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Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Jumping gene plays an important role in reducing depression, fear, and anxiety

First characterized in Prof. Tadashi Yamamoto's former lab in Japan in 1996, the gene Tob is well known for the role it plays in cancer. Previous research has also indicated that it has a hand in regulating the cell cycle and the body's immune response.

9 Sep 2022

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

9 Sep 2022

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type, pancreatic ductal adenocarcinoma (PDAC), is growing and projected to be the second cause of cancer deaths by 2030.

8 Sep 2022

Stem cell-derived liver cell model could be a valuable tool for future studies on Ebola virus

Ebola virus causes serious infections in humans and in fatal cases, damage and dysfunction of the liver is often present, suggesting that the liver plays a decisive role in disease outcome.

8 Sep 2022

Donor iron deficiency produces no harmful effects on donated blood quality or donor wellbeing

Most of the U.S. blood supply comes from about 5 million altruistic volunteers who donate blood regularly. Frequent blood donation is known to result in iron deficiency in donors, which has led to concerns that the practice may not only diminish the quality of donated blood but also harm blood donors' health and quality of life.

8 Sep 2022

Pitt researchers describe a pathway by which cells repair damaged lysosomes

Today in Nature, University of Pittsburgh researchers describe for the first time a pathway by which cells repair damaged lysosomes, structures that contribute to longevity by recycling cellular trash.

8 Sep 2022

Lactate may have a previously unrecognized role in fighting cancer

A new study by UT Southwestern's Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer.

6 Sep 2022

Omicron BA.2.75 not more resistant to antibodies than the currently dominating BA.5 variant, study suggests

In a recent study, researchers from Karolinska Institutet in Sweden, and others, have characterised the new omicron variant BA.2.75, comparing its ability to evade antibodies against current and previous variants.

2 Sep 2022

Men with low testosterone may have higher risk of COVID-19 hospitalization

Men with low testosterone who develop COVID-19 are at elevated risk of becoming seriously ill and ending up in the hospital, according to a study by researchers at Washington University School of Medicine in St. Louis and Saint Louis University School of Medicine.

2 Sep 2022

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

Cell Counting Without Slides to Reduce Waste and Cost

Until recently, cells were typically counted on a reusable quartz hemocytometer.

From DeNovix Inc. 1 Sep 2022

Popular genetic method is deeply flawed, study reveals

The most common analytical method within population genetics is deeply flawed, according to a new study from Lund University in Sweden.

30 Aug 2022

Study reveals a vital route through which fascin promotes cancer development

The study reveals an important route through which fascin promotes cancer development and provides insights into potential pathways that could block its action.

30 Aug 2022

New treatment may be effective in addressing the long-term effects of preeclampsia

Preeclampsia is a condition that affects the placenta during pregnancy and is dangerous for both the fetus and the mother.

30 Aug 2022

Using the power of CRISPR to engineer better, stronger, longer-lived T cells

T cells used in immunotherapy treatments can get exhausted by the task of fighting cancer cells or get shutdown as they enter tumors.

24 Aug 2022

Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine.

24 Aug 2022

Non-nutritive sweeteners cause changes in the gut microbes and impact glucose tolerance

Since the late 1800s non-nutritive sweeteners have promised to deliver all the sweetness of sugar with none of the calories.

19 Aug 2022

New discovery helps explain the dynamics underlying liver damage in type 2 diabetes and obesity

When fat accumulates in the liver, the immune system may assault the organ. A new study from Weill Cornell Medicine researchers identifies the molecule that trips these defenses, a discovery that helps to explain the dynamics underlying liver damage that can accompany type 2 diabetes and obesity.

19 Aug 2022

Increasing the production of new neurons rescues memory defects in mice with Alzheimer's disease

Researchers at the University of Illinois Chicago have discovered that increasing the production of new neurons in mice with Alzheimer's disease (AD) rescues the animals' memory defects.

19 Aug 2022

Cell Biology News and Research

Blocking FNDC5 prevents cancer-induced cachexia in mice

Jumping gene plays an important role in reducing depression, fear, and anxiety

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

Stem cell-derived liver cell model could be a valuable tool for future studies on Ebola virus

Donor iron deficiency produces no harmful effects on donated blood quality or donor wellbeing

Pitt researchers describe a pathway by which cells repair damaged lysosomes

Lactate may have a previously unrecognized role in fighting cancer

Omicron BA.2.75 not more resistant to antibodies than the currently dominating BA.5 variant, study suggests

Men with low testosterone may have higher risk of COVID-19 hospitalization

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Cell Counting Without Slides to Reduce Waste and Cost

Popular genetic method is deeply flawed, study reveals

Study reveals a vital route through which fascin promotes cancer development

New treatment may be effective in addressing the long-term effects of preeclampsia

Using the power of CRISPR to engineer better, stronger, longer-lived T cells

Optimized human small intestinal organoids can help better study the functioning of small intestines

Non-nutritive sweeteners cause changes in the gut microbes and impact glucose tolerance

New discovery helps explain the dynamics underlying liver damage in type 2 diabetes and obesity

Increasing the production of new neurons rescues memory defects in mice with Alzheimer's disease

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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