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Study examines benefits of SGLT2 inhibitors in individuals with type 1 diabetes

In addition to lowering blood sugar levels, diabetes drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors can provide kidney- and cardiovascular-related benefits for people with type 2 diabetes.

7 Nov 2021

Deletion of ABI3 gene in the brain may increase risk of developing Alzheimer’s disease

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them.

7 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Anemia is a common and sometimes debilitating problem among patients with chronic kidney disease (CKD). Anemia can occur when the kidneys become damaged, limiting the production of erythropoietin (EPO) - a hormone that signals to the body to make red blood cells.

7 Nov 2021

Results of high-impact clinical trials could affect kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online at ASN Kidney Week 2021 November 4–November 7.

7 Nov 2021

Study opens a window for new therapeutic approaches to ovarian cancer

A Ludwig Cancer Research study has uncovered a cellular interaction that is essential to the ability of the immune system's cytotoxic T lymphocytes to destroy ovarian tumors and shown that its engagement could help determine the efficacy of checkpoint blockade immunotherapy in a variety of cancers.

6 Nov 2021

Key link between chronic stress and cancer discovered

Stress can have a significant negative effect on health, but our understanding of how stress impacts the development and progression of cancer is just beginning.

6 Nov 2021

Ibrutinib plus standard chemotherapy effective in younger patients with diffuse large B-cell lymphoma

Younger patients with specific genetic subtypes of non-GCB DLBCL, called MCD and N1, had an exceptional response to the treatment combination.

5 Nov 2021

Return to school testing initiative addresses the needs of underserved communities

Safe, in-person school during the COVID-19 pandemic requires research that involves community engagement in underserved or vulnerable areas of the United States, writes Alison Cernich, Ph.D., deputy director of NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and colleagues.

5 Nov 2021

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Many people develop Alzheimer's or other forms of dementia as they get older. However, others remain sharp well into old age, even if their brains show underlying signs of neurodegeneration.

3 Nov 2021

Deadly parasite could potentially be used to treat various types of cancers

Scientists have discovered that a deadly parasite, known to cause ill health in pregnant women and immunocompromised patients, could potentially be used to treat various types of tumors.

3 Nov 2021

CHOP-led network receives NIH-supported resources to unlock mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia (CHOP). The Children's Brain Tumor Network (CBTN), a multi-institutional brain tumor research program with its operations center housed at D3b, has collected tumor samples from patients all over the world.

3 Nov 2021

Cycling JAK inhibitors can be effective for treating people with difficult-to-treat rheumatoid arthritis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that people with difficult-to-treat rheumatoid arthritis who do not have success with one Janus kinase inhibitor (JAK inhibitor) can achieve success either cycling to other JAKi medications or switching to a biologic drug.

2 Nov 2021

RA patients taking glucocorticoids or B-cell therapies may have worse COVID-19 vaccine response

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that people with chronic inflammatory diseases, such as rheumatoid arthritis (RA), who take immunosuppressive therapy appear to have an impaired immunity response to SARS-CoV-2, the coronavirus that causes COVID-19, vaccines. Patients currently on glucocorticoids or B-cell depleting therapy appear to have an even more severely impeded vaccine response.

2 Nov 2021

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that heart rate monitoring is a feasible, accurate tool to check for heart rhythm abnormalities in the fetuses of pregnant women with anti-Ro/SSA antibodies.

2 Nov 2021

Immunocompromised patients using rituximab could benefit from third COVID-19 booster vaccine

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows immunocompromised patients using rituximab (a drug used to treat diseases like rheumatoid arthritis) were able to produce antibodies against COVID-19 (seroconvert) after receiving a third COVID-19 vaccine dose, even if there was no development of the antibody after the first two doses of the vaccine.

2 Nov 2021

Scientists discover key component of cellular malfunction that contributes to growth of tumors

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

2 Nov 2021

IBD patients produce a strong antibody response to COVID-19 vaccination, finds study

Researchers at Cedars-Sinai found that patients with inflammatory bowel disease (IBD)─whose treatment can weaken the immune system─produced a strong antibody response to COVID-19 vaccination.

2 Nov 2021

Study shows cognitive effects of ready-to-use enhanced therapeutic food in malnourished children

A nutritional supplement popular in the U.S. and added to some types of yogurt, milk and infant formula can significantly improve cognition in severely malnourished children, according to a study led by researchers at Washington University School of Medicine in St. Louis.

2 Nov 2021

Therapy News and Research

Study examines benefits of SGLT2 inhibitors in individuals with type 1 diabetes

Deletion of ABI3 gene in the brain may increase risk of developing Alzheimer’s disease

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Results of high-impact clinical trials could affect kidney-related medical care

Study opens a window for new therapeutic approaches to ovarian cancer

Key link between chronic stress and cancer discovered

Ibrutinib plus standard chemotherapy effective in younger patients with diffuse large B-cell lymphoma

Return to school testing initiative addresses the needs of underserved communities

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Deadly parasite could potentially be used to treat various types of cancers

CHOP-led network receives NIH-supported resources to unlock mysteries behind pediatric brain tumors

Cycling JAK inhibitors can be effective for treating people with difficult-to-treat rheumatoid arthritis

RA patients taking glucocorticoids or B-cell therapies may have worse COVID-19 vaccine response

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

Immunocompromised patients using rituximab could benefit from third COVID-19 booster vaccine

Scientists discover key component of cellular malfunction that contributes to growth of tumors

IBD patients produce a strong antibody response to COVID-19 vaccination, finds study

Study shows cognitive effects of ready-to-use enhanced therapeutic food in malnourished children

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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