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Study identifies certain small molecule chemicals that can disrupt quorum sensing in A. baumanni

Acinetobacter baumanni, a pathogenic bacterium that is a poster child of deadly hospital acquired infections, is one tough customer.

22 Aug 2012

Study highlights Nek9 protein as decisive factor in cell division

A study by the Institute for Research in Biomedicine (IRB Barcelona) and the Center for Genomic Regulation (acronym in Catalan CRG) highlights the protein Nek9 as a decisive factor in cell division, a fundamental process for both the development of an organism and tissue maintenance.

22 Aug 2012

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

The MitoTarget Project was a project funded by the European Commission, under their FP7 programme. It was funding for a call published in 2007.

21 Aug 2012

Thiabendazole drug slows tumor growth and shows promise as chemotherapy for cancer

An inexpensive antifungal drug, thiabendazole, slows tumor growth and shows promise as a chemotherapy for cancer. Scientists in the College of Natural Sciences at The University of Texas at Austin made this discovery by exploiting the evolutionary relatedness of yeast, frogs, mice and humans.

21 Aug 2012

Semen protein acts on the female brain to prompt ovulation

An international team of scientists led by Gregg Adams at the University of Saskatchewan has discovered that a protein in semen acts on the female brain to prompt ovulation, and is the same molecule that regulates the growth, maintenance, and survival of nerve cells.

21 Aug 2012

PPR proteins recognise RNA targets via easy-to-understand code

The code determines the recognition of RNA molecules by a superfamily of RNA-binding proteins called pentatricopeptide repeat (PPR) proteins.

20 Aug 2012

Resveratrol might help improve mobility and prevent life-threatening falls among older people

In a stride toward better health in later life, scientists reported today that resveratrol, the so-called "miracle molecule" found in red wine, might help improve mobility and prevent life-threatening falls among older people.

20 Aug 2012

Peptide combinations might offer more effective cancer therapy

Two studies suggest that two peptide agents used either together or individually with a low-dose of a standard chemotherapy drug might offer more effective cancer therapy than current standard single-drug treatments.

17 Aug 2012

Researchers use small molecule compound to generate reversible birth control in male mice

The development of a male contraceptive pill has long proven to be elusive, but findings from a new study may point scientists in the right direction to making oral birth control for men a reality.

17 Aug 2012

Rhomboid enzymes and malaria treatment: an interview with Sinisa Urban

Rhomboid enzymes live in the cell’s membrane where their job is to cut the anchors of proteins, which releases the target proteins from the membrane.

16 Aug 2012

Passenger deletions that deactivate essential genes provide new opportunity to strike cancer

Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vulnerabilities and new avenues for attack.

16 Aug 2012

Brain changes can occur after long-term methadone treatment

Long-term methadone treatment can cause changes in the brain, according to recent studies from the Norwegian Institute of Public Health. The results show that treatment may affect the nerve cells in the brain. The studies follow on from previous studies where methadone was seen to affect cognitive functioning, such as learning and memory.

16 Aug 2012

Diffusion Pharmaceuticals receives new U.S. patents for trans sodium crocetinate

Diffusion Pharmaceuticals LLC, a biotechnology company focused on innovative cancer treatments, today announced that the U.S. Patent and Trademark Office has granted it patent numbers 7919527 and 8030350, entitled "Bipolar Trans Carotenoids Salts and Their Uses" and "Trans Carotenoids, Their Synthesis and Uses," respectively.

16 Aug 2012

Scientists reveal how TREX proteins act as passport for transfer of cell blueprints

Decoded process could hold the key to future treatments for a wide range of chronic health problems including Motor Neuron Disease, myotonic dystrophy and a wide range of cancers, University of Sheffield scientists have revealed.

16 Aug 2012

Rice University researcher to see how delays in gene transcription affect cellular processes

A Rice University researcher and his colleagues have received a National Institutes of Health grant to see how delays in gene transcription - life's most basic messaging system - affect cellular processes.

16 Aug 2012

TG2 plays a key role in serotonin deficiency associated with depression

Connecting the dots between two molecules whose levels are decreased in depression and increased by current antidepressants could yield new therapies, researchers say.

15 Aug 2012

CD4 T cells orchestrate inflammatory attack on the artery wall

Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system.

15 Aug 2012

Glioblastoma patients with modified PTEN have resistance to EGFR inhibitors

Despite years of research, glioblastoma, the most common and deadly brain cancer in adults, continues to outsmart treatments targeted to inhibit tumor growth.

15 Aug 2012

Antisense therapy shows promise in treating toxoplasmosis

A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, it reduced the number of viable parasites by more than 90 percent, researchers from the University of Chicago Medicine report in the Proceedings of the National Academy of Sciences.

14 Aug 2012

Targeting elevated HLX gene expression may treat acute myeloid leukemia

Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a rare and usually fatal cancer, are a step closer to new treatment options. Their study results were published online today in Cancer Cell.

14 Aug 2012

Molecule News and Research

Study identifies certain small molecule chemicals that can disrupt quorum sensing in A. baumanni

Study highlights Nek9 protein as decisive factor in cell division

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

Thiabendazole drug slows tumor growth and shows promise as chemotherapy for cancer

Semen protein acts on the female brain to prompt ovulation

PPR proteins recognise RNA targets via easy-to-understand code

Resveratrol might help improve mobility and prevent life-threatening falls among older people

Peptide combinations might offer more effective cancer therapy

Researchers use small molecule compound to generate reversible birth control in male mice

Rhomboid enzymes and malaria treatment: an interview with Sinisa Urban

Passenger deletions that deactivate essential genes provide new opportunity to strike cancer

Brain changes can occur after long-term methadone treatment

Diffusion Pharmaceuticals receives new U.S. patents for trans sodium crocetinate

Scientists reveal how TREX proteins act as passport for transfer of cell blueprints

Rice University researcher to see how delays in gene transcription affect cellular processes

TG2 plays a key role in serotonin deficiency associated with depression

CD4 T cells orchestrate inflammatory attack on the artery wall

Glioblastoma patients with modified PTEN have resistance to EGFR inhibitors

Antisense therapy shows promise in treating toxoplasmosis

Targeting elevated HLX gene expression may treat acute myeloid leukemia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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