Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has identified an epidermal growth factor receptor aberrantly active in approximately a third of the 250 human pancreatic cancers studied.

20 Apr 2009

New biomarker may predict aggressiveness of chronic lymphocytic leukemia

Scientists at the University of California, San Diego and the Moores UCSD Cancer Center have evidence of a potential new biomarker to predict the aggressiveness of an often difficult-to-treat form of leukemia.

20 Apr 2009

Coffee, caffeine and amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages key neurons in the brain and spinal cord.

20 Apr 2009

Computational model examines the pathways of Alzheimer's that strikes at the young

Alzheimer's disease (AD) is a tragic disease that robs an individual of their memory and mental capacity.

20 Apr 2009

Survival mode that protects cells when oxygen is low also slows aging

A biochemical pathway that helps keep cells alive when oxygen is low also plays a role in longevity and resistance against some diseases of old age, according to a report to be published April 16 in the journal Science.

16 Apr 2009

New insights Huntington disease development

A global analysis of brain proteins over a 10-week period in a mouse model of Huntington Disease has revealed some new insights into this complex neurodegenerative disorder.

16 Apr 2009

Autopsy study links prostate cancer to single rogue cell

One cell…one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer.

16 Apr 2009

Autopsy study links prostate cancer to single rogue cell

One cell...one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer. Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease. Culling information from autopsies, their study points to a set of genetic defects in a single cell that are different for each person's cancer.

16 Apr 2009

Gene therapy for muscular dystrophy a step closer

Researchers have cleared a safety hurdle in efforts to develop a gene therapy for a form of muscular dystrophy that disables patients by gradually weakening muscles near the hips and shoulders.

15 Apr 2009

The DECIPHER database - revolutionising clinical practice and genetic research

Today - five years after the inception of the DECIPHER database - researchers have published a report that reveals the developing role of the database in revolutionising both clinical practice and genetic research.

15 Apr 2009

PET/CT imaging shows if single cycle of chemo is working

Oncologists often have to wait months before they can determine whether a treatment is working.

14 Apr 2009

New minimally invasive ultrasound-guided biopsy method allows improved diagnosis of endometrial disease

A procedure used in conjunction with a vaginal ultrasound might make it easier to visualize and diagnose diseases in the lining of the uterus, researchers at UT Southwestern Medical Center have found.

14 Apr 2009

'Good' brown baby fat can ward off obesity and type 2 diabetes

Scientists in the United States say people who hang on to their baby fat may be protected from developing type 2 diabetes and becoming obese - obesity is a major risk factor for type 2 diabetes.

13 Apr 2009

New alternative to biopsy detects subtle changes in cancer cells

A drop of blood or a chunk of tissue smaller than the period at the end of this sentence may one day be all that is necessary to diagnose cancers and assess their response to treatment, say researchers at the Stanford University School of Medicine.

12 Apr 2009

Gene fusion discovery may lead to improved prostate cancer test

A newly discovered gene fusion is highly expressed in a subset of prostate cancers, according to a study by researchers at Weill Cornell Medical College.

12 Apr 2009

Research finds active brown fat in adult humans

Researchers at the Joslin Diabetes Center have demonstrated that adult humans still have a type of "good" fat previously believed to be present only in babies and children.

9 Apr 2009

MRI-based method holds promise for predicting treatment outcomes in patients with atrial fibrillation

University of Utah researchers have found that delayed-enhancement magnetic resonance imaging (DE-MRI) holds promise for predicting treatment outcomes and measuring disease progression for patients with atrial fibrillation (AF), a little known heart rhythm disorder that affects more than 3.5 million Americans and causes more than 66,000 deaths a year.

8 Apr 2009

Inflammatory chemokine may explain diseases that come with obesity

An inflammatory factor already linked to several diseases, including pulmonary disease, lung cancer, and arthritis, may also be responsible for the insulin resistance that comes with obesity, according to a new study published in the April issue of Cell Metabolism.

8 Apr 2009

Colonoscopy versus virtual colonoscopy

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

2 Apr 2009

Discovery of marker for severity in adult brain cancer

Researchers at UT Southwestern Medical Center have identified a new biological indicator that may help identify which brain-cancer patients have the most aggressive forms of the disease.

1 Apr 2009