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Shorter treatment regimen found to be effective for treating TB

Tuberculosis (TB) is a deadly infection that occurs in every part of the world. The standard treatment for TB, a six-month multidrug regimen, has not changed in more than 40 years. Patients can find it difficult to complete the lengthy regimen, making it more likely that treatment resistance will develop.

5 Jun 2021

FDA approves new treatment for patients with hypoplasminogenemia

Today, the U.S. Food and Drug Administration approved Ryplazim (plasminogen, human-tmvh) for the treatment of patients with plasminogen deficiency type 1, also referred to as hypoplasminogenemia, a disorder that can impair normal tissue and organ function and may lead to blindness.

5 Jun 2021

Mason researchers examine the potential anti-coronavirus activities of an over-the-counter drink

Could an over-the-counter health "shot" help fight COVID-19? George Mason University researchers think it just might.

5 Jun 2021

Weight loss drug Wegovy approved by FDA

The U.S. Food and Drug Administration (FDA) has approved Wegovy (semaglutide) injection (2.4 mg once weekly) as a chronic weight management treatment in obese or overweight adults with a weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol), when used along with calorie restriction and physical activity. Wegovy, is a more potent version of Novo Nordisk's diabetes drug semaglutide.

4 Jun 2021

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

The Food and Drug Administration's decision next week whether to approve the first treatment for Alzheimer's disease highlights a deep division over the drug's benefits as well as criticism about the integrity of the FDA approval process.

4 Jun 2021

Methotrexate users fail to achieve adequate immune response to mRNA COVID-19 vaccines

Up to a third of patients taking methotrexate – a common treatment for immune mediated inflammatory conditions such as rheumatoid arthritis and psoriasis/psoriatic arthritis – failed to achieve an adequate immune response to mRNA COVID-19 vaccines in a small study accepted for publication in the journal Annals of the Rheumatic Diseases.

4 Jun 2021

Researchers identify a novel link between aging, metabolism and anti-cancer T-cell function

MUSC Hollings Cancer Center researchers are finding solutions to the aging-related changes that reduce anti-cancer immunity. Besim Ogretmen, Ph.D., and colleagues found a novel link between aging, metabolism and anti-cancer T-cell function. Their work, published in Cell Reports, sheds light on an important pathway that cannot be ignored during cancer treatment.

4 Jun 2021

New technology predicts effectiveness of chemotherapy after one treatment

While early detection of breast cancer is critical, early prediction of how well the neoadjuvant chemotherapy treatment before surgery is working also may provide a window of opportunity when treatment could be altered and have a big impact on the patient's quality of life.

4 Jun 2021

Majority of Republicans support Medicare negotiation on drug prices

A new West Health/Gallup survey finds nearly all Democrats (97%) and the majority of Republicans (61%) support empowering the federal government to negotiate lower prices of brand-name prescription drugs covered by Medicare.

4 Jun 2021

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

A multidisciplinary research team led by Jonathan Lakey, Ph.D., professor of surgery and biomedical engineering at the University of California, Irvine, has developed a biomaterial for pancreatic islet transplants that doesn't trigger the body's immune response.

4 Jun 2021

FDA issues new guidance to improve quality and security of prescription drugs in the U.S. supply chain

The following quote is attributed to Donald D. Ashley, J.D., Director of the Office of Compliance for FDA's Center for Drug Evaluation and Research

4 Jun 2021

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

A preprint paper uploaded to the bioRxiv* server shows how combining drugs targeting different entry factors of the host cell may prevent infection by the virus.

3 Jun 2021

Mast cell activation may underlie inflammation in severe COVID-19

A new preprint research paper posted to the medRxiv* server points to mast cells as major culprits in the etiology of severe and critical COVID-19. This could suggest suitable therapeutic and preventive interventions to reduce the morbidity and mortality of this viral illness.

3 Jun 2021

Study highlights surging trends in prescriptions and costs of antidepressants

Researchers at the University of Huddersfield have warned there is an urgent need for the country's mental health interventions to create strategies optimizing the use of antidepressants after conducting a study which has highlighted an alarming rise in relation to usage and costs.

3 Jun 2021

Immunotherapy after surgery offers recurrence-free survival advantage for patients with high-risk melanoma

Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery.

3 Jun 2021

Research opens alternative therapeutic avenues for treatment of chronic pain

Building on previous findings, scientists have demonstrated that conolidine interacts with the newly identified opioid receptor ACKR3/CXCR7.

3 Jun 2021

KHN’s ‘What the Health?’: The drug price dilemma

The high cost of prescription drugs is among consumers' top health policy issues, according to public opinion polls.

3 Jun 2021

Scientists identify many existing drugs with antiviral activity against coronavirus

Mining the world's most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.

3 Jun 2021

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

3 Jun 2021

Study reveals prevalence of multimorbidity among people using methamphetamine

People who use methamphetamine are more likely to have health conditions, mental illness, and substance use disorders than people who do not use the drug, according to a new study by researchers at the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU School of Global Public Health.

3 Jun 2021

Drugs News and Research

Shorter treatment regimen found to be effective for treating TB

FDA approves new treatment for patients with hypoplasminogenemia

Mason researchers examine the potential anti-coronavirus activities of an over-the-counter drink

Weight loss drug Wegovy approved by FDA

FDA weighs approval of a lucrative Alzheimer’s drug but benefits are iffy

Methotrexate users fail to achieve adequate immune response to mRNA COVID-19 vaccines

Researchers identify a novel link between aging, metabolism and anti-cancer T-cell function

New technology predicts effectiveness of chemotherapy after one treatment

Majority of Republicans support Medicare negotiation on drug prices

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

FDA issues new guidance to improve quality and security of prescription drugs in the U.S. supply chain

Two repurposed drugs inhibit SARS-CoV-2 entry factors in a synergistic manner

Mast cell activation may underlie inflammation in severe COVID-19

Study highlights surging trends in prescriptions and costs of antidepressants

Immunotherapy after surgery offers recurrence-free survival advantage for patients with high-risk melanoma

Research opens alternative therapeutic avenues for treatment of chronic pain

KHN’s ‘What the Health?’: The drug price dilemma

Scientists identify many existing drugs with antiviral activity against coronavirus

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Study reveals prevalence of multimorbidity among people using methamphetamine

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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