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Researchers shed light on the dual action of aspirin

Hugely popular non-steroidal anti-inflammation drugs like aspirin, naproxen (marketed as Aleve) and ibuprofen (Advil, Motrin) all work by inhibiting or killing an enzyme called cyclooxygenase - a key catalyst in production of hormone-like lipid compounds called prostaglandins that are linked to a variety of ailments, from headaches and arthritis to menstrual cramps and wound sepsis.

19 Aug 2014

iCo reports study results of Oral Amp B drug candidate targeting latent HIV reservoirs

iCo Therapeutics Inc., today reported results of its Oral Amphotericin B (Oral Amp B) drug candidate targeting latent HIV reservoirs.

19 Aug 2014

Natural killer cells can be used to combat acute lymphoblastic leukemia

Researchers at Children's Hospital Los Angeles have shown that a select team of immune-system cells from patients with leukemia can be multiplied in the lab, creating an army of natural killer cells that can be used to destroy the cancer cells.

19 Aug 2014

NTU research could lead to better treatment options for children suffering from leukaemia

A research team led by Nanyang Technological University scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

15 Aug 2014

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers at Karolinska Institutet in Sweden have found a method to repair the gene mutation causing agammaglobulinemia, an autoimmune deficiency disease that almost exclusively affects boys and in which the body lacks the ability to produce immunoglobulins (gamma globulin).

14 Aug 2014

Findings open up improved treatment possibilities for children suffering from leukaemia

A research team led by Nanyang Technological University (NTU) scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

14 Aug 2014

Epigenetics has a large say in blood formation

Blood stem cells have the potential to turn into any type of blood cell, whether it be the oxygen-carrying red blood cells, or the many types of white blood cells of the immune system that help fight infection.

12 Aug 2014

Study: Younger, older people likelier to visit ER repeatedly with gallstone pain before surgery

Gallstone pain is one of the most common reasons patients visit emergency rooms. Figuring out who needs emergency gallbladder removal and who can go home and schedule surgery at their convenience is sometimes a tricky question, and it isn't always answered correctly.

12 Aug 2014

Modulation of B cells may effectively treat symptoms of type 2 diabetes and periodontitis

Going to the dentist isn't fun for anyone, but for those with periodontal disease related to type 2 diabetes, a new research discovery may have them smiling.

1 Aug 2014

FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

The U.S. Food and Drug Administration today expanded the approved use of Imbruvica (ibrutinib) to treat patients with chronic lymphocytic leukemia (CLL) who carry a deletion in chromosome 17 (17p deletion), which is associated with poor responses to standard treatment for CLL. Imbruvica received a breakthrough therapy designation for this use.

29 Jul 2014

EMA CHMP adopts positive opinion for Janssen’s IMBRUVICA to treat CLL and MCL

Janssen-Cilag International NV announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorisation for IMBRUVICA (ibrutinib) in the European Union.

29 Jul 2014

University of Bradford researchers devise simple blood test to diagnose cancer

Researchers from the University of Bradford, UK, have devised a simple blood test that can be used to diagnose whether people have cancer or not.

29 Jul 2014

Zydelig gets FDA approval for treatment of patients with three types of blood cancers

The U.S. Food and Drug Administration today approved Zydelig (idelalisib) to treat patients with three types of blood cancers.

24 Jul 2014

Autoimmune diseases share certain pathogenic mechanisms with cancer

Autoimmune disorders may share certain pathogenic mechanisms with cancer, according to a new report by George Washington University researcher Linda Kusner, Ph.D., published in PLOS ONE on July 22.

23 Jul 2014

Study: Dietary elimination is successful method of treatment for adults with EoE

Dietary elimination is a successful method of treatment for adults with eosinophilic esophagitis (EoE), according to a new study1 in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

21 Jul 2014

Scientists identify genes that may help predict steroid responsiveness in people with EoE

Results from a clinical trial show that high doses of the corticosteroid fluticasone propionate safely and effectively induce remission in many people with eosinophilic esophagitis (EoE), a chronic inflammatory disease of the esophagus characterized by high levels of white blood cells called eosinophils.

19 Jul 2014

Researchers release evidence substantiating unexpected dual role of immune system

University of Leicester researchers have released evidence substantiating an unexpected dual role of an important component of the immune system.

17 Jul 2014

Women with history of pregnancy loss are at higher risk for cardiovascular disease later

The Annals of Family Medicine today published an article detailing research showing that women with a history of pregnancy loss are at higher risk for cardiovascular disease later in adulthood than other women, work completed by physicians in the Center for Primary Care and Prevention (CPCP) at Memorial Hospital of Rhode Island.

17 Jul 2014

Scientists build artificial cells programmed to eat their undesirable neighbors

A team of researchers has devised a Pac-Man-style power pellet that gets normally mild-mannered cells to gobble up their undesirable neighbors. The development may point the way to therapies that enlist patients’ own cells to better fend off infection and even cancer, the researchers say. A description of the work will be published July 15 in the journal Science Signaling.

16 Jul 2014

New tools for detecting and monitoring TB in captive elephants

Mycobacterium tuberculosis, the organism that causes tuberculosis in humans, also afflicts Asian (and occasionally other) elephants. Diagnosing and treating elephants with TB is a challenge, however, as little is known about how their immune systems respond to the infection.

16 Jul 2014

Leukocyte News and Research

Researchers shed light on the dual action of aspirin

iCo reports study results of Oral Amp B drug candidate targeting latent HIV reservoirs

Natural killer cells can be used to combat acute lymphoblastic leukemia

NTU research could lead to better treatment options for children suffering from leukaemia

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Findings open up improved treatment possibilities for children suffering from leukaemia

Epigenetics has a large say in blood formation

Study: Younger, older people likelier to visit ER repeatedly with gallstone pain before surgery

Modulation of B cells may effectively treat symptoms of type 2 diabetes and periodontitis

FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

EMA CHMP adopts positive opinion for Janssen’s IMBRUVICA to treat CLL and MCL

University of Bradford researchers devise simple blood test to diagnose cancer

Zydelig gets FDA approval for treatment of patients with three types of blood cancers

Autoimmune diseases share certain pathogenic mechanisms with cancer

Study: Dietary elimination is successful method of treatment for adults with EoE

Scientists identify genes that may help predict steroid responsiveness in people with EoE

Researchers release evidence substantiating unexpected dual role of immune system

Women with history of pregnancy loss are at higher risk for cardiovascular disease later

Scientists build artificial cells programmed to eat their undesirable neighbors

New tools for detecting and monitoring TB in captive elephants

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