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New drug could be a game changer for cancer patients undergoing chemotherapy

Cisplatin is a chemotherapy indicated to fight tumors in many types of cancer. However, it does have major side effects – especially kidney toxicity, that can lead to acute kidney failure.

15 Nov 2022

Gene may play a broader role in embryonic organ development

An international study led by the medical Faculty of the University of Bonn has identified a gene that plays an important role in the development of the human embryo. If it is altered, malformations of various organ systems can result.

15 Nov 2022

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

15 Nov 2022

Research sheds light on cardiac pathology mechanisms of COVID-19

Researchers compared cardiac autopsy samples from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive cases with age-matched samples from influenza hemagglutinin 1 neuraminidase 1 (H1N1) cases, non-influenza lymphocytic myocarditis cases, and heart tissue with no inflammation to understand the mechanisms underlying the pathology of the cardiac complications during coronavirus disease 2019 (COVID-19).

15 Nov 2022

Unique cellular signature can accurately detect obstructive sleep apnea in children

Researchers from the University of Missouri School of Medicine have discovered how obstructive sleep apnea (OSA) changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately detect obstructive sleep apnea in children.

15 Nov 2022

Utilizing marine sources to extract DHA to treat Alzheimer’s

The anti-neurodegenerative effects of docosahexaenoic acid (DHA) and DHA-rich phospholipids (DH-PL) derived from fisheries and aquaculture byproducts.

15 Nov 2022

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Researchers discuss the beneficial role of polyphenolic plant compounds in the Mediterranean diet in the prevention and treatment of COVID-19.

15 Nov 2022

What are the current challenges and future directions of mRNA nanomedicine?

Researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations and future directions to improve the clinical efficacy of mRNA nanomedicine.

15 Nov 2022

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified 35 genes that are particularly highly expressed in people with long-term Lyme disease.

15 Nov 2022

Parasites associated with leprosy may have the ability to regenerate livers

Leprosy is one of the world's oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ.

15 Nov 2022

Carnitine intake in the first postnatal weeks promotes better growth, larger brain size in very preterm infants

A recent study by the University of Eastern Finland and Kuopio University Hospital shows that carnitine intake in the first postnatal weeks promotes better growth and larger brain size at term equivalent age in very preterm infants.

15 Nov 2022

Minimally invasive reporter system allows highly sensitive monitoring of RNA production

The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed.

15 Nov 2022

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

During the conference, we caught up with some of the speakers to learn more about their work, what they were presenting, and their thoughts about the future of Oncology and Precision Medicine.

15 Nov 2022

What is the association between diabetes and SARS-CoV-2 infections?

Researchers explored whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can expedite or trigger the development of diabetes mellitus (DM).

15 Nov 2022

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Researchers proposed that vaccines targeting the immunosubdominant yet conserved hemagglutinin (HA) stem could trigger broadly neutralizing antibodies (bnAbs) against influenza A viruses.

15 Nov 2022

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

Researchers used a high throughput systems serology method to compare serum and CSF samples from SARS-CoV-2 infected individuals with and without long COVID symptoms to determine changes in the SARS-CoV-2 humoral immune responses.

15 Nov 2022

The origin of COVID-19: wildlife trade rather than laboratory leak?

A recent opinion piece published in PNAS discussed the sequence of events concerning the COVID-19 pandemic to provide evidence against the alleged leak of SARS-CoV-2 and the Ebola virus from viral research laboratories in Wuhan, China, and West Africa, respectively.

15 Nov 2022

The impact of lung remodeling from prior helminth infection on SARS-CoV-2 disease pathogenesis

A recent study reported that helminth exposure enhances viral clearance and survival of mice challenged with SARS-CoV-2.

15 Nov 2022

A novel mRNA-based vaccine candidate against the rabies virus

Scientists have developed a novel mRNA-based vaccine candidate against the rabies virus. The vaccine induces a strong antibody response and exhibits high protective efficacy against lethal rabies infection in mice and dogs. A full report about the vaccine has been published in the Virology Journal.

14 Nov 2022

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions - such as cell types or tissues.

14 Nov 2022

B Cell News and Research

New drug could be a game changer for cancer patients undergoing chemotherapy

Gene may play a broader role in embryonic organ development

Error-prone DNA replication and repair may lead to cancer in people with inherited BRCA1 mutations

Research sheds light on cardiac pathology mechanisms of COVID-19

Unique cellular signature can accurately detect obstructive sleep apnea in children

Utilizing marine sources to extract DHA to treat Alzheimer’s

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

What are the current challenges and future directions of mRNA nanomedicine?

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Parasites associated with leprosy may have the ability to regenerate livers

Carnitine intake in the first postnatal weeks promotes better growth, larger brain size in very preterm infants

Minimally invasive reporter system allows highly sensitive monitoring of RNA production

Behind the Scenes of the Oncology & Precision Medicine Conferences 2022

What is the association between diabetes and SARS-CoV-2 infections?

Hemagglutinin stem immunogens may hold the key for broad protection against influenza A viruses

Study points to a pathogenic role for compromised anti-SARS-CoV-2 responses in cerebrospinal fluid

The origin of COVID-19: wildlife trade rather than laboratory leak?

The impact of lung remodeling from prior helminth infection on SARS-CoV-2 disease pathogenesis

A novel mRNA-based vaccine candidate against the rabies virus

CLIMB method offers a more efficient way to uncover biologically meaningful changes in genomic data

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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