B Cell News and Research

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Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Less than 20% of diagnosed breast cancers are designated "triple-negative," lacking three types of receptors often found in other breast cancer types.

30 Nov 2022

The effect of evolutionary changes in prolonged SARS-CoV-2 infection in an immunosuppressed individual due to advanced HIV

Researchers assessed the impact of SARS-CoV-2 infection on cell death and fusion in an immunocompromised host.

30 Nov 2022

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

30 Nov 2022

Inactivation of previously unknown gene found to be a likely culprit in the onset of pancreatic cancer

New research out of VCU Massey Cancer Center points to the inactivation of a previously unidentified gene as a likely culprit in the development of pancreatic cancer.

30 Nov 2022

New guidelines for designing synthetic molecules that block interaction between two proteins

Inside cells, proteins constantly interact with each other to carry out different functions. For some diseases in which these functions are altered, blocking the binding between two or more proteins emerges as a possible therapeutic approach.

30 Nov 2022

Plasma from vaccinated and COVID-19 convalescent subjects as passive immunotherapy against the new Omicron BQ.1.1, XBB, and BF.7 variants

Researchers systematically reviewed SARS-CoV-2 Omicron BQ.1.1 neutralization data from individual patient samples.

30 Nov 2022

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Researchers investigated whether severe COVID-19 patients exhibited inflammation and immune activation three months after hospitalization and explored the associations among COVID-19 severity, long COVID, and immune activation.

30 Nov 2022

Broadly cross-reactive antibodies that protect from SARS-CoV-2 variants are revealed by virus coldspot-driven discovery

A recent study identified neutralizing antibodies against conserved SARS-CoV-2 epitopes.

30 Nov 2022

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Researchers estimated the incidence of new-onset diabetes in survivors of coronavirus disease 2019 (COVID-19) employing random-effects meta-analyses using the generic inverse variance method.

30 Nov 2022

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

To commemorate World AIDS Day, News Medical spoke to Dr. Larry Corey, an internationally renowned expert in virology, immunology, and vaccine development, and the former president and director of Fred Hutch, about his work within the field of HIV/AIDS research and vaccine development.

30 Nov 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Bioorthogonal system for targeted release of nitrite ions into cancer cells

A team of researchers writing in the journal Angewandte Chemie has developed a bioorthogonal molecular system for the targeted introduction of nitrite ions into cells.

30 Nov 2022

Lysis and hypotonic sonication buffers for ChIP assays

Offering complete disruption of cytoplasmic and nuclear membranes, Porvair Sciences Chromatrap® buffer chemistries are optimised for sonication and enzymatic shearing.

From Porvair Sciences Limited 29 Nov 2022

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Unique new material developed at University of Limerick in Ireland has shown significant promise in the treatment of spinal cord injury.

29 Nov 2022

Cryoablation is more effective than heat-based treatment for some small kidney cancers

For patients with early-stage renal cell carcinomas (RCCs) that measure between 3 and 4 centimeters, a procedure that destroys the cancer by freezing – called cryoablation – yields a lower-risk of cancer-related death compared to heat-based thermal ablation, reports a preliminary study in The Journal of Urology®, an Official Journal of the American Urological Association.

29 Nov 2022

B Cell News and Research

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

The effect of evolutionary changes in prolonged SARS-CoV-2 infection in an immunosuppressed individual due to advanced HIV

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Inactivation of previously unknown gene found to be a likely culprit in the onset of pancreatic cancer

New guidelines for designing synthetic molecules that block interaction between two proteins

Plasma from vaccinated and COVID-19 convalescent subjects as passive immunotherapy against the new Omicron BQ.1.1, XBB, and BF.7 variants

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Broadly cross-reactive antibodies that protect from SARS-CoV-2 variants are revealed by virus coldspot-driven discovery

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

The effects of mechanical forces on musculoskeletal cells and tissues

Bioorthogonal system for targeted release of nitrite ions into cancer cells

Lysis and hypotonic sonication buffers for ChIP assays

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Cryoablation is more effective than heat-based treatment for some small kidney cancers

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Monkeypox renamed "mpox" in an effort to combat stigma

Newly discovered material can aid healing of hard-to-treat diabetic wounds

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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