Immune System News and Research

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STING signaling pathway induces apoptosis in T cells

EPFL scientists show that the STING signaling pathway, which helps coordinate the innate immune system, causes cell death in T cells of the adaptive immune system. This “killing” effect includes cancerous T cells, and has implications for treating T cell-derived cancers.

5 Sep 2017

Zika virus may one day be effective treatment for deadly brain cancer

While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment for glioblastoma, a deadly form of brain cancer.

5 Sep 2017

University and pediatric hospital work together to improve lives of children with epilepsy

Since 2010, investigators and clinicians at Aston University and Birmingham Children's Hospital have worked together to try and improve the lives of children with difficult to treat forms of epilepsy.

5 Sep 2017

Breastfeeding may protect children from asthma exacerbations later in life

In a Pediatric Allergy and Immunology analysis of children with asthma, those who had been breastfed had a 45% lower risk of asthma exacerbations later in life compared with children who had not been breastfed.

1 Sep 2017

Link found between fetal genes and risk of preeclampsia in mother

For the first time, a relationship has been found between fetal genes and the risk of preeclampsia in the mother.

31 Aug 2017

New research shows estrogen synthesis may fight off infection-induced neuroinflammation

The chemical best-known as a female reproductive hormone--estrogen--could help fight off neurodegenerative conditions and diseases in the future.

31 Aug 2017

Beta blockers capable of reducing stress signaling may enhance effectiveness of immunotherapy

While the development of therapies designed to block "checkpoints" within the immune system has been one of the most exciting and noteworthy advances in cancer research in recent years, it's also been one of the most puzzling, leaving researchers to ask: Why don't these new therapies work for more patients, and why is their efficacy in controlling cancerous tumors often short-lived? A research team from Roswell Park Cancer Institute has shown that at least one answer - and an excellent opportunity for unleashing the full potential of these promising immunotherapies - may lie in the body's "fight or flight" reaction to stressors and in drugs already widely used to control and temporarily disable this stress response.

31 Aug 2017

Researcher uses gold nanoparticles and lasers to target bladder cancer

A University of Colorado Cancer Center study takes a new approach to killing cancer: Why not fry it into oblivion with vibrating gold nanoparticles? "But what about the frickin' lasers?" you may ask. Don't worry. There are lasers. And bioluminescence too.

31 Aug 2017

Olfactory tissue regeneration requires inflammatory processes that create loss of smell

In a mouse study designed to understand how chronic inflammation in sinusitis damages the sense of smell, scientists at Johns Hopkins say they were surprised to learn that the regeneration of olfactory tissue requires some of the same inflammatory processes and chemicals that create injury and loss of smell in the first place.

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

‘Liquid biopsies’ may help predict prognosis of early-stage lung cancer patients

Cancer cells obtained from a blood test may be able to predict how early-stage lung cancer patients will fare, a team from the University of Michigan has shown.

30 Aug 2017

Pioneering cancer gene therapy gets green light — and $475,000 price tag

The country's first approved gene therapy — approved Wednesday to fight leukemia that resists standard therapies — will cost $475,000 for a one-time treatment, its manufacturer announced.

30 Aug 2017

New biomedical tool using nanoparticles could improve therapies for many diseases

A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseases - including cancer, diabetes and HIV - faster and cheaper to develop, and more customizable.

30 Aug 2017

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

An international study of integrated HHV-6 has discovered that a small number of human ancestors, one from about 24,000 years ago, have been responsible for transmitting ancient strains of the virus to individuals today - affecting about a million people in the UK alone.

30 Aug 2017

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists have discovered a network of genes and genetic regulatory elements in the lining of the intestines that has stayed remarkably the same from fishes to humans. Many of these genes are linked to human illnesses, such as inflammatory bowel diseases, diabetes and obesity.

30 Aug 2017

Immune System News and Research

STING signaling pathway induces apoptosis in T cells

Zika virus may one day be effective treatment for deadly brain cancer

University and pediatric hospital work together to improve lives of children with epilepsy

Breastfeeding may protect children from asthma exacerbations later in life

Link found between fetal genes and risk of preeclampsia in mother

New research shows estrogen synthesis may fight off infection-induced neuroinflammation

Beta blockers capable of reducing stress signaling may enhance effectiveness of immunotherapy

Researcher uses gold nanoparticles and lasers to target bladder cancer

Olfactory tissue regeneration requires inflammatory processes that create loss of smell

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

‘Liquid biopsies’ may help predict prognosis of early-stage lung cancer patients

Pioneering cancer gene therapy gets green light — and $475,000 price tag

New biomedical tool using nanoparticles could improve therapies for many diseases

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Heat therapy could be promising treatment to help fight against cancer, autoimmune problems

Researchers develop new approach to efficiently produce versatile antibody therapies

Immunotherapy that uses existing cancer drugs in a new way delivers promising results

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

Spaceflight causes many significant changes in the human body, research shows

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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