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Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed.

22 Nov 2022

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Zika virus (ZIKV) infection is a potentially teratogenic illness, causing up to one in seven infants born to infected mothers to suffer neurodevelopmental deficits. A new study published in the journal Cell shows that some mothers escape injury to their babies because they develop a highly potent neutralizing antibody.

22 Nov 2022

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Scientists at UF Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The

22 Nov 2022

Study shows how HIV protein permanently alters immune cells

Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation.

22 Nov 2022

UVA Health researchers develop new tool to advance genomics and disease research

UVA Health researchers have developed an important new tool to help scientists sort signal from noise as they probe the genetic causes of cancer and other diseases.

22 Nov 2022

Discovery could lead to new mantle cell lymphoma drugs

A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests, according to a study from Weill Cornell Medicine researchers.

22 Nov 2022

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

In a recent study, researchers used proteomic analysis to identify novel immune cell phenotypes associated with severe coronavirus disease 2019 (COVID-19).

22 Nov 2022

Previously unknown links between genetic factors in ASD identified

In a new study published today in Cell Reports, researchers from the Donald K. Johnson Eye Institute (DKJEI), part of the Krembil Research Institute at University Health Network, have identified previously unknown connections between genetic factors in Autism Spectrum Disorder (ASD).

22 Nov 2022

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Researchers mapped spatial, cellular, and molecular interactions of host and tumor-associated bacteria within the tumor microenvironment.

22 Nov 2022

Fujifilm Invests $188 Million in New Cell Culture Media Manufacturing Facility

FUJIFILM Corporation (President and CEO, Representative Director: Teiichi Goto) today announced a $188 million investment to establish a cell culture media manufacturing facility in Research Triangle Park (RTP), North Carolina, USA.

From FUJIFILM Corporation 22 Nov 2022

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

We speak to Matthew Dunne, Director for Drug Discovery at Micreos Pharmaceuticals, about the importance of creating new targeted antibacterial products.

22 Nov 2022

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Researchers explored active and passive vaccination among children against respiratory syncytial virus (RSV).

22 Nov 2022

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

Researchers assessed the effectiveness of SARS-CoV and SARS-CoV-2 envelope proteins against HIV-1.

22 Nov 2022

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

In a recent study published in the journal Advanced Science, researchers developed molecularly imprinted nanoparticles (nanoMIPs) with broad-spectrum activity against lethal viruses.

21 Nov 2022

Scientists provide metrics for organ development

Organs in the human body have complex networks of fluid-filled tubes and loops. They come in different shapes and their three-dimensional structures are differently connected to each other, depending on the organ.

21 Nov 2022

Rice bioengineer receives support for brain cancer research

Kevin McHugh, an assistant professor of bioengineering at Rice University's George R. Brown School of Engineering, has earned a Distinguished Scientist Award for 2022 from The Sontag Foundation, which helps launch the careers of scientists expected to make a significant impact in the fight against brain cancer.

21 Nov 2022

New studies improve understanding of the genetic factors that protect people against COVID-19

Two recent papers by Brazilian researchers have contributed to the scientific understanding of the genetic factors that protect people against infection by SARS-CoV-2 or prevent progression to severe COVID-19.

21 Nov 2022

Using induced pluripotent stem cells to recreate the adrenal gland in a petri dish

Sitting atop the kidneys, the adrenal gland plays a pivotal role in maintaining a healthy body. Responding to signals from the brain, the gland secretes hormones that support critical functions like blood pressure, metabolism, and fertility.

21 Nov 2022

Study finds no benefits from angiotensin receptor blocker treatment for COVID-19

In a recent study published in the BMJ, researchers conducted a phase three, multicenter, randomized controlled trial to evaluate the effect of using angiotensin receptor blockers that disrupt the renin-angiotensin system on the clinical outcomes of individuals with coronavirus disease 2019 (COVID-19).

21 Nov 2022

B Cell News and Research

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Study shows how HIV protein permanently alters immune cells

UVA Health researchers develop new tool to advance genomics and disease research

Discovery could lead to new mantle cell lymphoma drugs

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

Previously unknown links between genetic factors in ASD identified

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Fujifilm Invests $188 Million in New Cell Culture Media Manufacturing Facility

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

Scientists provide metrics for organ development

Rice bioengineer receives support for brain cancer research

New studies improve understanding of the genetic factors that protect people against COVID-19

Using induced pluripotent stem cells to recreate the adrenal gland in a petri dish

Study finds no benefits from angiotensin receptor blocker treatment for COVID-19

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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