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UIC discovery may lead to new treatments for alcohol use disorder and depression

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.

14 Jun 2021

Virginia Tech researcher receives $2.2 million to advance study on small 'fat burning' molecules

The liver is the most resilient organ in the human body. It can remove toxins from the bloodstream, recycle red blood cells, maintain sugar levels, and it can even regenerate itself. But, when a large amount of fat builds up in the liver, it becomes too inflamed to perform its crucial duties.

14 Jun 2021

Kirigami-inspired stent to improve drug delivery for diseases that affect tubular organs

Diseases that affect tubular structures in the body, such as the gastrointestinal (GI) system, vasculature and airway, present a unique challenge for delivering local treatments.

14 Jun 2021

SBP scientist receives $1.9 million from NHLBI for atrial fibrillation research

Sanford Burnham Prebys Assistant Professor Alexandre Colas has been awarded $1.9 million by the National Heart, Lung, and Blood Institute at the National Institutes of Health to discover drugs that restore normal cardiac rhythm in atrial fibrillation.

14 Jun 2021

UCSF launches new initiative to propel the development of living therapeutics

UC San Francisco is launching a new initiative to propel the development of living therapeutics - a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease - and bring them quickly to patients.

14 Jun 2021

Fatty acid binding site on SARS-CoV-2 spike triggers spike monomer crosstalk that is key to infectivity

A new study, released as a preprint on the bioRxiv* server, examines the role played by a fatty acid called linoleic acid (LA) that attaches at a binding site near the receptor-binding domain (RBD) of the spike protein. The spike exists as a homotrimer in open or closed conformations. In the former, at least one RBD points upwards.

14 Jun 2021

Novel computer system can help inform future therapies for patients with inherited heart disease

An integrated, genomic computer system for precision cardiology has been created using clinical data that can help inform medical and surgical decisions to support future therapies for patients with inherited heart disease.

14 Jun 2021

Joint ICMRA and WHO statement explains how COVID-19 vaccines are regulated for safety, effectiveness

Healthcare professionals and public health authorities have a central role in discussing vaccination against COVID-19 with their patients.

13 Jun 2021

Role of traditional medicine against SARS-CoV-2

A group of researchers at Kannur University reviewed selected papers and in silico work on potential drug leads that could be used to manage COVID-19.

13 Jun 2021

An analysis links COVID-19 to brain microvascular injury and inflammation

The ongoing COVID-19 pandemic is caused by the severe acute respiratory syndrome-2 (SARS-CoV-2), an RNA virus that belongs to the family Coronaviridae. According to research, coronavirus disease 2019 (COVID-19) patients often suffer from neurological disorders like strokes, lost taste or smell, memory loss, confusion, and delirium.

13 Jun 2021

New technique uses high-throughput sequencing to obtain ultra-high-resolution images of gene expression

The 30,000 or so genes making up the human genome contain the instructions vital to life. Yet each of our cells expresses only a subset of these genes in their daily functioning. The difference between a heart cell and a liver cell, for example, is determined by which genes are expressed--and the correct expression of genes can mean the difference between health and disease.

11 Jun 2021

New 3D printing process helps build tailor-make artificial body parts, other medical devices

Using a new 3D printing process, University of Nottingham researchers have discovered how to tailor-make artificial body parts and other medical devices with built-in functionality that offers better shape and durability, while cutting the risk of bacterial infection at the same time.

11 Jun 2021

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Metformin is a widely prescribed blood sugar-lowering drug. It is often used as an early therapy (in combination with diet and lifestyle changes) for type 2 diabetes, which afflicts more than 34 million Americans.

11 Jun 2021

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy.

11 Jun 2021

New framework establishes safe thresholds for antimicrobials

Researchers have made progress towards a G7 commitment to establish safe standards for the release of antimicrobials into the environment, by developing a new framework that establishes safe thresholds.

11 Jun 2021

Study shows how XRCC1 gene untangles proteins that trigger cancerous tumors

Even on a good day, DNA is constantly getting damaged. Nicks, scratches, breaks: the delicate strands that carry life's genetic code take a beating as they jumble about in the course of their work. If left untreated, errors accumulate, with fatal consequences -- such as cancerous tumors -- for the cell and the organism.

11 Jun 2021

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

AP-HP Greater Paris University Hospitals, the leading European clinical trial center with the largest amount of healthcare data in France dedicated to research and Owkin, a startup pioneering Federated Learning and AI technologies for medical research and clinical development, announced the recent results of their ongoing strategic collaboration at ASCO 2021.

10 Jun 2021

Drugs News and Research

UIC discovery may lead to new treatments for alcohol use disorder and depression

Virginia Tech researcher receives $2.2 million to advance study on small 'fat burning' molecules

Kirigami-inspired stent to improve drug delivery for diseases that affect tubular organs

SBP scientist receives $1.9 million from NHLBI for atrial fibrillation research

UCSF launches new initiative to propel the development of living therapeutics

Fatty acid binding site on SARS-CoV-2 spike triggers spike monomer crosstalk that is key to infectivity

Novel computer system can help inform future therapies for patients with inherited heart disease

Joint ICMRA and WHO statement explains how COVID-19 vaccines are regulated for safety, effectiveness

Role of traditional medicine against SARS-CoV-2

An analysis links COVID-19 to brain microvascular injury and inflammation

New technique uses high-throughput sequencing to obtain ultra-high-resolution images of gene expression

New 3D printing process helps build tailor-make artificial body parts, other medical devices

Metformin prevents pulmonary or lung inflammation in animals infected with SARS-CoV-2

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

New framework establishes safe thresholds for antimicrobials

Study shows how XRCC1 gene untangles proteins that trigger cancerous tumors

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

New open-source tool designed to predict drug overdose mortality in the U.S.

Study reveals new insights into how genes are regulated in dementia

Common antidepressant drugs help the immune system to attack tumors in mice

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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