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Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.

24 Jul 2019

Exosomes can restore health to brain cells affected by developmental disease

Like overpacked suitcases unloaded from the underbelly of a jet, molecular satchels called exosomes are continuously deployed from all cells in the body—each one brimming with an assortment of contents that another cell may unpack and use.

23 Jul 2019

New drug-delivery system disguises chemotherapeutics as fat to outsmart tumors

A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors.

18 Jul 2019

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

Researchers at Boston Children's Hospital report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in a dish, and then suppressing the arrhythmia with gene therapy in a mouse model.

17 Jul 2019

Study reveals first complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism.

4 Jul 2019

Scientists identify mechanism that makes babies more likely than adults to die from sepsis

An immune mechanism that makes babies more likely than adults to die from sepsis has been identified by scientists affiliated with the Center for Research on Inflammatory Diseases in Ribeirão Preto, São Paulo State (Brazil).

4 Jul 2019

Scientists discover new way to direct stem cells to heart tissue

In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK.

4 Jul 2019

New target identified for treatment of idiopathic pulmonary fibrosis

An article published in Experimental Biology and Medicine (Volume 244, Issue 9, June 2019) (https://journals.sagepub.com/doi/pdf/10.1177/1535370219843827) identifies a new target for the treatment of idiopathic pulmonary fibrosis.

29 Jun 2019

UCLA researcher looks for ways to detect ovarian cancer before it develops

Out of the 22,240 women in the United States who are diagnosed with ovarian cancer every year, only about 47 percent survive longer than five years.

28 Jun 2019

Cascade aggravates hereditary storage diseases

In rare, hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing.

26 Jun 2019

UAB scientists identify new target for drug intervention in Alzheimer's disease

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer's disease and other dementias.

26 Jun 2019

Study shows how gastric stem cells fight colonizing bacteria

Stem cells are not only key players in tissue regeneration, they are also capable of taking direct action against bacteria.

25 Jun 2019

Injectable hydrogel offers double punch against bone infections

Surgery prompted by automobile accidents, combat wounds, cancer treatment and other conditions can lead to bone infections that are difficult to treat and can delay healing until they are resolved.

25 Jun 2019

Introduction of very small RNA molecule promotes heart cell regeneration, study shows

By adulthood, the heart is no longer able to replenish injured or diseased cells. As a result, heart disease or an event like a heart attack can be disastrous, leading to massive cell death and permanent declines in function.

23 Jun 2019

New swine model helps scientists to better understand human brain

For the first time, researchers in the University of Georgia's Regenerative Bioscience Center have used an imaging method normally reserved for humans to analyze brain activity in live agricultural swine models, and they have discovered that pig brains are even better platforms than previously thought for the study of human neurological conditions such as Alzheimer's and Parkinson's.

21 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

Animal Model News and Research

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Exosomes can restore health to brain cells affected by developmental disease

New drug-delivery system disguises chemotherapeutics as fat to outsmart tumors

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

Study reveals first complete wiring diagram of an animal's nervous system

Scientists identify mechanism that makes babies more likely than adults to die from sepsis

Scientists discover new way to direct stem cells to heart tissue

New target identified for treatment of idiopathic pulmonary fibrosis

UCLA researcher looks for ways to detect ovarian cancer before it develops

Cascade aggravates hereditary storage diseases

UAB scientists identify new target for drug intervention in Alzheimer's disease

Study shows how gastric stem cells fight colonizing bacteria

Injectable hydrogel offers double punch against bone infections

Introduction of very small RNA molecule promotes heart cell regeneration, study shows

New swine model helps scientists to better understand human brain

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Novel approach of blocking inflammation before surgical procedure may prevent cancer recurrences

Research paves way for new treatment to protect people from cardiovascular disease

New therapeutic strategy treats viral infection and boosts immunity against cancer

Doctoral thesis focuses on the role of oxidative stress in Wolfram syndrome and hypothermia

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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