Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Study links congenital kidney disease with neurodevelopmental disorders

About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study by Columbia University Medical Center (CUMC) researchers has shown.

16 Nov 2012

Peak interest in health issues comes at about age 51 for baby boomers

For baby boomers, the peak interest in health issues comes at about age 51, with a second peak coming near age 65, according to a new study.

16 Nov 2012

Tolvaptan improves kidney health in polycystic kidney disease

A vasopressin V2-receptor blocker slows the increase in total kidney volume and decline in kidney function in patients with autosomal dominant polycystic kidney disease, report US researchers.

12 Nov 2012

CHOP presents new findings on pediatric cardiovascular disease at AHA 2012

Physician-researchers from the Cardiac Center at The Children's Hospital of Philadelphia presented new findings on pediatric cardiovascular disease at the American Heart Association's Scientific Sessions 2012 in Los Angeles.

9 Nov 2012

New communication training could help nephrology fellows to discuss serious news with patients

Kidney specialists, or nephrologists, care for a medically complex population and frequently must discuss serious news with patients: giving a diagnosis of kidney disease, explaining the risks and benefits of treatments, and defining care goals at the end of life. Yet nephrologists do not routinely receive formal education on how to engage in these types of conversations.

9 Nov 2012

Excessive turnover of placental cells may trigger unnatural increase in blood pressure

Excessive turnover of cells in the placenta may trigger an unnatural increase in blood pressure that puts mother and baby at risk, researchers say.

7 Nov 2012

Detailing Medicare's 2013 doc pay schedules: Home health flat, primary care up

Under Medicare's 2013 payment schedule, released late last week, home health agency payments will remain flat while primary care physicians can expect up to a 7 percent boost in payments.

6 Nov 2012

Tengion receives U.S. patent allowance titled ‘Isolated Renal Cells and Uses Thereof’

Tengion, Inc., a leader in regenerative medicine, today announced that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance for U.S. Patent Application No. 12/617,721, titled "Isolated Renal Cells and Uses Thereof."

5 Nov 2012

Study highlights potential treatment that reduces kidney growth

Autosomal-dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders, affecting one in every 1,000 people and responsible for up to ten percent of patients on dialysis worldwide. The disease is characterized by the development of cysts that lead to progressive kidney failure and necessitate dialysis or a kidney transplant in most patients aged around fifty. Moreover, the persistent cyst growth causes high blood pressure and painful complications.

5 Nov 2012

New information related to kidney transplantation

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information related to kidney transplantation—specifically, the post-transplant health of kidney donors and the racial disparities faced by children in need of transplants.

3 Nov 2012

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say.

3 Nov 2012

Genkyotex announces positive results from GKT137831 Phase I studies on healthy subjects

Genkyotex, the leading developer of NOX inhibitors to treat oxygen-radical mediated diseases, announced today that Phase I studies have demonstrated excellent safety and tolerability following single and multiple oral doses of GKT137831, the first in class NOX 1 and 4 inhibitor. In addition, GKT137831 demonstrated a favourable pharmacokinetic profile in these subjects.

3 Nov 2012

Studies provide new information on diet and blood pressure in kidney disease patients

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information on diet and blood pressure in kidney disease patients.

3 Nov 2012

State of glycocalyx barrier indicates vascular risk in dialysis patients

The glycocalyx barrier – a mesh of proteoglycans and associated glycosaminoglycans present on vascular endothelium – is impaired in patients with renal failure, probably contributing to their predisposition to endothelial dysfunction and vascular disease, say researchers.

2 Nov 2012

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

Affymax, Inc. and Takeda Pharmaceuticals U.S.A., Inc. (TPUSA) today announced the presentation of post-hoc sub-group analyses of the EMERALD Phase 3 studies that evaluated OMONTYS (peginesatide) Injection, an erythropoiesis-stimulating agent (ESA), for the treatment of anemia due to chronic kidney disease (CKD) in adult dialysis patients.

2 Nov 2012

FibroGen announces presentation of FG-4592 Phase 2 data on anemia at ASN Kidney Week 2012

FibroGen, Inc., today announced that two abstracts relating to FG-4592, its oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) clinical candidate for the treatment of anemia in chronic kidney disease, have been accepted for oral and poster presentations at the American Society of Nephrology (ASN) Kidney Week 2012.

1 Nov 2012

Chronic kidney disease associated with increased risk of death regardless of age

A new study from the Johns Hopkins Bloomberg School of Public Health and the Chronic Kidney Disease Prognosis Consortium found that chronic kidney disease and its complications were associated with a higher risk of death regardless of age.

1 Nov 2012

Adolescent overweight and obesity may increase risk of all-cause ESRD

Being overweight and obese during adolescence appears related to an increased risk of all-cause treated end-stage renal disease (ESRD) during a 25-year period, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.

30 Oct 2012

LVEDP-guided hydration effectively prevents CI-AKI in patients undergoing cardiac catheterization

A hydration regimen tailored to the patient's fluid status was effective in reducing damage to kidneys in patients undergoing cardiac catheterization, according to a study presented at the 24th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation. TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

26 Oct 2012

Guidelines to help protect vulnerable populations from flu

While it is important to get vaccinated against the flu virus as early as possible, it is never too late to reap the benefits of this vaccine. According to The Centers for Disease Control and Prevention, the peak months for the spread of the flu virus are January and February and the season can last into mid-May.

26 Oct 2012

Nephropathy News and Research

Further Reading

Study links congenital kidney disease with neurodevelopmental disorders

Peak interest in health issues comes at about age 51 for baby boomers

Tolvaptan improves kidney health in polycystic kidney disease

CHOP presents new findings on pediatric cardiovascular disease at AHA 2012

New communication training could help nephrology fellows to discuss serious news with patients

Excessive turnover of placental cells may trigger unnatural increase in blood pressure

Detailing Medicare's 2013 doc pay schedules: Home health flat, primary care up

Tengion receives U.S. patent allowance titled ‘Isolated Renal Cells and Uses Thereof’

Study highlights potential treatment that reduces kidney growth

New information related to kidney transplantation

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

Genkyotex announces positive results from GKT137831 Phase I studies on healthy subjects

Studies provide new information on diet and blood pressure in kidney disease patients

State of glycocalyx barrier indicates vascular risk in dialysis patients

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

FibroGen announces presentation of FG-4592 Phase 2 data on anemia at ASN Kidney Week 2012

Chronic kidney disease associated with increased risk of death regardless of age

Adolescent overweight and obesity may increase risk of all-cause ESRD

LVEDP-guided hydration effectively prevents CI-AKI in patients undergoing cardiac catheterization

Guidelines to help protect vulnerable populations from flu

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