more apt than "all for one, one for all." Unlike colonies of bacteria, which often cooperate to thrive as a group, mammalian cells have never been observed to help one another out. But a new study led by a researcher at the Stanford University School of Medicine has shown that certain human embryonic stem cells, in times of stress, produce molecules that not only benefit themselves, but also help nearby cells survive.

12 Jun 2012

Fate Therapeutics, BD Biosciences introduce first collaborative iPSC-related product

Fate Therapeutics, Inc. in collaboration with BD Biosciences, a segment of BD (Becton, Dickinson and Company), today announced the introduction of the first induced pluripotent stem cell (iPSC)-related product resulting from the collaboration between the two companies.

From BD (Becton, Dickinson and Company) 11 Jun 2012

Banyan, Amarantus complete collaboration agreement related to TBI development program

Amarantus BioSciences, Inc., a biotechnology company developing new treatments for brain-related disorders including traumatic brain injury (TBI) based on its proprietary anti-apoptotic therapeutic protein known as MANF and Banyan Biomarkers, the leader in developing in vitro diagnostic products to detect TBI, today announced the successful completion of a collaboration agreement initiated in November 2011 to evaluate MANF's potential as a disease-modifying agent for the treatment of TBI.

8 Jun 2012

InVitria receives new SBIR grant from NIAID

Ventria Bioscience today announced that its non-therapeutic products division InVitria has been awarded a new Small Business Innovation Research Program (SBIR) grant from the National Institutes of Health, National Institute of Allergy and Infectious Diseases.

6 Jun 2012

Researchers uncover cellular basis for age-related breast cancer vulnerability

It is well-known that the risks of breast cancer increase dramatically for women over the age of 50, but what takes place at the cellular level to cause this increase has been a mystery. Some answers and the possibility of preventative measures in the future are provided in a new study by researchers at the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory.

5 Jun 2012

Secreted vesicles play role in spread of cancer

Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called "soil and seed" theory of 1889. New details that could help shed light on this hypothesis have been provided by a team of researchers from Weill Cornell Medical College, Memorial Sloan-Kettering Cancer Center, and their collaborators, proposing a new mechanism controlling cancer metastasis that offers fresh diagnostic and treatment potential.

29 May 2012

Exosomes News and Research

Researchers discover unknown mechanism that promotes growth and spread of cancer

Special surface coating for stents to keep them in place

Next generation predictive 3D cell toxicity assays to be developed by Medicyte GmbH and Reinnervate Ltd

New insights into role and importance of exosomes and their targeted gene transcripts

RXi Pharmaceuticals initiates RXI-109 Phase 1 trial to reduce surgical scars

Cell-free, biodegradable artery graft improves coronary artery bypass surgeries

Researchers uncover why ointment and photodynamic therapy cause pain in skin cancer patients

DSM XD high cell density process technology granted patents in several countries

New chemical-screening method can discover compounds against HIV

Human-derived stem cells can spontaneously form optic cups and retina

Study documents altruistic behavior by human embryonic stem cells

Fate Therapeutics, BD Biosciences introduce first collaborative iPSC-related product

Banyan, Amarantus complete collaboration agreement related to TBI development program

InVitria receives new SBIR grant from NIAID

Researchers uncover cellular basis for age-related breast cancer vulnerability

Secreted vesicles play role in spread of cancer

Astrocytes appear to retaliate against AD

Inhibition of PBEF could be potential therapeutic target for pulmonary hypertension

Vaccination studies from Mercer University to be unveiled at AAPS’ NBC

Metformin blocks uveitis in laboratory rats

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