Immune System News and Research

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Study reveals how nitric oxide impedes growth of ‘snail fever’ parasite

Bilharzia, caused by a parasitic worm found in freshwater called Schistosoma, infects around 200 million people globally and its advance can lead to death, especially in children in developing countries.

14 Sep 2017

Researchers overcome major stumbling blocks in developing HIV vaccine

An international team of researchers has demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV: the ability to generate immune cells that stay in circulation long enough to respond to and stop virus infection.

13 Sep 2017

New testing regime could speed up diagnosis and treatment of SCID in infants

Babies born with Severe Combined Immune Deficiency (SCID) syndrome are defenceless against bacterial and viral infections that would be virtually harmless to most healthy people. If untreated, SCID is often fatal within a baby's first year of life.

13 Sep 2017

Immunotherapy could help some breast cancer patients based on genetic changes in their tumors

Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumors, researchers at the Wellcome Trust Sanger Institute and their collaborators find.

13 Sep 2017

Study uncovers how inflammation contributes to key feature of diabetes

A new study by researchers at the University of Maryland School of Medicine has uncovered how inflammation contributes to a key feature of diabetes, the body's inability to metabolize glucose, a condition known as insulin resistance.

12 Sep 2017

Australian researchers make ultimate move in the battle against melanoma

A team of Australian researchers has made the ultimate move in the battle to beat melanoma, successfully trialing a combination of new treatments to stop the disease in its tracks and prevent it from spreading or metastasizing to distant organs.

12 Sep 2017

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

Oncology researchers studying high-risk children's cancers have identified a protein that offers a likely target for immunotherapy--harnessing the immune system in medical treatments. In cell cultures and animal models, a potent drug attached to an antibody selectively zeroes in on cancer cells without harming healthy cells.

11 Sep 2017

Campylobacter infection outbreak linked to puppies

There is a warning about a multi-state outbreak of human Campylobacter infections that seemed to have originated from the puppies sold through Petland, a national pet store chain.

11 Sep 2017

Immune response to parasite varies depending on what time infection occurs, study shows

Does the time of day matter when our body is infected by a parasite? According to new research from McGill University, it matters a great deal.

11 Sep 2017

Study: Lupus affects Hispanic, Asian women in Manhattan more frequently than white women

Within Manhattan's diverse population, the chronic and often debilitating autoimmune disease lupus affects Hispanic and Asian women more frequently than white women, according to a new study led by investigators at NYU School of Medicine.

11 Sep 2017

Regulatory T-cells can support fat depots in dealing with environmental challenges

Immunosuppressive regulatory T-cells play an important role in the functioning of adipose tissue. This is the discovery of scientists from the Helmholtz Diabetes Center at Helmholtz Zentrum München and the Technical University of Munich.

11 Sep 2017

Combination treatment provides positive results for people with advanced melanoma

In a two-year UCLA-led study, nearly two-thirds of people with advanced melanoma responded positively to a treatment that combines the immunotherapy drug pembrolizumab with a herpes virus called talimogene laherpareovec, or T-VEC.

8 Sep 2017

CWRU professor wins $3.9 million NIH grant to identify countermeasures against chemical hazards

Kurt Lu, MD, assistant professor of dermatology at Case Western Reserve University School of Medicine, has received a five year, $3.9 million grant from the National Institutes of Health to expand countermeasures against chemical threats, including mustard gas and mustard-related compounds.

7 Sep 2017

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Cancer immunotherapy drugs only work for a minority of patients, but a generic drug now used to increase blood flow may be able to improve those odds, a study by Columbia University Medical Center researchers suggests.

7 Sep 2017

Differentiating sepsis and systemic inflammatory response syndrome using biomarkers

Firstly, it is necessary to make a distinction between systemic inflammation and Systemic Inflammatory Response Syndrome (SIRS). SIRS consists of changes in clinical signs including an abnormal body temperature, increased heart rate, increased respiratory rate, an abnormal white cell count (either decreased or elevated), or an increase in band neutrophils.

7 Sep 2017

Discovery of sugar 'warehouse' provides new metabolic target to regulate immune activity

A surprising discovery that immune cells possess an internal warehouse of glycogen used to activate immune responses could help to increase immune activity in vaccines or suppress immune reactions in autoimmune disease or hyper-inflammatory conditions.

6 Sep 2017

Combined PET/CT scanning could identify melanoma patients' response to ICI therapy

Advanced melanoma, a type of skin cancer that has spread to other areas of the body, has a poor prognosis, but immune checkpoint inhibitor therapy can be effective for some patients. Research highlighted in the featured article of the September issue of The Journal of Nuclear Medicine demonstrates that combined positron emission tomography/computed tomography (PET/CT) scanning early in treatment could identify whether the therapy will benefit a particular patient.

6 Sep 2017

Another way for anti-vaxxers to skip shots for schoolkids: A doctor’s note

Dr. Tara Zandvliet was inundated with calls and emails from parents last year, after California passed a law nixing personal beliefs as an exemption from school vaccinations. Suddenly, many parents sought exemptions for medical reasons.

5 Sep 2017

MIT study offers new approach to evaluate risk of preterm birth

Up to 18 percent of babies born worldwide arrive before they are full-term, defined as 37 weeks of gestation. About 1 million of those babies do not survive, and those who do can face developmental problems such as impaired vision or hearing, defects in the heart or lungs, or cognitive impairments.

5 Sep 2017

Research provides novel insights into bacterial toxins

A toxin produced by a bacterium that causes urinary tract infections is related to, yet different in key ways from, the toxin that causes whooping cough, according to new research.

5 Sep 2017

Immune System News and Research

Study reveals how nitric oxide impedes growth of ‘snail fever’ parasite

Researchers overcome major stumbling blocks in developing HIV vaccine

New testing regime could speed up diagnosis and treatment of SCID in infants

Immunotherapy could help some breast cancer patients based on genetic changes in their tumors

Study uncovers how inflammation contributes to key feature of diabetes

Australian researchers make ultimate move in the battle against melanoma

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

Campylobacter infection outbreak linked to puppies

Immune response to parasite varies depending on what time infection occurs, study shows

Study: Lupus affects Hispanic, Asian women in Manhattan more frequently than white women

Regulatory T-cells can support fat depots in dealing with environmental challenges

Combination treatment provides positive results for people with advanced melanoma

CWRU professor wins $3.9 million NIH grant to identify countermeasures against chemical hazards

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Differentiating sepsis and systemic inflammatory response syndrome using biomarkers

Discovery of sugar 'warehouse' provides new metabolic target to regulate immune activity

Combined PET/CT scanning could identify melanoma patients' response to ICI therapy

Another way for anti-vaxxers to skip shots for schoolkids: A doctor’s note

MIT study offers new approach to evaluate risk of preterm birth

Research provides novel insights into bacterial toxins

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