Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Study identifies risk factors for cardiotoxicity with relapsed multiple myeloma therapy

More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12 in Journal of Clinical Oncology.

14 Jun 2019

More screening and new treatments needed for sickle cell disease

The promise of new treatments for sickle cell disease, a group of inherited red blood cell disorders, has never been so great, but it will only be realized if there is constant investment in health policies such as programs for screening newborns, especially in sub-Saharan Africa, where most cases occur.

13 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Today, the U.S. Food and Drug Administration granted accelerated approval to Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy bendamustine and a rituximab product (a combination known as "BR"), to treat adult patients with diffuse large B-cell lymphoma (DLBCL) that has progressed or returned after at least two prior therapies.

10 Jun 2019

Tart cherry reduces joint pain and sore muscles in some breast cancer patients, study shows

Tart cherry reduces the musculoskeletal effects of aromatase inhibitors in patients with non-metastatic breast cancer, according to new findings from a clinical trial by researchers at Marshall University Joan C. Edwards School of Medicine and Edwards Comprehensive Cancer Center.

10 Jun 2019

HORIBA Medical announces first multi-site installation of HELO modular automated hematology platform

HORIBA UK Ltd, Medical announces the go live of the first multi-site installation of its new HELO high throughput fully automated hematology platform within the Cardiff and Vale University Health Board.

From HORIBA Scientific UK 31 May 2019

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells.

28 May 2019

Pediatric cancer patients wait an average of 6.5 years longer than adults to access new drugs

Cancer drugs approved by the U.S. Food and Drug Administration took a median of 6.5 years to go from the first clinical trial in adults to the first trial in children, according to a study at the Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

22 May 2019

Routine screening for SCD among refugees could help prevent life-threatening complications

Hematologists are zeroing in on the escalating humanitarian crisis in southern Europe by assessing the burden of blood disorders among refugees and identifying strategies to facilitate more timely identification and treatment of refugees with sickle cell disease.

9 May 2019

New blood-cell analysis device helps better understand causes and mechanics of rare anemia

An EU-funded project has developed a blood-cell analysis device that helps doctors and scientists better understand the causes and mechanics of rare forms of anemia - potentially speeding up the development of new treatments adjusted to the needs of patients with these diseases.

25 Apr 2019

Using blood thinners in heart failure patients associated with reduced risk of thromboembolic events

Researchers at University of California San Diego School of Medicine found that using blood thinners in patients with worsening heart failure, coronary artery disease or irregular heart rhythms was associated with a 17 percent reduced risk of thromboembolic events, such as stroke and heart attack.

25 Apr 2019

DNA rearrangement may predict poor outcomes in multiple myeloma

A certain type of DNA marker predicts poor outcomes in multiple myeloma, researchers at Winship Cancer Institute, Emory University have found.

24 Apr 2019

Research sheds light on how leukemia cells become resistant to drugs

Three children Alejandro Gutierrez, MD, treated for leukemia during his fellowship at Boston Children's Hospital still haunt him more than a decade later.

17 Apr 2019

Coagulation factor VIIa prevents bleeds in hemophilia animal models

Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well.

16 Apr 2019

FDA approves new treatment for adults with metastatic bladder cancer

The U.S. Food and Drug Administration today granted accelerated approval to Balversa (erdafitinib), a treatment for adult patients with locally advanced or metastatic bladder cancer that has a type of susceptible genetic alteration known as FGFR3 or FGFR2, and that has progressed during or following prior platinum-containing chemotherapy.

12 Apr 2019

Cancer patients and those with anemia should not be denied opioids, says CDC

The U.S. CDC has issued a letter clarifying that people suffering from severe pain caused by cancer or sickle-cell anemia should not be denied prescriptions for opioid pain-killers.

11 Apr 2019

Human iPSCs-derived mesenchymal stem cells could avoid ageing-related shortfalls

The use of primary mesenchymal stem cells is fraught with ageing-related shortfalls such as limited expansion and early senescence.

11 Apr 2019

Study offers novel insights into how a major tumor suppressor pathway becomes deactivated

The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans.

5 Apr 2019

FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

Study reveals investigational drug as effective treatment for relapsed marginal zone lymphoma

A study at The University of Texas MD Anderson Cancer Center revealed the investigational drug umbralisib as an effective treatment for patients with relapsed marginal zone lymphoma.

1 Apr 2019

Hematology News and Research

Further Reading

Study identifies risk factors for cardiotoxicity with relapsed multiple myeloma therapy

More screening and new treatments needed for sickle cell disease

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

First chemoimmunotherapy regimen approved by FDA for patients with diffuse large B-cell lymphoma

Tart cherry reduces joint pain and sore muscles in some breast cancer patients, study shows

HORIBA Medical announces first multi-site installation of HELO modular automated hematology platform

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Pediatric cancer patients wait an average of 6.5 years longer than adults to access new drugs

Routine screening for SCD among refugees could help prevent life-threatening complications

New blood-cell analysis device helps better understand causes and mechanics of rare anemia

Using blood thinners in heart failure patients associated with reduced risk of thromboembolic events

DNA rearrangement may predict poor outcomes in multiple myeloma

Research sheds light on how leukemia cells become resistant to drugs

Coagulation factor VIIa prevents bleeds in hemophilia animal models

FDA approves new treatment for adults with metastatic bladder cancer

Cancer patients and those with anemia should not be denied opioids, says CDC

Human iPSCs-derived mesenchymal stem cells could avoid ageing-related shortfalls

Study offers novel insights into how a major tumor suppressor pathway becomes deactivated

FDA extends indication of metastatic breast cancer treatment to include male patients

Study reveals investigational drug as effective treatment for relapsed marginal zone lymphoma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo