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Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

In a recent study posted to the medRxiv* preprint server, researchers in Canada evaluated nirmatrelvir and ritonavir (Paxlovid) effectiveness against severe coronavirus disease 2019 (COVID-19) during the dominance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and Omicron sub-VOCs in Canada.

7 Nov 2022

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Ramping up medication doses quickly after being hospitalized for acute heart failure resulted in a lower risk of dying or being readmitted for heart failure within the first six months after discharge, compared to usual care, according to a featured science research presentation today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Microscopic IBD inflammation linked to women's elevated risk of giving birth preterm

Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a University of Gothenburg study shows.

7 Nov 2022

Paxlovid antiviral therapy reduces risk of long COVID

In a recent study posted to the medRxiv* server, researchers in Saint Louis, Missouri, examined whether nirmatrelvir treatment reduced the risk of long COVID, the disease encompassing the post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [PASC].

7 Nov 2022

UC San Diego Health earns The Joint Commission’s Gold Seal of Approval for Advanced Certification in Spine Surgery

UC San Diego Health has earned The Joint Commission's Gold Seal of Approval for Advanced Certification in Spine Surgery by meeting or exceeding the highest level of national performance standards.

7 Nov 2022

Crowded emergency departments linked with higher rates of death throughout the hospital

Prior research has established that crowding in emergency departments can lead to worse outcomes for patients receiving emergency care.

7 Nov 2022

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

Performing open bypass surgery to restore circulation for people with a severe form of peripheral artery disease (PAD) – a condition that limits blood flow to the legs and feet – resulted in better outcomes for specific patients compared to a less-invasive procedure, a National Institutes of Health-supported clinical research trial has found.

7 Nov 2022

Exercise program improves insulin action in the brain

If the brain no longer responds correctly to the hormone insulin (insulin resistance), this also has a negative effect on the metabolism in the body and the regulation of eating behavior.

7 Nov 2022

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

A genetic test known as chromosomal microarray analysis (CMA) could help identify the cause of sudden infant death syndrome (SIDS) or its counterpart in older children, known as sudden unexplained death in childhood (SUDC), finds a study led by Boston Children's Hospital.

7 Nov 2022

Psilocybin could be a promising therapeutic strategy for people with treatment-resistant depression

Researchers at Trinity College Dublin have participated in the largest and most rigorous clinical trial to date of psilocybin (a psychoactive ingredient in magic mushrooms), pointing to the possibility that COMP360 psilocybin with psychological support could be a beneficial therapeutic strategy for people with treatment-resistant depression (TRD).

7 Nov 2022

Personalized whole genome sequencing approach could double the diagnostic rates of rare diseases

Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers.

7 Nov 2022

Pioneering artificial intelligence could ease winter pressures on hospitals

Pioneering artificial intelligence (AI) which automatically diagnoses lung diseases – such as tuberculosis and pneumonia – could ease winter pressures on hospitals, University of the West of Scotland researchers believe.

7 Nov 2022

Evaluating dual direct-acting antivirals against persistent COVID-19

Researchers assessed the efficiency of dual direct-acting antivirals in treating persistent coronavirus disease 2019 (COVID-19).

7 Nov 2022

Supreme Court to hear nursing home case that could affect millions

When Susie Talevski sued the agency that managed her elderly father's care before he died, she hoped to get justice for her family.

7 Nov 2022

Study suggests anti-PF4 antibodies may play a role in the severe multiorgan disease manifestations of COVID-19

Researchers investigated the association between the increased levels of anti-platelet factor 4 antibodies and the clinical complications of COVID-19.

7 Nov 2022

Study shows likely SARS-CoV-2 transmission between different rooms of a quarantine hotel

The results of this study, published in the Emerging Infectious Diseases journal, underline the enhanced transmissibility of the Omicron variants of the virus, which takes advantage of small airstreams to jump to new hosts. "Our findings emphasize the importance of ventilation and integrity of building structure in quarantine facilities."

6 Nov 2022

Study examines temporal effects of pre-existing CKD, other medical conditions on COVID-19 outcomes

Individuals with chronic kidney disease (CKD) are vulnerable to developing severe forms of COVID-19, and acute kidney injury is a common complication of COVID-19.

6 Nov 2022

Novel drug lowers triglycerides, does not reduce cardiovascular events

Levels of triglycerides are routinely measured as part of a preventive cardiology work-up and lowering triglycerides with several classes of drugs is common medical practice.

6 Nov 2022

MicroRNA can be used as a biomarker to predict breast cancer recurrence and mortality, study says

MicroRNA (miRNA) can be used as a biomarker to predict which patients are likely to face breast cancer recurrence and mortality, according to study results published online ahead of print in the Journal of the American College of Surgeons.

6 Nov 2022

$Hypofractionated radiotherapy for patients with soft tissue sarcomas can be a safe, effective alternative to standard of care$

Hypofractionated radiotherapy for patients with soft tissue sarcomas can be a safe, effective alternative to standard of care

Patients with non-metastatic soft tissue sarcoma (STS) who need pre-operative radiation therapy can safely receive hypofractionated treatment over three weeks instead of five, with comparable tumor control and no increased risk of major complications in wound healing, according to researchers at The University of Texas MD Anderson Cancer Center.

6 Nov 2022

Hospital News and Research

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Microscopic IBD inflammation linked to women's elevated risk of giving birth preterm

Paxlovid antiviral therapy reduces risk of long COVID

UC San Diego Health earns The Joint Commission’s Gold Seal of Approval for Advanced Certification in Spine Surgery

Crowded emergency departments linked with higher rates of death throughout the hospital

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

Exercise program improves insulin action in the brain

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

Psilocybin could be a promising therapeutic strategy for people with treatment-resistant depression

Personalized whole genome sequencing approach could double the diagnostic rates of rare diseases

Pioneering artificial intelligence could ease winter pressures on hospitals

Evaluating dual direct-acting antivirals against persistent COVID-19

Supreme Court to hear nursing home case that could affect millions

Study suggests anti-PF4 antibodies may play a role in the severe multiorgan disease manifestations of COVID-19

Study shows likely SARS-CoV-2 transmission between different rooms of a quarantine hotel

Study examines temporal effects of pre-existing CKD, other medical conditions on COVID-19 outcomes

Novel drug lowers triglycerides, does not reduce cardiovascular events

MicroRNA can be used as a biomarker to predict breast cancer recurrence and mortality, study says

Hypofractionated radiotherapy for patients with soft tissue sarcomas can be a safe, effective alternative to standard of care

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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