Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Study: Alginate-enriched bread can reduce fat digestion, circulatory lipids in NAFLD patients

A study revealed today at The International Liver Congress 2015 has demonstrated that alginate-enriched bread has the potential to inhibit fat digestion and circulatory lipids in patients with non-alcoholic fatty liver disease (NAFLD).

23 Apr 2015

May issues of AGA's journals highlight important research updates on liver disease

The May issues of AGA's journals -- Clinical Gastroenterology and Hepatology and Gastroenterology -- highlight important research updates on the most deadly forms of liver disease.

23 Apr 2015

New educational resource to help improve knowledge, treatment of Inflammatory Bowel Disease

A new educational resource for doctors and healthcare professionals will help improve knowledge and treatment of Inflammatory Bowel Disease (IBD). The Inflammatory Bowel Disease Resource Centre was developed by Elsevier, the journal Digestive and Liver Disease, and was made possible through an educational grant from Ferring Pharmaceuticals.

22 Apr 2015

Study calls for effective strategies to contain potential HDV epidemic in high-risk populations

Researchers from Taiwan determined that individuals with human immunodeficiency virus (HIV) infection or those who inject illicit drugs have a higher risk of becoming infected with the hepatitis D virus (HDV) in that country.

22 Apr 2015

Study reveals new target for research into liver disease

In a recent study, Virginia Commonwealth University School of Medicine researchers predicted which cirrhosis patients would suffer inflammations and require hospitalization by analyzing their saliva, revealing a new target for research into a disease that accounts for more than 30,000 deaths in the United States each year.

20 Apr 2015

No effect of baseline cirrhosis on long-term TDF treatment outcomes

Research suggests that virological, serological and histological outcomes are comparable between cirrhotic and noncirrhotic patients with chronic hepatitis B virus infection undergoing long-term tenofovir disoproxil fumarate treatment.

13 Apr 2015

Study: Standard nursing assessments may help improve outcomes in cirrhosis patients

Patients hospitalized with advanced cirrhosis, a chronic and degenerative disease of the liver, are at increased risk of death. The tools currently used to assess that risk are limited in predicting which patients will need a liver transplant and which will be healthy enough to survive transplantation.

8 Apr 2015

New simeprevir clinical data to be presented at EASL's International Liver Congress 2015

Janssen Sciences Ireland UC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, today announced that clinical data for simeprevir, its NS3/4A protease inhibitor for the treatment of hepatitis C virus (HCV) infection, will be presented at The International Liver Congress 2015 of the European Association for the Study of the Liver taking place in Vienna from April 22-26.

8 Apr 2015

Exercise benefits obese, overweight people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of frequency or intensity, benefits obese and overweight adults with NAFLD.

8 Apr 2015

NASH patients more likely to have increased intestinal permeability, shows study

Non-alcoholic steatohepatitis (NASH), the more severe form of non-alcoholic fatty liver disease (NAFLD) that can progress to liver fibrosis and cirrhosis, is associated with leakiness of the intestinal wall, which in turn may worsen liver disease, according to research published in Cellular and Molecular Gastroenterology and Hepatology, the new basic science journal of the American Gastroenterological Association.

3 Apr 2015

Women with IBD may be at increased risk for developing cervical cancer

Women with inflammatory bowel disease (IBD) may be at increased risk of cervical dysplasia and cancer, according to a new study1 published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

27 Mar 2015

FDA approves CHOLBAM (cholic acid) for treatment of bile acid synthesis disorders

Asklepion Pharmaceuticals, LLC. today announced that the U.S. Food and Drug Administration (FDA) approved CHOLBAM (cholic acid) as a once-daily treatment for cholic acid deficiency in bile acid synthesis disorders due to single enzyme defects.

18 Mar 2015

New hepatitis C drugs to place economic burden on health care system, predicts MD Anderson study

The cost of treating people infected with the hepatitis C virus (HCV) with newly approved therapies will likely place a tremendous economic burden on the country's health care system. The prediction comes from a cost-effectiveness analysis led by researchers at The University of Texas MD Anderson Cancer Center.

17 Mar 2015

Factors predictive of sequential nucleos(t)ide analogue, IFN-α therapy response identified

Hepatitis B surface antigen and hepatitis B core-related antigen levels can predict long-term response to sequential nucleos(t)ide analogue and interferon-α therapy in patients with chronic hepatitis B virus infection, research indicates.

13 Mar 2015

HBV genotype C HBeAg seroconversion rate ‘negligible’

Patients with chronic hepatitis B virus genotype C infection who are positive for hepatitis B e antigen should not delay antiviral treatment in the hope of seroconversion, Korean researchers recommend.

13 Mar 2015

Regenstrief researchers create accurate system for tracking quality of colonoscopies

An accurate system for tracking the quality of colonoscopies and determining the appropriate intervals between these procedures could contribute to both better health outcomes and lower costs. Clinician-researchers from the Regenstrief Institute have created and tested such a system in the nation's first multiple institution colonoscopy quality measurement study utilizing natural language processing and report that it is as accurate but less expensive than human review.

11 Mar 2015

MedUni Vienna experts recommend regular colonoscopy screening to prevent bowel cancer

Bowel cancer is one of the most common types of cancer. The prognosis depends greatly on the stage at which the tumour is discovered. Colonoscopy is regarded as the best method for identifying pre-cancerous changes. If these changes are treated promptly, the disease can be stopped in its tracks.

10 Mar 2015

Better understanding of stomach's response to infection could lead to therapies against gastric damage

A better understanding of the stomach's immune response to Helicobater pylori (H. pylori) infection could lead to new therapies targeting damage in the stomach, report researchers in the March issue of Cellular and Molecular Gastroenterology and Hepatology, the basic science journal of the American Gastroenterological Association.

6 Mar 2015

Biomarker for compilation of Risk Score for non-alcoholic steatohepatitis

40 percent of people in the EU suffer from non-alcoholic steatohepatitis (fatty liver disease), a disease which is becoming increasingly more frequent as a result of diabetes and excess weight in an affluent society. Currently, it is not possible to forecast the further course of the disease - right up to cirrhosis and cancer of the liver. Furthermore, an increased risk of heart attack and kidney damage exists. In future, this should become possible using a Risk Score with different biomarkers.

6 Mar 2015

SARAH study completes patient enrolment to evaluate treatment for primary liver cancer

SARAH, a large French study of patients with advanced, inoperable primary liver cancer (hepatocellular carcinoma, or HCC) has completed patient enrolment, exceeding its 400-patient target, according to its principal investigator, Professor Valérie Vilgrain MD, PhD, Department of Radiology, Beaujon Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP) and Université Paris Diderot, Sorbonne Paris Cité, France.

4 Mar 2015

Hepatology News and Research

Further Reading

Study: Alginate-enriched bread can reduce fat digestion, circulatory lipids in NAFLD patients

May issues of AGA's journals highlight important research updates on liver disease

New educational resource to help improve knowledge, treatment of Inflammatory Bowel Disease

Study calls for effective strategies to contain potential HDV epidemic in high-risk populations

Study reveals new target for research into liver disease

No effect of baseline cirrhosis on long-term TDF treatment outcomes

Study: Standard nursing assessments may help improve outcomes in cirrhosis patients

New simeprevir clinical data to be presented at EASL's International Liver Congress 2015

Exercise benefits obese, overweight people with NAFLD

NASH patients more likely to have increased intestinal permeability, shows study

Women with IBD may be at increased risk for developing cervical cancer

FDA approves CHOLBAM (cholic acid) for treatment of bile acid synthesis disorders

New hepatitis C drugs to place economic burden on health care system, predicts MD Anderson study

Factors predictive of sequential nucleos(t)ide analogue, IFN-α therapy response identified

HBV genotype C HBeAg seroconversion rate ‘negligible’

Regenstrief researchers create accurate system for tracking quality of colonoscopies

MedUni Vienna experts recommend regular colonoscopy screening to prevent bowel cancer

Better understanding of stomach's response to infection could lead to therapies against gastric damage

Biomarker for compilation of Risk Score for non-alcoholic steatohepatitis

SARAH study completes patient enrolment to evaluate treatment for primary liver cancer

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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