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Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

A recent study by scientists from Japanese universities has shown that the shape of cell-derived nanoparticles, known as "extracellular vesicles" (EVs), in body fluids could be a biomarker for identifying types of cancer.

7 Jul 2021

Adults with ADHD at higher risk of many physical conditions, finds study

Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry.

7 Jul 2021

Study unravels the link between chromosomal instability and cellular senescence

Chromosomal instability is a feature of solid tumours such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence.

7 Jul 2021

Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy

What if the COVID-19 virus could be used against itself? Researchers at Penn State have designed a proof-of-concept therapeutic that may be able to do just that. The team designed a synthetic defective SARS-CoV-2 virus that is innocuous but interferes with the real virus's growth, potentially causing the extinction of both the disease-causing virus and the synthetic virus.

7 Jul 2021

NYUAD researchers unlock an epigenetic code that allows liver regeneration

NYU Abu Dhabi researchers uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate.

6 Jul 2021

Simple blood tests may help prevent inaccuracy in the diagnosis of severe malaria

Using simple blood tests could help researchers identify children who have been misidentified as having severe malaria, according to a study published today in eLife.

6 Jul 2021

Comprehensive genetic study provides new insights on cleft lip and palate

Cleft lip and palate is one of the most common congenital malformations. Its causes are mainly genetic. However, it is still largely unknown exactly which genes are affected.

6 Jul 2021

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice.

6 Jul 2021

Brain cells snap DNA strands in numerous locations to make memories

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

6 Jul 2021

New method expands view into activity of single cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

6 Jul 2021

Developing a face mask that can detect COVID-19

A face mask has been developed that can detect COVID-19. News-Medical spoke to the researchers behind this idea to find out more about how it works.

6 Jul 2021

Study explores how human ACE2 variants can modify SARS-CoV-2 binding

A recent tour-de-force study by researchers from the United Kingdom reveals variants of the human angiotensin-converting enzyme 2 (ACE2) that can improve or decrease binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – including two variants with distinct population distributions showing an enhanced affinity for viral spike glycoprotein.

5 Jul 2021

Dimeric IgA antibodies help identify recent SARS-CoV-2 infection

A fascinating new study, released as a preprint on the medRxiv* server, adds a highly appealing tool to the armory of detection techniques for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its validation could allow the early and accurate detection of recent or active infection, which is valuable in tracing contacts and preventing forward transmission of the virus.

5 Jul 2021

Researchers develop random priming amplification method for whole-genome sequencing of SARS-CoV-2 and H1N1

Researchers from the UK recently compared the performance of 4 different random priming amplification methods to recover SARS-CoV-2 RNA. In method 1 (H-P), the reverse transcriptase (RT) step included random hexamers, whereas, in methods 2-4, RT incorporated an octamer primer with a known tag. This study is published on the bioRxiv preprint server.

5 Jul 2021

Researchers seek to find a cure for the deadliest solid tumor in children

Australian researchers and oncologists have been awarded $2.4 million to investigate the causes and treatments for neuroblastoma, the deadliest and most common solid tumor in children under the age of five.

5 Jul 2021

New genetic biobank could hold the key to preventing SIDS

A state-of-the-art genetic biobank could hold the key to preventing Sudden Infant Death Syndrome (SIDS), potentially saving the lives of hundreds of babies who die from the devastating condition each year.

5 Jul 2021

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Medical researchers led by Kyushu University have revealed a possible underlying genetic pathway behind the neurological dysfunction of Rett syndrome.

2 Jul 2021

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

Indiana University School of Medicine researchers are developing a new, noninvasive brain stimulation technique to treat neurological disorders, including pain, traumatic brain injury (TBI), epilepsy, Parkinson's disease, Alzheimer's disease and more.

2 Jul 2021

EULAR Patient Research Partners join in new research project to advance treatment of psoriatic arthritis

Eleven Patient Research Partners (PRPs) from three organizations (EULAR, GRAPPA-EU, and EUROPSO) participate in the new research project HIPPOCRATES, ensuring the patients' perspective is preserved and prioritized in all research activities to maximize the project's impact.

2 Jul 2021

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Gaurav Gaiha, MD, DPhil, a member of the Ragon Institute of MGH, MIT and Harvard, studies HIV, one of the fastest-mutating viruses known to humankind.

2 Jul 2021

Genetic News and Research

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

Adults with ADHD at higher risk of many physical conditions, finds study

Study unravels the link between chromosomal instability and cellular senescence

Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy

NYUAD researchers unlock an epigenetic code that allows liver regeneration

Simple blood tests may help prevent inaccuracy in the diagnosis of severe malaria

Comprehensive genetic study provides new insights on cleft lip and palate

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Brain cells snap DNA strands in numerous locations to make memories

New method expands view into activity of single cells

Developing a face mask that can detect COVID-19

Study explores how human ACE2 variants can modify SARS-CoV-2 binding

Dimeric IgA antibodies help identify recent SARS-CoV-2 infection

Researchers develop random priming amplification method for whole-genome sequencing of SARS-CoV-2 and H1N1

Researchers seek to find a cure for the deadliest solid tumor in children

New genetic biobank could hold the key to preventing SIDS

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

EULAR Patient Research Partners join in new research project to advance treatment of psoriatic arthritis

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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