Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Calculating protein and gene connections in a Parkinson's model

Researchers have created an algorithm that meshes existing data to produce a clearer step-by-step flow chart of how cells respond to stimuli.

22 Feb 2009

Meningitis bacteria dress up as human cells to evade our immune system

The way in which bacteria that cause bacterial meningitis mimic human cells to evade the body's innate immune system has been revealed by researchers at the University of Oxford and Imperial College London.

20 Feb 2009

Newly discovered mutation can hold the key to treat a large number of different cancers

Scientists have discovered a mutation responsible for cancer progression, a finding with potential implications for the development of treatment against not one, but a series of cancer types since this mutation can be linked to an abnormality recently discovered to exist in all malignancies.

18 Feb 2009

Discovery of metabolite linked to aggressive prostate cancer

Researchers from the University of Michigan Comprehensive Cancer Center have identified a panel of small molecules, or metabolites, that appear to indicate aggressive prostate cancer.

15 Feb 2009

New method to stimulate immune system may be effective at reducing amyloid burden in Alzheimer?s

Researchers at NYU Langone Medical Center have discovered a novel way to stimulate the innate immune system of mice with Alzheimer's disease (AD) - leading to reduced amyloid deposits and the prevention of Alzheimer's disease related pathology - without causing toxic side effects.

15 Feb 2009

Compound can distinguish between benign tissue and localized and metastatic prostate cancer

Researchers have determined that a molecule produced by the bodys metabolism could be used to differentiate between benign prostate tissue vs. localized and metastatic prostate cancer.

11 Feb 2009

Targeted immune cells shrink tumors in mice

Researchers have generated altered immune cells that are able to shrink, and in some cases eradicate, large tumors in mice.

10 Feb 2009

Micro RNA plays a key role in melanoma metastasis

Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly.

9 Feb 2009

New genomic test can personalize breast cancer treatment

A set of 50 genes can be used to reliably identify the four known types of breast cancer, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

9 Feb 2009

Discovery of the novel Fragile X granule could lead to new autism treatment

A Brown University research team has discovered something in the brain that could serve as a target for future autism and mental retardation treatments.

5 Feb 2009

Exposure to second-hand smoke and alcohol significantly raises the risk of liver disease

The finding adds to mounting evidence that tobacco smoke and alcohol are worse for health as a combination, beyond the individual exposure risks, said Shannon Bailey, Ph.D., an associate professor in the UAB Department of Environmental Health Sciences and a co-lead author on the study.

3 Feb 2009

Laparoscopic central pancreatectomy

This minimally invasive procedure, pioneering in Spain, has been developed by a team of surgeons at the University Hospital of Navarra, which brings together the greatest experience worldwide in this technique.

3 Feb 2009

Chronic drinking causes more liver injury than acute or binge drinking

Alcohol consumption is known to cause liver damage. Yet the specifics of alcohol-induced liver injury can differ depending on the pattern of drinking.

3 Feb 2009

Rhythm abnormality of unknown origin strongly predicts sudden death risk in heart disease patients

Researchers conducting a large, ongoing study to improve detection and prevention of sudden cardiac death were surprised to discover that a specific heart rhythm abnormality – idiopathic QT interval prolongation – increased risk five-fold among patients with coronary artery disease.

2 Feb 2009

New potential targets for colitis-associated cancer

Recent research from the laboratory of Michael Karin, PhD, at the University of California, San Diego School of Medicine - the first researcher to demonstrate a molecular link between inflammation and cancer - has identified two potential targets for the prevention and treatment of colitis-associated cancer (CAC), the most serious complication of inflammatory bowel disease.

2 Feb 2009

Rare skin tumor responds better to treatment thanmelanoma

University of Michigan Health System researchers have published new data to help answer two dreaded questions: "Is it cancer?" and "What type of treatment should I have?"

2 Feb 2009

Stress may speed growth of melanoma tumors

For patients with a particularly aggressive form of skin cancer - malignant melanoma - stress, including that which comes from simply hearing that diagnosis, might amplify the progression of their disease.

2 Feb 2009

Researchers identify risk factors for breast cancer in the opposite breast

A preventive procedure to remove the unaffected breast in breast cancer patients with disease in one breast may only be necessary in patients who have high-risk features as assessed by examining the patient's medical history and pathology of the breast cancer, according to researchers at The University of Texas M. D. Anderson Cancer Center.

27 Jan 2009

Researchers identify compound that frees trapped cholesterol

Researchers at UT Southwestern Medical Center have identified in mice a compound that liberates cholesterol that has inappropriately accumulated to excessive levels inside cells.

27 Jan 2009