Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

NOXXON commences NOX-H94 Phase IIa trial to treat anemia of chronic disease

NOXXON Pharma today announced the treatment of the first patients in a Phase IIa clinical trial of its anti-hepcidin Spiegelmer NOX-H94 to treat anemia associated with chronic disease.

5 Dec 2012

Diabetes tests: an interview with Dr. Danielle Stowasser

Diabetes is a serious condition that causes high levels of glucose (a type of sugar) in the blood. There are three main types of diabetes: type 1 and type 2 diabetes, which are lifelong conditions, and gestational diabetes, which only occurs in women during pregnancy.

3 Dec 2012

DaVita acquires Tulips Dialysis Centre; opens two new joint venture centers in Malaysia

DaVita, a leading provider of kidney care services for those diagnosed with chronic kidney disease (CKD), today announced the acquisition of Tulips Dialysis Centre and has opened two new joint venture centers in Malaysia.

3 Dec 2012

Tour DaVita helps raise $0.9M to support 2012 Bridge of Life

DaVita, a division of DaVita HealthCare Partners, Inc. and a leading provider of kidney care services announced that its annual charity bike ride, Tour DaVita, raised $900,000 to support Bridge of Life—DaVita Medical MissionsTM in 2012.

1 Dec 2012

Coronary artery bypass grafting safe for dialysis patients

Among the two available procedures for opening blocked arteries surrounding the heart, one appears to be safer than the other for dialysis patients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

30 Nov 2012

Diabetes education critical for uncontrolled high blood sugar people with cancer

When people with Type 2 diabetes are diagnosed with cancer -- a disease for which they are at higher risk -- they ignore their diabetes care to focus on cancer treatment, according to new Northwestern Medicine- research. But uncontrolled high blood sugar is more likely to kill them and impairs their immune system's ability to fight cancer.

30 Nov 2012

African Americans experience faster progression of CKD during later stages

Among individuals with chronic kidney disease (CKD), African Americans experience faster progression of the disease during later stages compared with other races, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

30 Nov 2012

Topically applied simvastatin enhances wound recovery in diabetic mice

Delayed wound healing is a major complication of diabetes because the physiological changes in tissues and cells impair the wound healing process. This can result in additional disease outcomes such as diabetic foot ulcer, a significant cause of morbidity in the growing population of diabetic patients. A new study has found that topically applied simvastatin accelerates wound healing in diabetic mice, suggesting important implications for humans with diabetes.

28 Nov 2012

Diabetes can remit after gastric bypass surgery

After gastric bypass surgery, diabetes goes away for some people-often even before they lose much weight. So does that mean gastric surgery "cures" diabetes? Not necessarily, according to the largest community-based study of long-term diabetes outcomes after bariatric surgery.

27 Nov 2012

Kidney disease measures on mortality, ESRD unaffected by age

Regardless of age, estimated glomerular filtration rate and high albuminuria are linked to death and end-stage renal disease, say US scientists who found a lower relative but higher absolute mortality risk difference at older age.

23 Nov 2012

Researchers create 3D map of rod sensory cilium architecture affected by mutation

Using a new technique called cryo-electron tomography, two research teams at Baylor College of Medicine (www.bcm.edu) have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.

23 Nov 2012

Scars mark hypertension risk in vesicoureteral reflux

Renal scarring associated with vesicoureteral reflux is a significant risk factor for developing hypertension, shows a study of pediatric patients.

21 Nov 2012

Rituximab may help patients with aPL-related clinical problems

Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies (aPLs) who suffer from aPL-related clinical problems that do not respond to anticoagulation, such as cardiac disease and kidney disease, according to a new study by rheumatology researchers at Hospital for Special Surgery. The study appears online ahead of print, in the journal Arthritis and Rheumatism.

21 Nov 2012

Texting service helps patients reduce their blood pressure

A simple telehealth intervention could be an effective way to reduce blood pressure in patients, research suggests.

19 Nov 2012

Biomolecular imaging: an interview with Professor Roger Reddel

The reason Children’s Medical Research Institute (CMRI) exists is to find ways to treat or prevent childhood disease. Our research programs are focussed on the areas of cancer cell growth, nerve cell signalling, embryology and gene therapy. These four programs have a shared aim of translating novel findings into new treatments for the benefit of families everywhere.

19 Nov 2012

New €6 million European project to address complications associated with diabetes

NUI Galway has been awarded a major new €6 million European project, designed to address complications associated with diabetes. The research project will examine the ability of stem cells to safely control glucose levels and alleviate the damage caused by six different diabetic complications.

19 Nov 2012

Decreased cognitive functioning associated with deterioration in kidney function

Decreased kidney function is associated with decreased cognitive functioning in areas such as global cognitive ability, abstract reasoning and verbal memory, according to a study led by Temple University. This is the first study describing change in multiple domains of cognitive functioning in order to determine which specific abilities are most affected in individuals with impaired renal function.

19 Nov 2012

People with diabetes need a plan to stay healthy during holiday season: Harris Health System

A figurative mine field of savory dishes and desserts await many this holiday season, from pumpkin pies topped with whipped cream, green bean and mushroom casseroles, pork tamales, cranberries and cornbread dressing to fruit salads and oven-roasted turkey.

17 Nov 2012

Cinacalcet failure raises trial conduct issues

The oral calcimimetic agent, cinacalcet, has been found to have no significant effect on cardiovascular events or death in patients with chronic kidney disease in a randomized controlled trial.

16 Nov 2012

Caterpillar fungi may benefit asthma patients

Research shows that cordycepin, extracted from a group of rare parasitic caterpillar fungi of the genus Cordyceps, has unusual anti-inflammatory properties that may make it a good candidate for treating conditions such as asthma and rheumatoid arthritis.

16 Nov 2012